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Análisis funcional
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Climatic variables influence annual P. montezumae growth
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12601por Cruz, Daryl D., Arellano, Elizabeth, Denis Ávila, Dennis, Ibarra-Cerdeña, Carlos N.“…A linear discriminant function analysis and an ordination plot of the discriminant analysis were performed using the shape variables. …”
Publicado 2020
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12602por Singh, Dave, Emirova, Aida, Francisco, Catherine, Santoro, Debora, Govoni, Mirco, Nandeuil, Marie Anna“…CONCLUSIONS: CHF6001 had no effect in the primary lung function analysis, although was well-tolerated with no gastrointestinal adverse event signal. …”
Publicado 2020
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12603por Shin, Kyung Min, Choi, Jiwoong, Chae, Kum Ju, Jin, Gong Yong, Eskandari, Ali, Hoffman, Eric A., Hall, Chase, Castro, Mario, Lee, Chang Hyun“…Non-rigid image registration-based inspiratory-expiratory image matching assessment was used for regional lung function analysis. Tissue fractions (TF) were computed based on the CT density and compared on a lobar basis. …”
Publicado 2020
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12604por Zhao, Xingwang, Zhang, Longlong, Wang, Juan, Zhang, Min, Song, Zhiqiang, Ni, Bing, You, Yi“…RESULTS: In total, 6 DEGs (IFI27, IFI44, IFI44L, IFI6, EPSTI1 and OAS1) were screened, Biological functions analysis identified key related pathways, gene modules and co‐expression networks in SLE. …”
Publicado 2021
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12605por Dai, Yun, Sun, Xiao, Wang, Chenggang, Li, Fei, Zhang, Shifan, Zhang, Hui, Li, Guoliang, Yuan, Lingyun, Chen, Guohu, Sun, Rifei, Zhang, Shujiang“…Comparative transcriptome analysis and weighted gene co-expression network analysis (WGCNA) were performed for different-bolting Chinese cabbage during different vernalization periods. The biological function analysis and hub gene annotation of highly relevant modules revealed that shoot system morphogenesis and polysaccharide and sugar metabolism caused early-bolting ‘XBJ’ to bolt and flower faster; chitin, ABA and ethylene-activated signaling pathways were enriched in late-bolting ‘JWW’; and leaf senescence and carbohydrate metabolism enrichment were found in the two Chinese cabbage-related modules, indicating that these pathways may be related to bolting and flowering. …”
Publicado 2021
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12606por Su, Yuan, Xu, Yang, Cui, Tao, Gao, Xiaojun, Xia, Guoyi, Li, Yibo, Qiao, Mengmeng, Yu, Yingbo“…Considering that the mechanical properties of kernels vary greatly as the moisture content changes, a subsection linear (average goodness of fit is 0.9) to predict the threshing quality is built by piecewise function analysis, which is divided by kernel moisture. …”
Publicado 2021
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12607por Ma, Gang, Li, Guichen, Fan, Wufeng, Xu, Yuanhong, Song, Shaowei, Guo, Kejian, Liu, Zhe“…Gain- and loss-of-function analysis showed that circ-0005105 facilitated both in vitro and in vivo cellular proliferation and invasion. …”
Publicado 2021
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12608por Cerutti, Gabriele, Gugole, Elena, Montemiglio, Linda Celeste, Turbé-Doan, Annick, Chena, Dehbia, Navarro, David, Lomascolo, Anne, Piumi, François, Exertier, Cécile, Freda, Ida, Vallone, Beatrice, Record, Eric, Savino, Carmelinda, Sciara, Giuliano“…CONCLUSIONS: Structure–function analysis of ODH is consistent with its role as an auxiliary enzyme in lignocellulose degradation and unveils yet another enzymatic function within the AA3 family of the Carbohydrate-Active enZymes database. …”
Publicado 2021
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12609por Vieira-Lara, Marcel A., Dommerholt, Marleen B., Zhang, Wenxuan, Blankestijn, Maaike, Wolters, Justina C., Abegaz, Fentaw, Gerding, Albert, van der Veen, Ydwine T., Thomas, Rachel, van Os, Ronald P., Reijngoud, Dirk-Jan, Jonker, Johan W., Kruit, Janine K., Bakker, Barbara M.“…To gain insights into the interplay of diet and age in the flexibility of muscle lipid and glucose handling, we combined lipidomics, proteomics, mitochondrial function analysis and computational modelling to investigate young and aged mice on a low- or high-fat diet (HFD). …”
Publicado 2021
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12610por Cheng, Chunzhen, Liu, Fan, Tian, Na, Mensah, Raphael Anue, Sun, Xueli, Liu, Jiapeng, Wu, Junwei, Wang, Bin, Li, Dan, Lai, Zhongxiong“…Totally, 12,109 lncRNAs, 36,519 mRNAs and 2642 novel genes were obtained, of which 1398 (including 78 DELs, 1220 DE known genes and 100 DE novel genes) were identified as FocTR4 responsive DE transcripts. Gene function analysis revealed that most DEGs were involved in biosynthesis of secondary metabolites, plant–pathogen interaction, plant hormone signal transduction, phenylalanine metabolism, phenylpropanoid biosynthesis, alpha-linolenic acid metabolism and so on. …”
Publicado 2021
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12611por Wu, Xiaohong, Zhou, Yanxia, Qi, Wenwei, Shen, Yanxia, Lei, Zhihao, Xiao, Kun, Zhang, Pandeng, Liu, Jia, Ren, Lijie“…Within 7 days after stroke onset, CA was recorded from the middle cerebral artery blood flow velocity and arterial blood pressure was simultaneously measured. Transfer function analysis was used to derive CA parameters, including gain and phase. …”
Publicado 2022
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12612por Haro-Luna, Mara Ximena, Blancas Vázquez, José, Ruan-Soto, Felipe, Guzmán-Dávalos, Laura“…With the data obtained, we performed linear regression tests and principal components analysis (PCA); furthermore, the significance of the groupings obtained by PCA was tested with a discriminant function analysis. RESULTS: We find that TMK was determined by the cultural group to which a person belongs. …”
Publicado 2022
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12613por Shandilya, Umesh K., Wu, Xiang, McAllister, Caitlin, Mutharia, Lucy, Karrow, Niel A.“…The expression of miRNAs (miR133b, miR-92a, and miR-184) was increased in WT MAC-T cells post-MAP infection; however, there was no significant induction of these miRNAs in TLR4KO cells, which suggests they are involved in regulating the innate immune response to MAP infection. Target gene function analysis further suggests that miR-92a may be involved in TLR and interleukin signaling and miR-133b and miR-184 may be involved in other signaling pathways. …”
Publicado 2023
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12614por Hu, Yan, Gao, Peng, Xu, Gaoqi, Sun, Jiao, Xin, Wenxiu, Kong, Sisi, Ding, Haiying, Zhu, Junfeng, Fang, Luo“…In pan-pathway analysis, the cell lines showing the highest genetic correlation to patient tumors were Panc 03.27 for PAAD cell lines from a primary lesion site and CFPAC-1 for PAAD cell lines from a metastatic lesion site. In pan-function analysis, the cell lines showing the highest genetic correlation to patient tumors were Panc 03.27 for PAAD cell lines from a primary lesion site and Capan-1 for PAAD cell lines from a metastatic lesion site. …”
Publicado 2023
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12615por Liang, Xiaonan, Li, Chenyang, Song, Jia, Liu, Airu, Wang, Chen, Wang, Wenxin, Kang, Yaxing, Sun, Donglei, Qian, Jiaming, Zhang, Xiaolan“…The intestinal organoid model of IBD was constructed utilizing tumor necrosis factor (TNF)-α for subsequent function analysis in vitro. Transcriptome sequencing was performed to decipher the underlying mechanism and Wnt-C59, an oral Wnt inhibitor, was used to confirm that further. …”
Publicado 2023
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12616por Ge, Jing, Liu, Sheng-Lu, Zheng, Jing-Xiu, Shi, Yu, Shao, Ying, Duan, Yu-Jing, Huang, Rui, Yang, Li-Jun, Yang, Tao“…Then, how ALKBH5 affects the biological behaviors of CRC cells were confirmed by gain- and loss-of-function analysis. Furthermore, the relationship between ALKBH5 level and 22 tumor-infiltrating immune cells was examined through CIBERSORT in R software. …”
Publicado 2023
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12617“…Conversely, in genes with type II AFEs, the first exon of one gene structure is an internal exon of an alternative gene structure. The functionality analysis indicated about half and ~19% of the AFEs in Arabidopsis and rice could alter N-terminal protein sequences, and ~5% of the functional alteration in type II AFEs involved protein domain addition/deletion in both genomes. …”
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12618por Kunz, Dieter, Walker, Gaby, Bedoucha, Marc, Certa, Ulrich, März-Weiss, Pia, Dimitriades-Schmutz, Beatrice, Otten, Uwe“…Ingenuity biological function analysis revealed that completely different repertoires of molecules are recruited to exert the same biological functions in neuronal differentiation. …”
Publicado 2009
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12619por Kiviluoto, Santeri, Decuypere, Jean-Paul, De Smedt, Humbert, Missiaen, Ludwig, Parys, Jan B, Bultynck, Geert“…STIM proteins target Orai1-3, tetrameric Ca(2+)-permeable channels in the plasma membrane. Structure-function analysis revealed the molecular determinants and the key steps in the activation process of Orai by STIM. …”
Publicado 2011
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12620“…This method could also be used for targeted delivery of other reagents including short-hairpin RNA interference expression plasmids, which would provide a method for spatially and temporally discrete loss-of-function analysis.…”
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