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426281por Kapetanovic, Meliha C, Kristensen, Lars-Erik, Saxne, Tore, Aktas, Teodora, Mörner, Andreas, Geborek, Pierre“…Antibody titers 3 to 6 months after vaccination was generally lower compared to those within the first 3 months but no further decrease in titers were observed 6 to 22 months after vaccination. …”
Publicado 2014
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426282por Rahaman, Ahibur, Ghosh, Shishir, Unwin, David G., Basak-Modi, Sucharita, Holt, Katherine B., Kabir, Shariff E., Nordlander, Ebbe, Richmond, Michael G., Hogarth, Graeme“…Each undergoes a quasi-reversible oxidation, the potential of which is sensitive to phosphine substitution, generally occurring between 0.15 and 0.50 V, although [Fe(3)(CO)(5)(PPh(3))(2)(μ-edt)(2)] is oxidized at −0.05 V. …”
Publicado 2014
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426283por Paanalahti, Kari, Holm, Lena W, Nordin, Margareta, Asker, Martin, Lyander, Jessica, Skillgate, Eva“…Adverse events were measured with a questionnaire after each return visit and categorized in to five levels; 1) short minor, 2) long minor, 3) short moderate, 4) long moderate and 5) serious adverse events, based on the duration and/or severity of the event. Generalized estimating equations were used to examine the association between adverse event and treatments arms. …”
Publicado 2014
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426284por Chan, Siu Ling, Cheung, Kenneth MC, Luk, Keith DK, Wong, Kenneth WH, Wong, Man Sang“…To identify the relationship among these three areas, logistic regression model and generalized linear model were used. RESULT: For the compliance measure, a significant difference (p = 0.008) was detected on TAPS mean score difference between Visit 1 and Visit 2 in the least compliant group (0–8 hours) and the most compliant group (17–23 hours). …”
Publicado 2014
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426285por Cunha, Cynthia Braga, De Boni, Raquel Brandini, Guimarães, Maria Regina Cotrim, Yanavich, Carolyn, Veloso, Valdilea Gonçalves, Moreira, Ronaldo Ismerio, Hoagland, Brenda, Grinsztejn, Beatriz, Friedman, Ruth Khalili“…The one hundred and fifty five MSM included in the study answered an ACASI interview and provided biological samples. Generalized linear models were used to identify variables associated with UAI. …”
Publicado 2014
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426286por Onishi, Hiroshi, Kawasaki, Tomonori, Zakoji, Hidenori, Yoshida, Takashi, Komiyama, Takafumi, Kuriyama, Kengo, Araya, Masayuki, Saito, Ryo, Aoki, Shinichi, Maehata, Yoshiyasu, Tominaga, Licht, Marino, Kan, Watanabe, Iori, Oguri, Mitsuhiko, Araki, Tsutomu, Enomoto, Nobuyuki, Takeda, Masayuki, Katoh, Ryohei“…BACKGROUND: Treatment of primary renal cell carcinoma using radiotherapy with curative intent is rare, because renal cell carcinoma is generally regarded as a radiation-resistant tumor. …”
Publicado 2014
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426287por Geiser, Marianne, Stoeger, Tobias, Casaulta, Marco, Chen, Shanze, Semmler-Behnke, Manuela, Bolle, Ines, Takenaka, Shinji, Kreyling, Wolfgang G, Schulz, Holger“…Anti-inflammatory 15-hydroxyeicosatetraenoic acid was generally significantly lower in BAL of Cftr mutant than in wild type mice. …”
Publicado 2014
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426288por Voong, Khinh Ranh, McSpadden, Kelli, Pinnix, Chelsea C, Shihadeh, Ferial, Reed, Valerie, Salehpour, Mohammad R, Arzu, Isidora, Wang, He, Hodgson, David, Garcia, John, Aristophanous, Michalis, Dabaja, Bouthaina S“…RESULTS: Use of IMRT generally reduced the V(30) and V(20) to critical structures: −1.4% and +0.1% to the right breast, −1.7% and −0.9% to the left breast, −14.6% and −7.7% to the total lung, −12.2% and −10.5% to the heart, −2.4% and −14.2% to the left ventricle, −16.4% and −8.4% to the right ventricle, −7.0% and −14.2% to the LAD, and −52.2% and −13.4% to the spinal cord. …”
Publicado 2014
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426289por Peck, Robert, Mghamba, Janneth, Vanobberghen, Fiona, Kavishe, Bazil, Rugarabamu, Vivian, Smeeth, Liam, Hayes, Richard, Grosskurth, Heiner, Kapiga, Saidi“…Ten (42%) facilities had guidelines for HIV whereas three (13%) facilities did for NCDs. 261 (78%) health workers showed fair knowledge of HIV, whereas 198 (59%) did for hypertension and 187 (56%) did for diabetes. Generally, health systems were weaker in lower-level facilities. …”
Publicado 2014
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426290por Sinclair, Alan, Bode, Bruce, Harris, Stewart, Vijapurkar, Ujjwala, Mayer, Cristiana, Fung, Albert, Shaw, Wayne, Usiskin, Keith, Desai, Mehul, Meininger, Gary“…CONCLUSIONS: Canagliflozin improved glycaemic control, body weight, and systolic BP, and was generally well tolerated in older patients with T2DM. …”
Publicado 2014
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426291por Meininger, Vincent, Pradat, Pierre-François, Corse, Andrea, Al-Sarraj, Safa, Rix Brooks, Benjamin, Caress, James B., Cudkowicz, Merit, Kolb, Stephen J., Lange, Dale, Leigh, P. Nigel, Meyer, Thomas, Milleri, Stefano, Morrison, Karen E., Orrell, Richard W., Peters, Gary, Rothstein, Jeffrey D., Shefner, Jeremy, Lavrov, Arseniy, Williams, Nicola, Overend, Phil, Price, Jeffrey, Bates, Stewart, Bullman, Jonathan, Krull, David, Berges, Alienor, Abila, Bams, Meno-Tetang, Guy, Wurthner, Jens“…One subject (repeat dose 15 mg/kg ozanezumab) showed a weak, positive anti-ozanezumab-antibody result. PK results were generally consistent with monoclonal antibody treatments. …”
Publicado 2014
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426292“…UMEC was rapidly absorbed following inhaled dosing and eliminated from plasma. Adverse events, generally mild, were highest with UMEC 125 μg QD (18%) compared with placebo (8%), tiotropium (4%) and other UMEC doses (5–12%). …”
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426293por Udyavar, Akshata R, Hoeksema, Megan D, Clark, Jonathan E, Zou, Yong, Tang, Zuojian, Li, Zhiguo, Li, Ming, Chen, Heidi, Statnikov, Alexander, Shyr, Yu, Liebler, Daniel C, Field, John, Eisenberg, Rosana, Estrada, Lourdes, Massion, Pierre P, Quaranta, Vito“…Differential gene expression analysis has also produced SCLC signatures with limited application, since they are generally not robust across datasets. Nonetheless, additional genomic approaches are warranted, due to the increasing availability of suitable small-cell lung cancer datasets. …”
Publicado 2013
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426294por Burge, Fred, Lawson, Beverley, Johnston, Grace, Asada, Yukiko, McIntyre, Paul F, Grunfeld, Eva, Flowerdew, Gordon“…CONCLUSION: Bereaved informants were generally highly satisfied with the decedent's care during their last 30 days but variations were evident. …”
Publicado 2014
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426295“…OBJECTIVE: To evaluate the efficacy, tolerability, and safety of once-daily 1200 mg and 2400 mg SPN-804 (Oxtellar XR™, Supernus Pharmaceuticals), an extended-release tablet formulation of oxcarbazepine (OXC), added to 1-3 concomitant antiepileptic drugs (AEDs) in adults with refractory partial-onset seizures, with or without secondary generalization. METHODS: The Prospective, Randomized Study of OXC XR in Subjects with Partial Epilepsy Refractory (PROSPER) study was a multinational, randomized, double-blind, parallel-group Phase 3 study. …”
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426296por Tarral, Antoine, Blesson, Séverine, Mordt, Olaf Valverde, Torreele, Els, Sassella, Daniela, Bray, Michael A., Hovsepian, Lionel, Evène, Eric, Gualano, Virginie, Felices, Mathieu, Strub-Wourgaft, Nathalie“…Fourteen-day multiple ascending dosing administered up to 3,600 mg/day in fasted conditions showed that fexinidazole was generally well-tolerated (mild to moderate, spontaneously reversible drug-related adverse events). …”
Publicado 2014
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426297por Golubic, Rajna, Martin, Kathryn R, Ekelund, Ulf, Hardy, Rebecca, Kuh, Diana, Wareham, Nicholas, Cooper, Rachel, Brage, Soren“…Our findings suggest PA levels are generally low and observed patterns of variation indicate specific subgroups who might benefit from targeted interventions to increase PA.…”
Publicado 2014
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426298“…The linear relationships between loci found in the present map and in previously compiled physical maps were presented, which were generally in accordance. Information on the genetic and physical positions and allele sizes (when possible) of 17 DArT, 50 e-SSR, 44 SRAP, five ISSR, and two morphological markers is reported here for the first time. …”
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426299“…We used a multivariable generalized linear model regression analysis with a log link to estimate the relative risk (RR) of independent factors on retention. …”
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426300por Li, Siming, Kong, Yan, Si, Lu, Chi, Zhihong, Cui, Chuanliang, Sheng, Xinan, Guo, Jun“…Everolimus (RAD001), a new inhibitor for mammalian target of rapamycin (mTOR), is generally well tolerated, and demonstrates clinical benefit to patients with anti-VEGF-refractory mRCC. …”
Publicado 2014
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