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  1. 11901
    “…Furthermore, pathway function analysis of MetaCYC database implies that the potential mechanism of the response of FMT may be driven by specific bacteria involved in several metabolic pathways that need further exploration. …”
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    Fecal microbiota transplantation treatment for type 1 diabetes mellitus with malnutrition: a case report
  2. 11902
    “…The anti-pulmonary fibrosis of MOBT was evaluated using a MicroCT imaging system for small animals, lung function analysis and H&E and Masson staining. The results of RNA fluorescence in situ hybridization, chromatin immunoprecipitation (ChIP)-PCR, RNA immunoprecipitation, ChIP-seq, RNA-seq, and half-life experiments demonstrated the anti-pulmonary fibrotic mechanism. …”
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    MOBT Alleviates Pulmonary Fibrosis through an lncITPF–hnRNP-l-Complex-Mediated Signaling Pathway
  3. 11903
    “…The results revealed that the prognostic signature had good prognostic performance, even among different clinicopathological subgroups. The function analysis linked CMRGs with KEGG pathway, such as cell adhesion molecules, drug metabolism-cytochrome P450 and other related pathways. …”
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    Establishment and validation of a cholesterol metabolism-related prognostic signature for hepatocellular carcinoma
  4. 11904
    “…Immunofluorescence results indicated PRDX6 translocating between the cytoplasm and cell membrane. Protein function analysis proposed that increased palmitoylation could competitively inhibit the formation of disulfide-bond between Cys47 and Cys91 and change the spatial topology of PRDX6 protein. …”
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    PRDX6: A protein bridging S-palmitoylation and diabetic neuropathy
  5. 11905
    “…Moreover, we verified hub genes and identified potential drugs. 225 common DEGs were identified. Biological function analysis indicated that angiogenesis, cell surface, cell adhesion, extracellular matrix, and focal adhesion genes were enriched among DEGs. …”
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    Exploration of Hub Genes in Retinopathy of Prematurity Based on Bioinformatics Analysis of the Oxygen-Induced Retinopathy Model
  6. 11906
    por Xu, Yan, Liu, Rong
    Publicado 2022
    “…GO enrichment analysis and immune function analysis were performed for the differential genes in the high-risk group and the low-risk group divided by risk score and analyzed the prognostic effect of TMB on the two groups. …”
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    Analysis of the role of m6A and lncRNAs in prognosis and immunotherapy of hepatocellular carcinoma
  7. 11907
    “…Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis and gene function analysis (GO) enrichment analysis were performed using R language to preliminarily explore the multiple pharmacological mechanisms of action of colchicine. …”
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    To discuss the mechanism of colchicine in the treatment of acute cerebral infarction based on network pharmacology
  8. 11908
    “…RESULTS: 8 patients were included in our study, 5 patients responded to quality of life and sexual function analysis. Surgical outcomes were in line with literature: one minor complication (minor dehiscence requiring a skin graft), one major complication (flap loss, requiring a second, contralateral flap) occurred. …”
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    Quality of life and sexual health after perineal reconstruction in Fournier gangrene using pedicled anterolateral thigh flaps
  9. 11909
    “…A virus-induced gene silencing (VIGS) system was established to induce endogenous target gene silencing by post-transcriptional gene silencing (PTGS), which is a powerful tool for gene function analysis in plants. Compared with stable transgenic plant via Agrobacterium-mediated gene transformation, phenotypes after gene knockdown can be obtained rapidly, effectively, and high-throughput through VIGS system. …”
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    Visible gland constantly traces virus-induced gene silencing in cotton
  10. 11910
    “…Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis and gene function analysis (GO) enrichment analysis were performed with the help of Perl language and biological program package in R language. …”
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    Network-based pharmacological study of the mechanism of kaiyuzhongyutang in the treatment of tubal fimbria obstruction
  11. 11911
    “…On the basis of these 81 overlapping genes, enrichment analysis showed the mitochondria played an important role in GTS-mediated MCI pharmacological process. Mitochondrial function analysis showed GTS, protopanaxatriol (PPT), and Rd increased the activities of complex I in a dose-dependent manner. …”
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    Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability
  12. 11912
    “…Left atrial ejection fraction (EF), strain and strain rate of three phases (reservoir, conduit, and pump) and left atrial volume were measured with cardiac function analysis software. (3) Results: Patients with rPA/VSD had decreased maximal volume index (p = 0.008). …”
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    Left Atrial Dysfunction in Children with Repaired Pulmonary Artery Atresia with Ventricular Septal Defect: A Cardiovascular Magnetic Resonance Imaging Study
  13. 11913
    “…Further analysis based on the principal component, subordinate function analysis and clustering methodology revealed that different shading response strategies were adopted by zoysia under shade surroundings. …”
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    Different photosynthetic adaptation of Zoysia spp. under shading: shade avoidance and shade tolerance response
  14. 11914
    “…In a complementary approach, we performed structure-function analysis that identified the C-terminus as important for microdomain localization and likely substrate binding, while N-terminal sequences beyond the known single N-terminal PH-like domain are important for endosome recruitment. …”
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    Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points
  15. 11915
    “…Further, loss-of-function analysis results showed that reduced expression of lasI and rhlI enhanced HR of P. aeruginosa to MEM, AMK, CIP, and CAZ. …”
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    Quorum sensing regulates heteroresistance in Pseudomonas aeruginosa
  16. 11916
    “…In this study, the physiological and biochemical indices of 22 genotypes of S. spontaneum were measured, and the membership function analysis method was used to comprehensively evaluate the cold tolerance ability of these genotypes. …”
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    Cold-Induced Physiological and Biochemical Alternations and Proteomic Insight into the Response of Saccharum spontaneum to Low Temperature
  17. 11917
    “…The studies were carried out with the potentiometry-based Electronic tongue and the data was analysed using Principle Component Analysis, Discriminant Function Analysis, Taste Discrimination Analysis and Soft Independent Modeling of Class Analogy. …”
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    No ambiguity: Chemosensory-based ayurvedic classification of medicinal plants can be fingerprinted using E-tongue coupled with multivariate statistical analysis
  18. 11918
    “…This research provides important technical support for international frontier research fields such as single-cell sequencing, spatial transcriptomics, plant somatic hybridization, gene function analysis and subcellular localization.…”
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    A high-efficiency PEG-Ca(2+)-mediated transient transformation system for broccoli protoplasts
  19. 11919
    “…The step-wise discriminant function analysis revealed two variables that separated the populations significantly. …”
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    Phenotypic divergence and biometric indices of silond catfish, Silonia silondia (Hamilton 1822) populations inhabiting the coastal rivers of Bangladesh
  20. 11920
    “…We performed short hairpin RNA (shRNA)–based loss-of-function analysis of Nmnat2 during mouse retinal development in retinal explant cultures prepared from early (E14.5), middle (E17.5), or late (postnatal day [P]0.5) developmental stages. …”
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    Loss-of-function approach using mouse retinal explants showed pivotal roles of Nmnat2 in early and middle stages of retinal development
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