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  1. 12261
    “…As such, the study generates valuable information for further gene function analysis and identifying candidate genes to improve abiotic stress tolerance in citrus plants.…”
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    Genome-wide identification, characterization, interaction network and expression profile of GRAS gene family in sweet orange (Citrus sinensis)
  2. 12262
    “…We investigated whether hemoglobin (Hb), ferrous ammonium sulfate (FAS) or hemin which contains iron have the detrimental effect on both human brain microvascular endothelial cells and pericytes by cellular function analysis in vitro. We developed an iron (Fe(2+))-detectable probe, Si-RhoNox-1, to investigate intracellular Fe(2+) accumulation (Fe(2+)(intra)). …”
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    Intracellular Fe(2+) accumulation in endothelial cells and pericytes induces blood-brain barrier dysfunction in secondary brain injury after brain hemorrhage
  3. 12263
    “…DCA methods were grouped into three broad categories, depending on output types: (1) transfer function analysis (TFA); (2) autoregulation index (ARI); and (3) correlation coefficient. …”
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    Dynamic Cerebral Autoregulation Reproducibility Is Affected by Physiological Variability
  4. 12264
    “…The expression patterns of CsLBDs in different tissues and their transcription responses to exogenous hormones and abiotic stress were determined by RNA-seq, which showed that CsLBDs may have diverse functions. Analysis of the structural gene promoters revealed that the promoters of CsC4H, CsDFR and CsUGT84A, the structural genes involved in flavonoid biosynthesis, contained LBD recognition binding sites. …”
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    Structural and functional insights into the LBD family involved in abiotic stress and flavonoid synthases in Camellia sinensis
  5. 12265
    “…The protein-protein interaction network was constructed with the STRING database, and the related protein interaction relationship was analysed. GO biological function analysis and KEGG enrichment analysis for core targets were performed. …”
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    Network Pharmacology Approach to Uncover the Mechanism Governing the Effect of Radix Achyranthis Bidentatae on Osteoarthritis
  6. 12266
    “…Routine blood examination, biochemical indicators and coagulation function analysis were simultaneously performed in all participants. …”
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    Using a diagnostic model based on routine laboratory tests to distinguish patients infected with SARS-CoV-2 from those infected with influenza virus
  7. 12267
    “…In silico gain-of-function analysis of the BRAF mutation also implicated involvement of mutation in the process. …”
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    Aberrant expression of the COX2/PGE(2) axis is induced by activation of the RAF/MEK/ERK pathway in BRAF(V595E) canine urothelial carcinoma
  8. 12268
    “…Most of the top-identified miRNAs are verified in the Human MicroRNA Disease Database (HMDD) and are related to breast and liver cancers. Function analysis shows that the top 20 miRNAs regulate multiple cell fate related function modules and interact tightly based on their functional similarity. …”
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    A systematic study of critical miRNAs on cells proliferation and apoptosis by the shortest path
  9. 12269
    “…Statistical analysis of the variables included descriptive statistics, non-parametric Kruskal–Wallis tests, discriminant function analysis (DFA) and a neural classification network. …”
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    Quantitative imagery analysis of spot patterns for the three-haplogroup classification of Triatoma dimidiata (Latreille, 1811) (Hemiptera: Reduviidae), an important vector of Chagas disease
  10. 12270
    “…BACKGROUND: A key issue for implementation of CRISPR-Cas9 genome editing for plant trait improvement and gene function analysis is to efficiently deliver the components, including guide RNAs (gRNAs) and Cas9, into plants. …”
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    Development of a Csy4-processed guide RNA delivery system with soybean-infecting virus ALSV for genome editing
  11. 12271
    “…However, pair distribution function analysis reveals that the local in-layer thiostannate structure of AEPz-SnS-1 remains unchanged. …”
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    Exploring the structures, stability, and light absorption properties of three thiostannates synthesised at similar conditions
  12. 12272
    “…Time lag and transfer function analysis showed that wastewater data preceded clinically reported cases in the first wave of the pandemic but did not serve as a leading indicator in the second wave, likely due to increased testing capacity, which allows for more timely case detection and reporting. …”
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    Metrics to relate COVID-19 wastewater data to clinical testing dynamics
  13. 12273
    “…The discriminant function analysis further revealed that the plasma and urine Wnt5A were separated and distinct for AD SLE patients and healthy controls. …”
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    Correlation of plasma and urine Wnt5A with the disease activity and cutaneous lesion severity in patients with systemic lupus erythematosus
  14. 12274
    “…A recent crystallographic study has disputed this; the Caldalkalibacillus thermarum TA2.A1 F(1)F(o) ATP synthase cannot natively hydrolyse ATP, yet studies have demonstrated that the loss of the ε subunit terminal helix results in an ATP synthase capable of ATP hydrolysis, supporting ε subunit function. Analysis of sequence and crystallographic data of the C. thermarum F(1)F(o) ATP synthase revealed two unique histidine residues. …”
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    ATP binding by an F(1)F(o) ATP synthase ε subunit is pH dependent, suggesting a diversity of ε subunit functional regulation in bacteria
  15. 12275
    “…C498-0670 was predicted to alleviate sepsis/septic shock by disease/function analysis using IPA software, which was further verified in the LPS-induced mouse sepsis model in vivo. …”
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    Bioactive compound C498-0670 alleviates LPS-induced sepsis via JAK/STAT and NFκB signaling pathways
  16. 12276
    “…The optimized cut-off values of AGR and SIRI (AGR = albumin/globulin; SIRI = neutrophil ∗ monocyte/lymphocyte) were determined by survival function analysis based on R software. COX regression analysis was performed to obtain the independent factors for establishing the nomogram model. …”
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    The Prognostic Value and Potential Mechanism of Tumor-Nutrition-Inflammation Index and Genes in Patients with Advanced Lung Cancer
  17. 12277
    “…RESULTS: Finally, 61 essential oil chemical components were identified by GC-MS/MS, which correspond to 679 potential targets. Biological function analysis showed 12, 19, and 12 GO entries related to biological processes, cell components and molecular functions, respectively. 43 KEGG pathways were identified, of which the most significant categories were terpenoid backbone biosynthesis, TNF signaling pathway and leishmaniasis. …”
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    Analysis of Pharmacological Activities and Mechanisms of Essential Oil in Leaves of C. grandis ‘Tomentosa’ by GC-MS/MS and Network Pharmacology
  18. 12278
    por Coss, Richard G., Tyler, Carol Lee
    Publicado 2023
    “…The current research examined the perceptual cues for face recognition by comparing two face models displaying anatomically realistic arrangements of blue iridophores derived from discriminant function analysis of distinct sibling groups. Four groups each consisting of 9 subadults were examined using a narrow compartment restraining lateral movement where face models were presented at eye level for eight trials. …”
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    African jewel fish (Hemichromis bimaculatus) distinguish individual faces based on their unique iridophore patterns
  19. 12279
    “…Differentially expressed genes (DEGs)-affected by IFIT1 gene were screened between the case group and control group, followed by gene function analysis. The clinical diagnostic potential of the least absolute shrinkage and selection operator (LASSO) model, established based on the expression profiles of IFIT1 and IFIFT1-affected DEGs, was evaluated. …”
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    Bioinformatic analysis of immune-related transcriptome affected by IFIT1 gene in childhood systemic lupus erythematosus
  20. 12280
    “…An EGFR signaling-related risk score was established, and a higher score was correlated with poorer prognosis and a more malignant phenotype in gliomas. Biological function analysis revealed that a higher EGFR-related score was significantly associated with various cytokine response pathways, especially IFN-γ. …”
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    The Crosstalk between the EGFR and IFN-γ Pathways and Synergistic Roles in Survival Prediction and Immune Escape in Gliomas
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