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11341Structural analysis and ionic conduction mechanism of sulfide-based solid electrolytes doped with Brpor Yamaguchi, Hiroshi, Kobayashi, Kentaro, Hiroi, Satoshi, Utsuno, Futoshi, Ohara, Koji“…This analysis relies on the pair distribution function analysis obtained from high-energy X-ray diffraction. …”
Publicado 2023
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11342por Liu, Shihai, Mao, Qinwen, Zhang, Weifeng, Zheng, Xiaojing, Bian, Ye, Wang, Dongyang, Li, Huijin, Chai, Lihong, Zhao, Junli, Xia, Haibin“…This new vector would be valuable in gene-function analysis and for gene therapy in cancer.…”
Publicado 2009
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11343por Bagheri, Hedayat, El-Soda, Mohamed, van Oorschot, Inge, Hanhart, Corrie, Bonnema, Guusje, Jansen-van den Bosch, Tanja, Mank, Rolf, Keurentjes, Joost J. B., Meng, Lin, Wu, Jian, Koornneef, Maarten, Aarts, Mark G. M.“…The genetic analysis shows that this population is a useful new tool for analyzing genetic variation for interesting traits in B. rapa, and for further exploitation of the recent availability of the B. rapa whole genome sequence for gene cloning and gene function analysis.…”
Publicado 2012
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11344por Kim, Yong-Il, No Lee, Joon, Bhandari, Sushil, Nam, In-Koo, Yoo, Kyeong-Won, Kim, Se-Jin, Oh, Gi-Su, Kim, Hyung-Jin, So, Hong-Seob, Choe, Seong-Kyu, Park, Raekil“…Gene expression analysis indicates that esrra is expressed in developing pharyngeal arches where genes necessary for cartilage development are also expressed. Loss of function analysis shows that knockdown of esrra impairs expression of genes including sox9, col2a1, sox5, sox6, runx2 and col10a1 thus induces abnormally formed cartilage in pharyngeal arches. …”
Publicado 2015
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11345por Imae, Rieko, Dejima, Katsufumi, Kage-Nakadai, Eriko, Arai, Hiroyuki, Mitani, Shohei“…Tissue-specific rescue experiments indicate that RSD-3 is required for importing silencing RNA into cells rather than exporting from cells. Structure/function analysis showed that the ENTH domain alone is sufficient, and membrane association of the ENTH domain is required, for RSD-3 function in systemic RNAi. …”
Publicado 2016
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11346por Zhang, Kezhong, Wang, Guohui, Zhang, Xuebao, Hüttemann, Philipp P., Qiu, Yining, Liu, Jenney, Mitchell, Allison, Lee, Icksoo, Zhang, Chao, Lee, Jin-sook, Pecina, Petr, Wu, Guojun, Yang, Zeng-quan, Hüttemann, Maik, Grossman, Lawrence I.“…Gain- and loss-of-function analysis demonstrates that COX7AR is required for human breast cancer cells to maintain higher rates of proliferation, clone formation, and invasion. …”
Publicado 2016
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11347por Larina, Irina M., Percy, Andrew J., Yang, Juncong, Borchers, Christoph H., Nosovsky, Andrei M., Grigoriev, Anatoli I., Nikolaev, Evgeny N.“…Linear discriminant function analysis of the quantitative results revealed three distinct groups of proteins: 1) proteins with post-flight protein concentrations remaining stable, 2) proteins whose concentrations recovered slowly, or 3) proteins whose concentrations recovered rapidly to their pre-flight levels. …”
Publicado 2017
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11348por Zhu, Bo, He, Quanze, Xiang, Jingjing, Qi, Fang, Cai, Hao, Mao, Jun, Zhang, Chunhua, Zhang, Qin, Li, Haibo, Lu, Lu, Wang, Ting, Yu, Wenbo“…We found that the number of identified phosphoproteins and phosphosites in these cells were negatively correlated with their proliferative abilities. The function analysis suggested that the aberrant phosphorylation of SR proteins and activation of MAPK pathway might be two critical factors to promote cancer cell proliferation. …”
Publicado 2017
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11349por Xu, Xiaoliang, Yin, Yin, Tang, Junwei, Xie, Yu, Han, Zhuo, Zhang, Xudong, Liu, Qiaoyu, Qin, Xihu, Huang, Xinli, Sun, Beicheng“…The gain- and loss-of-function analysis revealed that Lnc-Myd88 could promote the proliferation and metastasis of HCC both in vitro and in vivo. …”
Publicado 2017
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11350por Jenkins, Samir V., Vang, Kieng B., Gies, Allen, Griffin, Robert J., Jun, Se-Ran, Nookaew, Intawat, Dings, Ruud P. M.“…Distinct changes were also seen in the phyla and bacterial species abundance per storage strategy. Metabolic function analysis showed 22 pathways not significantly affected by storage conditions, whereas the tyrosine metabolism pathway was significantly changed in all strategies except by EDTA. …”
Publicado 2018
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11351“…RESULTS: HOTAIR expression in CSCC cell lines exhibited an obvious elevation. Cell function analysis revealed that HOTAIR overexpression remarkably facilitated CSCC cell migration, proliferation and EMT process, which were impeded by down-regulation of HOTAIR. …”
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11352por Lortie, Christopher J., Braun, Jenna, Westphal, Michael, Noble, Taylor, Zuliani, Mario, Nix, Emmeleia, Ghazian, Nargol, Owen, Malory, Scott Butterfield, H.“…Using Gambelia sila, one of the first vertebrate species listed as endangered, we used resource selection function analysis of telemetry and remotely sensed data to identity key drivers of selected versus available locations for this species in Carrizo Plain National Monument, USA. …”
Publicado 2020
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11353por Huang, Gai, Wu, Zhiguo, Percy, Richard G., Bai, Mingzhou, Li, Yang, Frelichowski, James E., Hu, Jiang, Wang, Kun, Yu, John Z., Zhu, Yuxian“…Gaussian probability density function analysis indicates that several long-terminal-repeat bursts that occurred from 5.7 million years ago to less than 0.61 million years ago contributed compellingly to A-genome size expansion, speciation and evolution. …”
Publicado 2020
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11354“…These advances dramatically increase the feasibility of detailed structure–function analysis of the clusterin molecule and will facilitate identification of those specific regions responsible for the interactions of clusterin with receptors and other molecules.…”
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11355“…Based on current evidence and structure-function analysis, multiple bioactive peptides present potency to neutralize the virus. …”
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11356por Zhou, Daming, Dejnirattisai, Wanwisa, Supasa, Piyada, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Tuekprakhon, Aekkachai, Nutalai, Rungtiwa, Wang, Beibei, Paesen, Guido C., Lopez-Camacho, Cesar, Slon-Campos, Jose, Hallis, Bassam, Coombes, Naomi, Bewley, Kevin, Charlton, Sue, Walter, Thomas S., Skelly, Donal, Lumley, Sheila F., Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah, James, William, Carroll, Miles W., Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.“…Here, we describe a structure-function analysis of B.1.351 using a large cohort of convalescent and vaccinee serum samples. …”
Publicado 2021
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11357por Quiroga-González, Camilo, Cardenas, Luis Alberto Chica, Ramírez, Mónica, Reyes, Alejandro, González, Camila, Stevenson, Pablo R.“…Beta diversity and functionality analysis showed separation of samples from released and captive conditions and the major factor of variation was the moment of liberation. …”
Publicado 2021
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11358por Han, Xiaojian, Wang, Yingming, Li, Shenglong, Hu, Chao, Li, Tingting, Gu, Chenjian, Wang, Kai, Shen, Meiying, Wang, Jianwei, Hu, Jie, Wu, Ruixin, Mu, Song, Gong, Fang, Chen, Qian, Gao, Fengxia, Huang, Jingjing, Long, Yingyi, Luo, Feiyang, Song, Shuyi, Long, Shunhua, Hao, Yanan, Li, Luo, Wu, Yang, Xu, Wei, Cai, Xia, Gao, Qingzhu, Zhang, Guiji, He, Changlong, Deng, Kun, Du, Li, Nai, Yaru, Wang, Wang, Xie, Youhua, Qu, Di, Huang, Ailong, Tang, Ni, Jin, Aishun“…Here, we integrated and optimized a strategically screening method for NAbs, which has enabled us to obtain SARS-CoV-2 receptor-binding domain (RBD) specific NAbs within 6 days, followed by additional 9 days for antibody production and function analysis. Using this method, we obtained 198 specific Abs against SARS-CoV-2 RBD from the blood samples of COVID-19 convalescent patients, and 96 of them showed neutralizing activity. …”
Publicado 2021
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11359por Vishweshwaraiah, Yashavantha L., Acharya, Abhishek, Hegde, Vinayak, Prakash, Balaji“…Insights obtained from classical structure-function analysis of natural peptides and their mutants through antimicrobial and enzymatic assays are used to rationally develop a set of peptides. pH and thermostability assays were performed to demonstrate robust antimicrobial activity post-treatment with high temperatures and at wide pH ranges. …”
Publicado 2021
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11360por Li, Shupeng, Li, Lulu, Meng, Xiangqi, Sun, Penggang, Liu, Yi, Song, Yuntang, Zhang, Sijia, Jiang, Chuanlu, Cai, Jinquan, Zhao, Zheng“…The DREAM database also provides some data visualization and online analysis services such as volcano plot, GO/KEGG enrichment function analysis, and novel drug discovery analysis. We hope the DREAM database should serve as a valuable resource for clinical practice and basic research, which could help researchers better understand the effects of protein-coding RNAs on drug response in human cancers.…”
Publicado 2021
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