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  1. 11001
    por Bennett, C. Verity, Goswami, Anjali
    Publicado 2012
    “…Landmark data was treated with Procrustes superimposition to remove all nonshape differences and then subjected to principal components analysis and linear discriminant function analysis. Haplorhines and strepsirrhines were well separated in morphospace along the major components of variation, largely reflecting differences in relative skull length and width and facial depth. …”
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    Morphometric Analysis of Cranial Shape in Fossil and Recent Euprimates
  2. 11002
    “…Using two approaches, trajectory matching and discriminant function analysis, we find that even in our best-case scenario (with accurate knowledge of epidemiological parameters, and precise times of death), it was not possible to reliably predict the outcome of a stochastic Susceptible-Exposed–Infectious-Recovered (SEIR) process.…”
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    Estimating the Probability of a Major Outbreak from the Timing of Early Cases: An Indeterminate Problem?
  3. 11003
    “…Stochastic frontier production function analysis was used to estimate the technical efficiency in milk production. …”
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    Technical efficiency in milk production in underdeveloped production environment of India*
  4. 11004
    por Thayer, Zaneta M., Dobson, Seth D.
    Publicado 2013
    “…Elliptical Fourier functions analysis was used to quantify chin shape, and principle components analysis was used to compute shape descriptors. …”
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    Geographic Variation in Chin Shape Challenges the Universal Facial Attractiveness Hypothesis
  5. 11005
    “…Protein structure alignment is a crucial step in protein structure–function analysis. Despite the advances in protein structure alignment algorithms, some of the local conformationally similar regions are mislabeled as structurally variable regions (SVRs). …”
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    DoSA: Database of Structural Alignments
  6. 11006
    “…Here, we use mouse genetics and structure function analysis to investigate SLX1 function. Disrupting the murine Slx1 and Slx4 genes revealed that they are essential for HJ resolution in mitotic cells. …”
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    Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases
  7. 11007
    “…At the level of the nuclear pore complex (NPC), Nup358, a nucleoporin that forms the cytoplasmic filaments of the NPC, plays an important role in nuclear import of hTERT. A structure-function analysis of Nup358 revealed that the zinc finger region of the nucleoporin is of particular importance for transport of hTERT. …”
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    Importin 7 and Nup358 Promote Nuclear Import of the Protein Component of Human Telomerase
  8. 11008
    “…The percentage of sexual dimorphism for each parameter was calculated. Discriminant function analysis was used to determine the accuracy of sex determination for each molar separately and both the molars taken together. …”
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    Sex determination potential of permanent maxillary molar widths and cusp diameters in a North Indian population
  9. 11009
    “…Although FRQ-dependent repression of WCC has been extensively studied, the mechanism by which the WCC initiates a circadian cycle remains elusive. Structure/function analysis of WC-1 eliminated domains previously thought to transactivate frq expression but instead identified amino acids 100–200 as essential for frq circadian expression. …”
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    Neurospora WC-1 Recruits SWI/SNF to Remodel frequency and Initiate a Circadian Cycle
  10. 11010
    “…This advance enables easy assessment of the off target effects associated with gene disruption, as well as phenotype-based structure-function analysis. In our study, we used the Fan1 DNA repair gene as control in these experiments. …”
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    Improved Genome Editing in Human Cell Lines Using the CRISPR Method
  11. 11011
    por Wu, Ke, Hoy, Marjorie A.
    Publicado 2014
    “…In the current study, we performed a loss-of-function analysis of the clathrin heavy chain gene in M. occidentalis using RNAi. …”
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    Clathrin Heavy Chain Is Important for Viability, Oviposition, Embryogenesis and, Possibly, Systemic RNAi Response in the Predatory Mite Metaseiulus occidentalis
  12. 11012
    “…Stress-rest with gated and non-gated image sets were accumulated for myocardial perfusion imaging and could be used for perfusion defect scoring and normal left ventricular (LV) function analysis. For single-photon emission computed tomography (SPECT) with multi-focal collimator design, databases of supine and prone positions and computed tomography (CT)-based attenuation correction were created. …”
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    Normal values and standardization of parameters in nuclear cardiology: Japanese Society of Nuclear Medicine working group database
  13. 11013
    “…Using a combination of molecular modeling and structure–function analysis we confirm and extend these findings providing evidence for high conservation of the L endonuclease between Old and New World hantaviruses. …”
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    Conserved Endonuclease Function of Hantavirus L Polymerase
  14. 11014
    “…Although structures of GSAM from archaea and bacteria have been resolved, a GSAM structure from a higher plant is not available, preventing further structure–function analysis. Here, the structure of GSAM from Arabidopsis thaliana (AtGSA1) obtained by X-ray crystallography is reported at 1.25 Å resolution. …”
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    Crystal structure of glutamate-1-semialdehyde-2,1-aminomutase from Arabidopsis thaliana
  15. 11015
    “…At 13 wpi, 2452 genes were downregulated while only 604 genes were upregulated in HLB infected ponkan leaves but no pathway enrichment was identified. Gene function analysis showed impairment in defense at the early stage of infection. …”
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    Digital Gene Expression Analysis of Ponkan Mandarin (Citrus reticulata Blanco) in Response to Asia Citrus Psyllid-Vectored Huanglongbing Infection
  16. 11016
    “…These findings provide a theoretical framework for understanding the differential actions of TRP channel ligands, with important ramifications for TRP channel structure-function analysis and pharmacology. DOI: http://dx.doi.org/10.7554/eLife.17240.001…”
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    Definition of two agonist types at the mammalian cold-activated channel TRPM8
  17. 11017
    “…The system described here enables easy structure-function analysis of LRRC8 proteins.…”
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    Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes
  18. 11018
    “…Using transgenic Plasmodium berghei parasites, we show in this structure-function analysis that mutagenesis of the amino- or carboxy-terminal cysteine motif causes marked reductions in IMC1a protein levels in the parasite, which are accompanied by partial losses of sporozoite shape and infectivity. …”
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    The Plasmodium alveolin IMC1a is stabilised by its terminal cysteine motifs and facilitates sporozoite morphogenesis and infectivity in a dose-dependent manner
  19. 11019
    “…MANOVA and follow-up discriminant function analysis revealed somatotype differences among playing positions with centers and opposites being endomorph-ectomorph and hitters being central. …”
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    Somatotype, Level of Competition, and Performance in Attack in Elite Male Volleyball
  20. 11020
    “…BioID analysis showed that AIRE associates with spindle-associated proteins in mES cells. Loss of function analysis revealed that Aire was important for centrosome number regulation and spindle pole integrity specifically in mES cells. …”
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    AIRE is a critical spindle-associated protein in embryonic stem cells
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