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  1. 426521
    “…CONCLUSIONS: AMG 403 was generally safe and well-tolerated in both healthy volunteers and knee OA patients, and exhibited linear pharmacokinetics. …”
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    Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteoarthritis subjects
  2. 426522
    “…MRI’s performance was generally superior to ultrasound, mammography, and clinical examination, and it may be considered the most appropriate test in this setting. …”
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    Agreement between MRI and pathologic breast tumor size after neoadjuvant chemotherapy, and comparison with alternative tests: individual patient data meta-analysis
  3. 426523
    “…Bacillus Calmette-Guérin (BCG) is the most effective intravesical immunotherapy for superficial bladder cancer. Although generally well tolerated, BCG-related infectious complications may occur following instillation. …”
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    Bacillus Calmette-Guérin (BCG) Infection Following Intravesical BCG Administration as Adjunctive Therapy For Bladder Cancer: Incidence, Risk Factors, and Outcome in a Single-Institution Series and Review of the Literature
  4. 426524
    “…NAC-related side-effects were generally mild. NAC mainly benefited patients with stage III disease. …”
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    Neoadjuvant Chemotherapy Followed by Surgery Versus Surgery Alone for Colorectal Cancer: Meta-analysis of Randomized Controlled Trials
  5. 426525
    “…Life-space mobility (the University of Alabama at Birmingham Life-Space Assessment, LSA, range 0–120) was assessed at baseline and one and two years thereafter. Generalized estimating equations were used to analyze the effect of hearing difficulties on changes in LSA scores. …”
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    Self-reported hearing difficulties and changes in life-space mobility among community-dwelling older adults: a Two-year follow-Up study
  6. 426526
    “…Even if studies are generally restricted to a small subset of genes differentially expressed in specific diseases or experimental conditions, the number of potential correlations remains very high, and needs robust multivariate methods to be conveniently summarized by a small set of data. …”
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    Integrated ordination of miRNA and mRNA expression profiles
  7. 426527
    “…Using noninvasive scat deposition surveys for determination of kit fox presence, we modeled resource selection functions to predict kit fox distribution using three popular techniques (Maxent, fixed-effects, and mixed-effects generalized linear models) and compared these with similar models developed from invasive sampling (telemetry locations from radio-collared foxes). …”
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    Evaluation of Scat Deposition Transects versus Radio Telemetry for Developing a Species Distribution Model for a Rare Desert Carnivore, the Kit Fox
  8. 426528
    “…Statistical analysis was performed using linear and logistic regression through generalized estimating equation analysis so as to take into account repeated observation within subjects and adjust for session duration. …”
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    Effectiveness of Haemodiafiltration with Heat Sterilized High-Flux Polyphenylene HF Dialyzer in Reducing Free Light Chains in Patients with Myeloma Cast Nephropathy
  9. 426529
    “…Rate ratios and 95 % confidence intervals were estimated using generalized estimating equation Poisson regression models and were adjusted for race, sex, year of diagnosis, median household income, education, and population density. …”
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    Agricultural crop density and risk of childhood cancer in the midwestern United States: an ecologic study
  10. 426530
    “…The results were also consistent with auditory hair cells being generally more physiologically active when animals are in a reproductive state, a time of enhanced sensory-motor coupling between the auditory periphery and the upper harmonics of vocalizations. …”
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    Gene expression underlying enhanced, steroid-dependent auditory sensitivity of hair cell epithelium in a vocal fish
  11. 426531
    “…There was a relatively higher incidence of residual shunts and device migration in this series, generally due to the nonavailability of optimal device and surgical support. …”
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    Percutaneous closure of patent arterial ducts in patients from high altitude: a sub-Saharan experience
  12. 426532
    “…Their experiences indicate that CEM has helped to build pharmacovigilance capacity within the participating NCs and at the monitoring sites, and that healthcare providers (HCPs) are generally willing to participate in implementing the CEM method. …”
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    Experiences and Lessons From Implementing Cohort Event Monitoring Programmes for Antimalarials in Four African Countries: Results of a Questionnaire-Based Survey
  13. 426533
    por Chinomona, Amos, Mwambi, Henry
    Publicado 2015
    “…RESULTS: Across different subgroups of the population, the crude estimates of HIV prevalence are generally not identical but their variations are consistent between the two approaches (complete-case analysis and multiple imputation analysis). …”
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    Multiple imputation for non-response when estimating HIV prevalence using survey data
  14. 426534
    “…We found that all of the methods yielded results that are generally congruent. However, due to the increased numbers of categories, the CGST method provides much greater discriminatory power than the other methods tested here. …”
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    The Listeria monocytogenes Core-Genome Sequence Typer (LmCGST): a bioinformatic pipeline for molecular characterization with next-generation sequence data
  15. 426535
    “…BACKGROUND: Pilocytic astrocytoma is the most common type of brain tumor in the pediatric population, with a generally favorable prognosis, although recurrences or leptomeningeal dissemination are sometimes also observed. …”
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    Transcriptional profiles of pilocytic astrocytoma are related to their three different locations, but not to radiological tumor features
  16. 426536
    “…Analogous mutations in H(V)1 from the unicellular species Karlodinium veneficum and Emiliania huxleyi produced generally similar consequences. Saturation of ΔpH-dependent gating occurred at the same pH(o) and pH(i) in H(V)1 of all three species, suggesting that the same or similar group(s) is involved in pH sensing. …”
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    Tryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hH(V)1
  17. 426537
    “…Gene–gene interactions in case-control samples were identified by generalized multifactor dimensionality reduction (GMDR) method. …”
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    Interaction of Wnt pathway related variants with type 2 diabetes in a Chinese Han population
  18. 426538
    por Refai, Tamer Adel
    Publicado 2015
    “…INTRODUCTION: Apical protrusion in the central 4-mm ring in the Scheimflug imaging (Pentacam), both for the anterior and posterior floats as well as Corneal Hysteresis and Corneal Resistance Factor by Ocular Response Analyzer (ORA), generally are considered important predictors for post-Lasik ectasia. …”
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    Correlation between apical protrusion in the Scheimflug imaging and Corneal Hysteresis and Corneal Resistance factor by Ocular Response Analyzer, among refractive non-keratoconic Egyptian patients
  19. 426539
    “…Herein, 2,3-butanediol production was engineered in the Generally Regarded As Safe (GRAS) organism Corynebacterium glutamicum. …”
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    Engineering Corynebacterium glutamicum for the production of 2,3-butanediol
  20. 426540
    “…The mean lifelong learning score was 45.56. Rural physicians generally performed worse in the technical skills in seeking information domain. …”
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    Lifelong learning of Chinese rural physicians: preliminary psychometrics and influencing factors
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