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  1. 11881
    “…Alterations in HDFs provide the earliest signs of impaired cardiac physiology and can therefore transform the existing paradigm of cardiac function analysis once implemented in routine clinical care. …”
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    Introduction to Hemodynamic Forces Analysis: Moving Into the New Frontier of Cardiac Deformation Analysis
  2. 11882
    “…These observations through structure–function analysis suggested that only two OB folds rather than four OB folds in PaSSB are enough for the formation of a stable complex with ssDNA. …”
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    Characterization of an SSB–dT25 complex: structural insights into the S-shaped ssDNA binding conformation
  3. 11883
    “…Here, we performed a structure–function analysis of Sas20 and determined that it features two discrete starch-binding domains separated by a flexible linker. …”
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    Sas20 is a highly flexible starch-binding protein in the Ruminococcus bromii cell-surface amylosome
  4. 11884
    por Zhang, Qian, Li, Jian, Weng, Ling
    Publicado 2022
    “…Five ARDEGs (GFAP, PDGFRB, PLOD1, MAP4K4, and NFKBIA) were obtained. For biological function analysis, aging, cellular senescence, and Ras protein signal transduction regulation were enriched. …”
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    Identification and Validation of Aging-Related Genes in Alzheimer’s Disease
  5. 11885
    “…Here, we employed a loss-of-function analysis with human A549 respiratory epithelial cells with a knockout (KO) of the type I IFN receptor (IFNAR KO), either solely or together with the receptor of type III IFN (IFNAR/IFNLR1 KO). …”
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    Interferon Signaling-Dependent Contribution of Glycolysis to Rubella Virus Infection
  6. 11886
    “…Using a computational model of the AC6–Gαs complex, we predicted key nitrosylation‐amenable cysteine residues involved in the interaction of AC6 with Gαs and pursued a structure–function analysis of these cysteine residues in both AC6 and Gαs. …”
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    Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs
  7. 11887
    “…Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that DEGs were involved in TLR signaling, the RIG-I-Like receptor signaling pathway, the IL-17 signaling pathway, and the NFkB signaling pathway. Function analysis indicated that DEGs were associated with Toll-like receptor 2 binding, Lipopeptide binding, Toll-like receptor binding, and NAD(P)+ nucleosidase activity. …”
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    Regulation of Key Immune-Related Genes in the Heart Following Burn Injury
  8. 11888
    “…With the help of Perl language, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis and gene function analysis (GO) enrichment analysis were carried out by using the biological program package of R language. …”
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    To study the mechanism of Scutellariae Radix and Astragaloside in the treatment of lung cancer based on network pharmacology
  9. 11889
    “…TIG welding parameters were optimized in this study using a Taguchi-based desirability function analysis (DFA). From the experimental results, it was observed that welded samples employing ER-309L filler wires had a microstructure consisting of a delta ferrite network in an austenite matrix. …”
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    Experimental Investigation and Parametric Optimization of the Tungsten Inert Gas Welding Process Parameters of Dissimilar Metals
  10. 11890
    “…In this study, we constructed a weighted gene co-expression network and identified several key modules and networks overrepresented in LUAD, including the E2F2-centered transcription regulatory network. Function analysis revealed that E2F2 overexpression accelerated cell growth, cell cycle progression and cell motility in LUAD cells whereas E2F2 knockdown inhibited these malignant phenotypes. …”
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    E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry
  11. 11891
    “…The Cynanchum paniculatum-active compound-potential target network and protein-protein interaction network were constructed by using Cytoscape software, and then biological function analysis and KEGG pathway enrichment analysis were performed using the DAVID. …”
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    Network Pharmacological Study on the Mechanism of Cynanchum paniculatum (Xuchangqing) in the Treatment of Bungarus multicinctus Bites
  12. 11892
    por Ye, Hui
    Publicado 2022
    “…The location of axonal activation was dependent on both the parameters of the stimulus and the biophysics properties of the targeted axon during μMS. The activating function analysis predicted that the location of membrane depolarization and activation could shift due to the reversal of the coil current and the change in the coil-axon distance. …”
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    Finding the Location of Axonal Activation by a Miniature Magnetic Coil
  13. 11893
    “…Differential item functioning analysis (DIF) and confirmatory factor analysis were conducted. …”
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    Investigating method effects associated with the wording direction of items of the Social Physique Anxiety Scale
  14. 11894
    “…In this study, we used empirical orthogonal function analysis to identify the main components of variability in a global data set of 422 annual time series of Chlorophyll a fluorescence and optical backscatter profiles. …”
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    Biogeographical Classification of the Global Ocean From BGC‐Argo Floats
  15. 11895
    “…ST8SIA1 expression levels were negatively correlated with tumor purity and positively associated with infiltrated immune cells and expression of immune checkpoint genes. Function analysis also revealed that ST8SIA1 was significantly associated with immune-related pathways. …”
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    Identifying an Immune-Related Gene ST8SIA1 as a Novel Target in Patients With Clear-Cell Renal Cell Carcinoma
  16. 11896
    “…In addition, the scattering phase function analysis and Monte Carlo simulation based on the cylindrical scatterers reveal that the diattenuation parameter D images with different imaging resolutions are expected to be used to distinguish among the fibrous scatterers in the medium with different particle sizes. …”
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    Analyzing the Influence of Imaging Resolution on Polarization Properties of Scattering Media Obtained From Mueller Matrix
  17. 11897
    “…Nevertheless, CHMP4A and CHMP4C can enhance the activity of CHMP4B, raising the possibility that they can form heteropolymers in vivo. Our structure-function analysis of the LGD1 and LGD2 indicates that the C2 domain of the LGD proteins has a specific function beyond protein stability and subcellular localisation. …”
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    Using Drosophila melanogaster to Analyse the Human Paralogs of the ESCRT-III Core Component Shrub/CHMP4/Snf7 and Its Interactions with Members of the LGD/CC2D1 Family
  18. 11898
    por Peng, Feng, Xiao, Fengchun, Lin, Long
    Publicado 2022
    “…Mouse airway lung dynamic compliance (Cdyn) and total airway resistance (RL) were measured by the EMKA animal lung function analysis system. The inflammation factor levels were estimated by ELISA. …”
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    Protective Effects of Platycodin D3 on Airway Remodeling and Inflammation via Modulating MAPK/NF-κB Signaling Pathway in Asthma Mice
  19. 11899
    “…It becomes more conservative (i.e., fewer field goal attempts, assists, steals, turnovers, and points scored), most likely due to greater defensive pressure. Discriminant function analysis correctly classified winning and losing game outcomes during the regular and post-season competitive periods in 82.8% and 87.2% of cases, respectively. …”
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    Game statistics that discriminate winning and losing at the NBA level of basketball competition
  20. 11900
    “…Phenotype prediction and function analysis of the DEPs revealed that three DEPs, particularly Caveolin-1(CAV1), were participated in the regulation of angiogenesis. …”
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    DIA proteomics identified the potential targets associated with angiogenesis in the mammary glands of dairy cows with hemorrhagic mastitis
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