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  1. 12441
    “…Sugar beet was relatively resilient to N0.5 stress according to the mean affiliation function analysis. These results provide a theoretical basis for the extensive cultivation of sugar beet in N-stressed soil.…”
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    Acclimation of sugar beet in morphological, physiological and BvAMT1.2 expression under low and high nitrogen supply
  2. 12442
    “…Gene enrichment analysis and immune cell infiltration and immune function analysis were performed using “clusterProfiler” and “GSVA” packages in R. …”
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    Identification of m7G Methylation-Related miRNA Signature Associated with Survival and Immune Microenvironment Regulation in Uterine Corpus Endometrial Carcinoma
  3. 12443
    “…Moreover, we generated MFI in the single-cell dataset, in which cells with high MFI received and sent more signals compared to those with low MFI. Biological function analysis of both subtypes revealed stronger anti-tumor immune activity in the low MFI group, while tumor cells with high MFI had stronger metabolic and proliferative activity. …”
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    Identification and validation of a muscle failure index to predict prognosis and immunotherapy in lung adenocarcinoma through integrated analysis of bulk and single-cell RNA sequencing data
  4. 12444
    “…To investigate whether gut microbiota is involved in IBD-induced Kyn pathway dysregulation, we performed intestinal flora 16S rRNA sequencing and found that DSS-induced colitis significantly altered the composition and diversity of the gut microbiota. Metabolic function analysis also showed that Tryptophan metabolism, NOD-like receptor signaling pathway and MAPK signaling pathway were significantly up-regulated in the 2% DSS group. …”
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    DSS-induced colitis activates the kynurenine pathway in serum and brain by affecting IDO-1 and gut microbiota
  5. 12445
    “…There is a growing trend of using R for clinical trial analysis and reporting as part of regulatory submissions, where R functions, analysis scripts, analysis results, and all proprietary code dependencies are required to be included. …”
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    Electronic common technical document submission with analysis using R
  6. 12446
    “…In discriminant function analysis for Class II subjects, the classification accuracy was 98.4%, whereas subsequent to cross-validation, the classification accuracy was 90.6%. …”
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    Soft-Tissue Analysis of Different Sagittal Skeletal Patterns Using the Geometric Morphometric Method
  7. 12447
    “…During HUD examination, software-derived LV function analysis failed to measure LVEF in 29 (46%) cases. …”
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    Integrated Assessment of Heart, Lung and Lower Extremity Veins Using Hand-Held Ultrasound Device in COVID-19 Patients: Feasibility and Clinical Application
  8. 12448
    “…METHODS: We downloaded the public transcriptome data (GSE37587) from the gene expression omnibus and divided the patients into young and old groups and identified differentially expressed genes (DEGs). Gene ontology function analysis, Kyoto encyclopedia of genes and genomes pathway analysis, and gene set enrichment analysis (GSEA) were performed. …”
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    Identification microenvironment immune features and key genes in elderly stroke patients
  9. 12449
    “…We profiled the differentially expressed genes and identified a group of RNA-binding proteins (RBPs) as potential regulators. Gene function analysis indicated that most of these genes were enriched in RNA-regulated pathways including RNA processing. …”
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    RNA binding proteins are potential novel biomarkers of egg quality in yellow catfish
  10. 12450
    “…Linear discriminant analysis (LDA) effect size (LEfSe) analysis revealed representative microbial markers of Lachnospiraceae_bacterium_BX3, Massilioclostridium_coli, TM7_phylum_sp_oral_taxon_348 and Bacteroides_fragilis for patients with vitiligo. KEGG gene function analysis showed that the NOD-like receptor signaling pathway was significantly enriched in patients with vitiligo. …”
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    Metagenomic sequencing reveals altered gut microbial compositions and gene functions in patients with non-segmental vitiligo
  11. 12451
    “…To further explore this novel signature, pathway and function analysis was performed, and differences in gene mutation frequency between high- and low-risk groups were studied. …”
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    Leveraging a disulfidptosis/ferroptosis-based signature to predict the prognosis of lung adenocarcinoma
  12. 12452
    “…CONCLUSIONS: The results of this study provide useful information for GATA gene function analysis and aid in the understanding of stress responses in grapevine for future molecular breeding initiatives. …”
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    Analysis of GATA transcription factors and their expression patterns under abiotic stress in grapevine (Vitis vinifera L.)
  13. 12453
    por Scirè, Carlo A., Carrara, Greta, Viroli, Cinzia, Cimmino, Marco A., Taylor, William J., Manara, Maria, Govoni, Marcello, Salaffi, Fausto, Punzi, Leonardo, Montecucco, Carlomaurizio, Matucci‐Cerinic, Marco, Minisola, Giovanni, Ariani, Alarico, Galossi, Alessandra, Lauriti, Ciro, Fracassi, Elena, Idolazzi, Luca, Bardelli, Marco, Selvi, Enrico, Tirri, Enrico, Furini, Federica, Inverardi, Flora, Calabrò, Andrea, Porta, Francesco, Bittelli, Raffaele, Venturino, Francesco, Capsoni, Franco, Prevete, Immacolata, Sebastiani, Giandomenico, Selmi, Carlo, Fabbriciani, Gianluigi, D'Avola, Giovanni, Botticella, Giulia, Serale, Francesca, Seminara, Giulia, D'Alessandro, Giuseppe, Santo, Leonardo, Longato, Lorena, Zaccara, Eleonora, Sinigaglia, Luigi, Atteritano, Marco, Broggini, Marco, Caprioli, Marta, Favero, Marta, Sallì, Salvatore, Scarati, Marco, Parisi, Simone, Malavolta, Nazzarena, Corvaglia, Stefania, Scarpato, Salvatore, Veneto, Vittorio
    Publicado 2016
    “…RESULTS: Factor analysis identified 5 factors: patient‐reported outcomes, joint examination, flares, tophi, and serum uric acid (sUA). Discriminant function analysis resulted in a correct classification of 79%. …”
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    Development and First Validation of a Disease Activity Score for Gout
  14. 12454
    “…Besides, overexpression of UBQLN4 was associated with poor overall survival and disease-free survival rate of HCC patients. The loss-of-function analysis revealed that suppression of UBQLN4 inhibited the proliferation and invasion of HCC cells in vivo and in vitro. …”
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    UBQLN4 promotes progression of HCC via activating wnt-β-catenin pathway and is regulated by miR-370
  15. 12455
    “…RESULTS: Discriminant function analysis revealed low levels of CSF t-α-syn, high levels of CSF o-α-syn and TNF-α best discriminated asymptomatic LRRK2 mutation carriers from both symptomatic PD and healthy controls. …”
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    CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers
  16. 12456
    “…Furthermore, a gene function analysis was used to explore molecular mechanisms that might affect cancer development. …”
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    An improved clear cell renal cell carcinoma stage prediction model based on gene sets
  17. 12457
    por Sonnweber, Thomas, Sahanic, Sabina, Pizzini, Alex, Luger, Anna, Schwabl, Christoph, Sonnweber, Bettina, Kurz, Katharina, Koppelstätter, Sabine, Haschka, David, Petzer, Verena, Boehm, Anna, Aichner, Magdalena, Tymoszuk, Piotr, Lener, Daniela, Theurl, Markus, Lorsbach-Köhler, Almut, Tancevski, Amra, Schapfl, Anna, Schaber, Marc, Hilbe, Richard, Nairz, Manfred, Puchner, Bernhard, Hüttenberger, Doris, Tschurtschenthaler, Christoph, Aßhoff, Malte, Peer, Andreas, Hartig, Frank, Bellmann, Romuald, Joannidis, Michael, Gollmann-Tepeköylü, Can, Holfeld, Johannes, Feuchtner, Gudrun, Egger, Alexander, Hoermann, Gregor, Schroll, Andrea, Fritsche, Gernot, Wildner, Sophie, Bellmann-Weiler, Rosa, Kirchmair, Rudolf, Helbok, Raimund, Prosch, Helmut, Rieder, Dietmar, Trajanoski, Zlatko, Kronenberg, Florian, Wöll, Ewald, Weiss, Günter, Widmann, Gerlig, Löffler-Ragg, Judith, Tancevski, Ivan
    Publicado 2021
    “…We conducted a detailed questionnaire, clinical examination, laboratory testing, lung function analysis, echocardiography and thoracic low-dose computed tomography (CT). …”
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    Cardiopulmonary recovery after COVID-19: an observational prospective multicentre trial
  18. 12458
    “…Blood was collected for liver function analysis while the liver was obtained for histopathological examination and endogenous antioxidant activity determination. …”
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    Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat
  19. 12459
    “…Metrics were also reconstructed at internal nodes of the lemur tree and these reconstructions were combined to generate dietary classification probabilities at internal nodes using discriminant function analysis. We used these reconstructions to calculate rates of transition toward folivory per million-year intervals. …”
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    Insights from macroevolutionary modelling and ancestral state reconstruction into the radiation and historical dietary ecology of Lemuriformes (Primates, Mammalia)
  20. 12460
    “…Gain or loss of function analysis reveals that Xist accelerates oocyte autophagy, mainly through binding to pre-miR-23b or pre-miR-29a in the nucleus and preventing the export of pre-miR-23b/pre-miR-29a to the cytoplasm, thus resulting in decreased mature of miR-23b-3p/miR-29a-3p expression and upregulation miR-23b-3p/miR-29a-3p co-target, STX17, which is essential for timely control of the degree of oocyte death in prenatal mouse ovaries. …”
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    Long non-coding RNA Xist regulates oocyte loss via suppressing miR-23b-3p/miR-29a-3p maturation and upregulating STX17 in perinatal mouse ovaries
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