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Análisis funcional
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Climatic variables influence annual P. montezumae growth
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11141“…The present study found 84.8% accuracy after subjecting the obtained value to discriminant function analysis. CONCLUSION: The morphometric analysis of the orbital aperture using postero-anterior cephalogram can be used as an adjuvant for personal and gender identification in forensic anthropology.…”
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11142“…A Xenopus oocyte expression system and two-electrode voltage-clamp recording further verified the function analysis of TchiGR43a. Electrophysiological results showed that TchiGR43a was exclusively tuned to D-fructose. …”
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11143por Tu, Jian, Peng, Qiliang, Shen, Yi, Hong, Yin, Zhu, Jiahao, Feng, Zhengyang, Zhou, Ping, Fan, Shaonan, Zhu, Yaqun, Zhang, Yongsheng“…Targets of miRNAs were predicted and enriched by biological function analysis. Key target mRNAs of the biomarker miRNAs were screened from protein-protein interaction network and gene expression profiles, respectively. …”
Publicado 2019
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11144“…A diagnostic survey with an author’s questionnaire was used in the study, which helped to survey 1128 respondents from Eastern Poland—that is, from the Podlaskie, Lublin, and Subcarpathia regions—and 1072 from Western Ukraine, including the Volyn, Lviv, and Transcarpathia regions. Discriminant function analysis was used in statistical analysis. Both residents of Eastern Poland and Western Ukraine obtained information on regional food products from their friends or family and from television (TV), internet, and regional fairs. …”
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11145“…Until now, there have been no 3D structural studies of these enzymes, thereby preventing structure–function analysis. To enable such investigations, the present work describes the model-based structural and functional characterization of a phosphodiesterase from Crotalus adamanteus venom, named PDE_Ca. (2) Methods. …”
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11146“…Here we generated mutations in zebrafish rps9, a rarely studied ribosomal protein gene, and investigated its function. Analysis of this mutant demonstrates that rps9 disruption leads to impairment of erythrocyte maturation, resulting in anemia. …”
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11147“…To observe the association of alcohol induced CCA pathogenesis, we combined differentially expressed genes (DEGs) with computational bioinformatics of CCA by using publicly gene expression omnibus (GEO) datasets. For biological function analysis, Gene ontology (GO) analysis showed biological process and molecular function related to regulation of transcription from RNA polymerase II promoter, while cellular component linked to the nucleoplasm. …”
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11148por Reichhardt, Martin P., Johnson, Steven, Tang, Terence, Morgan, Thomas, Tebeka, Nchimunya, Popitsch, Niko, Deme, Justin C., Jore, Matthijs M., Lea, Susan M.“…We thus present the fold of the CirpT protein family, and provide detailed mechanistic insights into its inhibitory function. Analysis of the binding interface reveals a mechanism of C5 inhibition, and provides information to expand our biological understanding of the activation of C5, and thus the terminal complement pathway.…”
Publicado 2020
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11149por Hasiniaina, Alida Frankline, Radespiel, Ute, Kessler, Sharon E., Rina Evasoa, Mamy, Rasoloharijaona, Solofonirina, Randrianambinina, Blanchard, Zimmermann, Elke, Schmidt, Sabine, Scheumann, Marina“…Genetically defined species were discriminated reliably on the phenotypic level based on their acoustic distinctiveness in a discriminant function analysis. Acoustic variation was explained by genetic distance, whereas differences in morphology, forest type, or geographic distance had no effect. …”
Publicado 2020
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11150“…A subsequent discriminant function analysis correctly classified 98.2% of participants. …”
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11151por Qu, Shenghua, Wang, Xiaoyan, Yang, Lixin, Lv, Junfeng, Meng, Runze, Dai, Weiqian, Li, Qingxiangzi, Liu, Huicong, Zhang, Bing, Zhang, Dabing“…Western blot analyses of a series of truncated rEDIII proteins showed that the epitope recognized by 12F11 includes amino acids between residues 8 and 77 of EDIII protein. Function analysis demonstrated that 12F11 neutralizes TMUV infection at virus adsorption and at a step after adsorption to a certain extent. …”
Publicado 2020
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11152“…Moreover, the genes involved in nicotinamide adenine dinucleotide metabolism were negatively correlated with the expression of BRAF in the high-risk group. Function analysis revealed that the upregulated genes in the high-risk group were enriched in the cytochrome P450-mediated metabolism of chemical carcinogens. …”
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11153por Bis, Gabriela, Szlasa, Wojciech, Sondaj, Katarzyna, Zendran, Iga, Mielcarek-Siedziuk, Monika, Barg, Ewa“…Patients require long term follow up including lipid metabolism and thyroid function analysis. HSCT survivors demand introduction of polyunsaturated fatty acids into the diet to reduce risk of developing the lipid complications.…”
Publicado 2020
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11154“…Due to their possible functional redundancy, gain-of-function analysis is helpful to reveal their respective biological functions. …”
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11155por Zhang, Shichao, Hu, Zuquan, Lan, Yingwu, Long, Jinhua, Wang, Yun, Chen, Xiaowen, Xu, Xiaofeng, Zeng, Zhu, Ouyang, Yan“…Furthermore, the correlation and function analysis identified CELF2, BAG2, RBFOX2, PTBP2 and QKI as hub splicing factors, and the focal adhesion signaling pathway was most significantly correlated with survival-associated alternative splicing events. …”
Publicado 2020
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11156“…Gain- and loss-of-function analysis demonstrated that MTHFD2 knockdown or miR-92a overexpression notably inhibited proliferation and promoted apoptosis of AML cell lines. …”
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11157por He, Saifei, Zhang, Miao, Ye, Ying, Song, Yanan, Ma, Xing, Wang, Guoyu, Zhuang, Juhua, Xia, Wei, Zhao, Bin“…In the present study, biological function analysis demonstrated that GINS2 interference attenuated cell viability, migration and invasion in TC cell lines (K1 and SW579). …”
Publicado 2021
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11158“…Full-length transcriptome sequencing is an efficient method for molecular study of P. striolata and it is also useful for gene function analysis.…”
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11159por van den Kerkhof, Danique L., van der Meijden, Paola E.J., Hackeng, Tilman M., Dijkgraaf, Ingrid“…No new αIIbβ3 inhibitors are developed since the approval of current platelet antagonists, and structure-function analysis of exogenous disintegrins could help find platelet antagonists with fewer adverse side effects.…”
Publicado 2021
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11160“…The HOMO-LUMO, MEP, and Fukui function analysis has been used to elucidate the information regarding charge transfer within the molecule. …”
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