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  1. 426641
    “…We used multivariable generalized estimating equations (GEE) to evaluate longitudinal changes in the proportion of participants with exposure to antiretroviral therapy (ART) in the previous 180 days, optimal adherence to ART (i.e. ≥95% vs. <95%) and non-detectable HIV-1 RNA viral load (VL <50 copies/mL plasma). …”
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    Improvements in HIV treatment outcomes among indigenous and non-indigenous people who use illicit drugs in a Canadian setting
  2. 426642
    “…These classifications were combined into patient-year smoking status and used to classify patients as ever versus never smokers and current smokers versus non-smokers. Generalized linear models were used to assess associations of HIV with 3 outcomes, ever smoking, current smoking, and current smoking in analyses limited to ever smokers (persistent smoking), while adjusting for demographics, cardiovascular risk factors, and psychiatric illness. …”
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    Determinants of Smoking and Quitting in HIV-Infected Individuals
  3. 426643
    “…BACKGROUND: Cluster headache (CH) is a debilitating condition that is generally associated with substantial health care costs. …”
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    Cost-effectiveness analysis of non-invasive vagus nerve stimulation for the treatment of chronic cluster headache
  4. 426644
    “…Usability perceptions were generally positive (3.67 for expert, mean of 3.33 for nonexperts). …”
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    Using Nonexperts for Annotating Pharmacokinetic Drug-Drug Interaction Mentions in Product Labeling: A Feasibility Study
  5. 426645
    “…Differential expression of sRNA candidates was explored in the wide type Mn with vs without sterol addition, and the steroid intermediate producing Mn strains vs wide type Mn with sterol addition, respectively. Generally, sRNA candidates were differentially expressed in various strains, but there were still some shared candidates with outstandingly upregulated or downregulated expression in these steroid producing strains. …”
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    RNA-Seq analysis uncovers non-coding small RNA system of Mycobacterium neoaurum in the metabolism of sterols to accumulate steroid intermediates
  6. 426646
    “…CONCLUSIONS: Iron estimation using the T2* CMR sequence in combination with Siemens’ in-line data processing is generally satisfactory and may help facilitate global access to tissue iron assessment. …”
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    Validation of T2* in-line analysis for tissue iron quantification at 1.5 T
  7. 426647
    “…BACKGROUND: The Gram-positive bacterium Bacillus subtilis has been widely used as a cell factory for the production of proteins due to its generally regarded as safe (GRAS) nature and secretion capability. …”
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    A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis
  8. 426648
    “…The strongest index hospitalization factors predictive of late COPD-related rehospitalization were use of steroids (any route: OR = 1.62 [P = 0.007]) and nebulizers (OR = 1.65 [P = 0.007]); neither predicted early COPD-related rehospitalization. Generally, factors predicting COPD-related rehospitalization were similar in both cohorts. …”
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    A retrospective analysis to identify predictors of COPD-related rehospitalization
  9. 426649
    “…FINDINGS: In June 2014, the monitoring system detected the expansion of a cluster by 11 new cases over three months, including eight cases with transmitted drug resistance. This cluster generally comprised young men who have sex with men. …”
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    Near real-time monitoring of HIV transmission hotspots from routine HIV genotyping: an implementation case study
  10. 426650
    “…RESULTS: HSAs had relatively strong interpersonal relationships with traditional leaders and volunteers, who were generally supportive of their work. From the health sector side, HSAs linked to health professionals and managers, but found them less supportive. …”
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    Health surveillance assistants as intermediates between the community and health sector in Malawi: exploring how relationships influence performance
  11. 426651
    “…The effects of extremely high temperatures generally persisted for 3 days, whereas the risk of extremely low temperatures could persist for 21 days. …”
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    The influence of temperature on mortality and its Lag effect: a study in four Chinese cities with different latitudes
  12. 426652
    “…Roughly 18% and 11% of TN1 and TN2 patients, respectively, experienced acute toxicities (all RTOG Grade 1 or 2), with the most common being sensory neuropathy, generalized pain, and nausea. Dmax > 75 Gy was not a predictor of toxicity incidence in TN1 cases (p = 0.597) but was significant for TN2 patients (p = 0.0009 following Fisher's exact test). …”
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    Stereotactic Radiosurgery for Trigeminal Neuralgia: A Retrospective Multi-Institutional Examination of Treatment Outcomes
  13. 426653
    “…Pearson correlations and t-tests were used to test for concurrent validity and differences between GPS-determined and self-reported transport in leisure time. Generalized linear models were used to determine the associations between the parental perceptions of the neighborhood environment and GPS-determined transport in leisure time. …”
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    Children’s GPS-determined versus self-reported transport in leisure time and associations with parental perceptions of the neighborhood environment
  14. 426654
    “…Costs were calculated from the societal perspective, including healthcare and social care costs, by multiplying each service unit with the relevant unit cost. Generalized linear models were used to investigate the relationship between total annual costs and various socio-demographic factors. …”
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    Economic burden of multimorbidity among older adults: impact on healthcare and societal costs
  15. 426655
    “…CONCLUSIONS: These results show long-term migration data can effectively predict the relative flows of infected people to direct malaria elimination policy, a particularly relevant result because migration data are generally easier to obtain than short-term movement data such as mobile phone records. …”
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    Census-derived migration data as a tool for informing malaria elimination policy
  16. 426656
    “…SCT400 serum half-life (T(1/2)), maximum concentration (C(max)) and area under the curve (AUC) generally increased between the first and fourth infusions (P<0.05). …”
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    Phase I study of chimeric anti-CD20 monoclonal antibody in Chinese patients with CD20-positive non-Hodgkin's lymphoma
  17. 426657
    “…CONCLUSIONS: Fluorophotometry generally did not correlate with any other DED tests, even though it showed capability of differentiating between DED and normal eyes up to 30 min after fluorescein dye instillation. …”
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    Corneal permeability changes in dry eye disease: an observational study
  18. 426658
    “…Attrition and patterns of missing values over time were evaluated using binomial generalized estimating equation (GEE) models and mean differences in key clinical outcomes were determined using normal GEE models. …”
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    Investigating the feasibility, acceptability and appropriateness of outreach case management in an urban Aboriginal and Torres Strait Islander primary health care service: a mixed methods exploratory study
  19. 426659
    “…Moreover, invertebrate filter-feeders are generally well adapted to the presence of refractory material in seston, which questions the potential of MPs at environmentally relevant concentrations to measurably affect digestion in these organisms. …”
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    The Effects of Natural and Anthropogenic Microparticles on Individual Fitness in Daphnia magna
  20. 426660
    “…Monthly applications of fipronil/(s)-methoprene (Frontline® Plus for Cats and Kittens, Merial) generally had high, but variable (68.2 to 99.9 %) efficacy over the course of the eight month study. …”
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    Evaluation and comparison of a flumethrin-imidacloprid collar and repeated monthly treatments of fipronil/(s)-methoprene to control flea, Ctenocephalides f. felis, infestations on cats for eight months
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