-
1661por Kasse, Yaya, Jasseh, Momodou, Corrah, Tumani, Donkor, Simon A, Antonnio, Martin, Jallow, Adama, Adegbola, Richard A, Hill, Philip C“…We aimed to study health-seeking behaviour and experience of those with cough in The Gambia and to identify whether they had tuberculosis. …”
Publicado 2006
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1662por Natividad, Angels, Cooke, Graham, Holland, Martin J, Burton, Matthew J, Joof, Hassan M, Rockett, Kirk, Kwiatkowski, Dominic P, Mabey, David CW, Bailey, Robin L“…METHODS: We genotyped 651 case-control pairs from trachoma endemic villages in The Gambia for coding single nucleotide polymorphisms (SNPs) in the MMP9 gene using the high-throughput Sequenom(® )system. …”
Publicado 2006
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1663por Smith, Helen, Bukirwa, Hasifa, Mukasa, Oscar, Snell, Paul, Adeh-Nsoh, Sylvester, Mbuyita, Selemani, Honorati, Masanja, Orji, Bright, Garner, Paul“…METHODS: Descriptive study in four teaching hospitals in Cameroon, Nigeria, Tanzania and Uganda plus one externally funded research institution in The Gambia. Survey with postgraduate doctors and research scientists to determine Internet access patterns, reported awareness of on-line medical information and free access initiatives; semi structured interviews with a sub-sample of survey participants to explore factors influencing use. …”
Publicado 2007
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1664por Mangano, Valentina D., Clark, Taane G., Auburn, Sarah, Campino, Susana, Diakite, Mahamadou, Fry, Andrew E., Green, Angela, Richardson, Anna, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Griffiths, Michael J., Newton, Charles, Peshu, Norbert, Williams, Thomas N., Marsh, Kevin, Molyneux, Malcolm E., Taylor, Terrie E., Modiano, David, Kwiatkowski, Dominic P., Rockett, Kirk A.“…In order to test whether genetic variation at the IRF1 locus also affects the risk of developing severe malaria, we performed a family-based test of association for 18 Single Nucleotide Polymorphisms (SNPs) across the gene in three African populations, using genotype data from 961 trios consisting of one affected child and his/her two parents (555 from The Gambia, 204 from Kenya and 202 from Malawi). No significant association with severe malaria or severe malaria subphenotypes (cerebral malaria and severe malaria anaemia) was observed for any of the SNPs/haplotypes tested in any of the study populations. …”
Publicado 2009
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1665por Uthman, Olalekan A“…Uganda, Zimbabwe and Malawi had better records when the total production was adjusted for gross domestic product (GDP). Comoros, the Gambia and Guinea-Bissau were the most productive countries when the total products were normalized by number of people with HIV. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1666por Savy, Mathilde, Hennig, Branwen J., Doherty, Conor P., Fulford, Anthony J., Bailey, Robin, Holland, Martin J., Sirugo, Giorgio, Rockett, Kirk A., Kwiatkowski, Dominic P., Prentice, Andrew M., Cox, Sharon E.“…CONCLUSIONS: These data indicate that genetic variation in Hp may affect susceptibility to active trachoma differentially by sex in The Gambia.…”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1667por Jobarteh, Modou, Malfroy, Marine, Peterson, Ingrid, Jeng, Adam, Sarge-Njie, Ramu, Alabi, Abraham, Peterson, Kevin, Cotten, Matt, Hall, Andrew, Rowland-Jones, Sarah, Whittle, Hilton, Tedder, Richard, Jaye, Assan, Mendy, Maimuna“…OBJECTIVE: The aim of this study is to determine the seroprevalence of HBV and HCV virus in HIV-infected subjects in the Gambia. METHODS: Plasma samples from HIV infected patients (190 individuals with clinically defined AIDS and 382 individuals without AIDS) were tested retrospectively for the presence of HBV sero-markers and for serum HBV DNA, screened for HCV infection by testing for anti-HCV antibody and HCV RNA. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1668por Sutherland, Jayne S., Hill, Philip C., Adetifa, Ifedayo M., de Jong, Bouke C., Donkor, Simon, Joosten, Simone A., Opmeer, Lizet, Haks, Marielle C., Ottenhoff, Tom H. M., Adegbola, Richard A., Ota, Martin O. C.“…This study provides the first comprehensive analysis of the immune system of progressors and non-progressors using a well-characterised TB case-contact (TBCC) platform in The Gambia, West Africa. 22 progressors and 31 non-progressors were analysed at recruitment, 3 months and 18 months (time to progression: median[IQR] of 507[187–714] days). …”
Publicado 2011
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1669por Velez Edwards, Digna R., Tacconelli, Alessandra, Wejse, Christian, Hill, Philip C., Morris, Gerard A. J., Edwards, Todd L., Gilbert, John R., Myers, Jamie L., Park, Yo Son, Stryjewski, Martin E., Abbate, Eduardo, Estevan, Rosa, Rabna, Paulo, Novelli, Giuseppe, Hamilton, Carol D., Adegbola, Richard, Østergaard, Lars, Williams, Scott M., Scott, William K., Sirugo, Giorgio“…We examined eight MCP1 single nucleotide polymorphisms (SNPs) in a multi-ethnic, case-control design that included: 321 cases and 346 controls from Guinea-Bissau, 258 cases and 271 controls from The Gambia, 295 cases and 179 controls from the U.S. (African-Americans), and an additional set of 237 cases and 144 controls of European ancestry from the U.S. and Argentina. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1670por Dicks, Matthew D. J., Spencer, Alexandra J., Edwards, Nick J., Wadell, Göran, Bojang, Kalifa, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.“…Furthermore, the prevalence of virus neutralizing antibodies (titre >1∶200) against ChAdY25 in serum samples collected from two human populations in the UK and Gambia was particularly low compared to published data for other chimpanzee adenoviruses. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1671“…GEMS, which includes one of the largest case/control studies of an infectious disease syndrome ever undertaken (target approximately 12 600 analyzable cases and 12 600 controls), was rolled out in 4 sites in sub-Saharan Africa (Gambia, Kenya, Mali, Mozambique) and 3 in South Asia (Bangladesh, India, Pakistan), with each site linked to a population under demographic surveillance (total approximately 467 000 child years of observation among children <5 years of age). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1672“…METHODS: Seventy three invasive and carriage S. pneumoniae isolates from three West African countries including The Gambia, Nigeria and Ghana were investigated. The isolates covered seven serotypes (1, 3, 5, 6A, 11, 14, 23F) and were subjected to multilocus sequence typing and antibiotic susceptibility testing. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1673por Abdulmalik, Jibril, Fadahunsi, Woye, Kola, Lola, Nwefoh, Emeka, Minas, Harry, Eaton, Julian, Gureje, Oye“…Launched in 2010 to serve the Anglophone countries of The Gambia, Ghana, Liberia, Nigeria, Sierra Leone, this paper describes the components of the program, the experience gained since its initiation, and the achievements made during the three years of its implementation. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1674“…The importance of these differences is described in detail between select ethnic groups, within the USA between African-Americans and White-Americans, between the Gambia and the UK and between China and the UK. Dietary Ca intake is higher in White-Americans compared with African-Americans, and is higher in White-British compared with Gambian and Chinese adults. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1675por Fossette, S., Witt, M. J., Miller, P., Nalovic, M. A., Albareda, D., Almeida, A. P., Broderick, A. C., Chacón-Chaverri, D., Coyne, M. S., Domingo, A., Eckert, S., Evans, D., Fallabrino, A., Ferraroli, S., Formia, A., Giffoni, B., Hays, G. C., Hughes, G., Kelle, L., Leslie, A., López-Mendilaharsu, M., Luschi, P., Prosdocimi, L., Rodriguez-Heredia, S., Turny, A., Verhage, S., Godley, B. J.“…International collaborative efforts are needed, especially from nations hosting regions where susceptibility to bycatch is likely to be high within their exclusive economic zone (northern Atlantic: Cape Verde, Gambia, Guinea Bissau, Mauritania, Senegal, Spain, USA and Western Sahara; southern Atlantic: Angola, Brazil, Namibia and UK) and from nations fishing in these high-susceptibility areas, including those located in international waters.…”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1676por Williams, Caroline M. L., Cheah, Eddy S. G., Malkin, Joanne, Patel, Hemu, Otu, Jacob, Mlaga, Kodjovi, Sutherland, Jayne S., Antonio, Martin, Perera, Nelun, Woltmann, Gerrit, Haldar, Pranabashis, Garton, Natalie J., Barer, Michael R.“…In series 2, 19 patients with suspected tuberculosis were studied in Leicester UK and 10 patients with at least one positive smear were studied in The Gambia. These subjects wore one FFP30 mask modified to contain a gelatin filter for one hour; this was subsequently analyzed by the Xpert MTB/RIF system. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1677por Burr, Sarah E, Hart, John, Edwards, Tansy, Harding-Esch, Emma M, Holland, Martin J, Mabey, David C W, Sillah, Ansumana, Bailey, Robin L“…CONCLUSIONS: Our data do not provide evidence that community MDA with azithromycin improved anthropometric outcomes of children in The Gambia. This may suggest reductions in mortality associated with azithromycin MDA are due to a mechanism other than improved nutritional status.…”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1678por Zhou, Yanjiao, Holland, Martin J, Makalo, Pateh, Joof, Hassan, Roberts, Chrissy h, Mabey, David CW, Bailey, Robin L, Burton, Matthew J, Weinstock, George M, Burr, Sarah E“…METHODS: We used deep sequencing of the V1-V3 region of the bacterial 16S rRNA gene to characterize the microbiome of the conjunctiva of 220 residents of The Gambia, 105 with healthy conjunctivae and 115 with clinical signs of trachoma in the absence of detectable C. trachomatis infection. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1679por Bottomley, Christian, Bojang, Abdoulie, Smith, Peter G, Darboe, Ousainou, Antonio, Martin, Foster-Nyarko, Ebenezer, Kampmann, Beate, Greenwood, Brian, D’Alessandro, Umberto, Roca, Anna“…METHODS: A cohort of children from rural Gambia was recruited at birth and followed up for one year. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1680por Daya, Michelle, van der Merwe, Lize, van Helden, Paul D., Möller, Marlo, Hoal, Eileen G.“…We attempt to validate the top models identified in our discovery data set using an independent genome-wide TB case-control data set from The Gambia. A number of models were successfully validated, indicating that interplay between the NRG1 - NRG3, GRIK1 - GRIK3 and IL23R - ATG4C gene pairs may modify susceptibility to TB. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto