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  1. 426781
    “…Of 245 enrolled patients, 177 (72.2%) had local myalgia and 173 (70.6%) had local muscle tenderness. Generalized myalgia and muscle tenderness were present in 35 (14.2%) and 29 (11.8%) patients, respectively. …”
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    Clinical and Pharmacological Investigation of Myotoxicity in Sri Lankan Russell’s Viper (Daboia russelii) Envenoming
  2. 426782
    “…Children from private schools had generally lower HRQOL compared to those in public schools, but the associations with weight status were similar in both groups. …”
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    Relationship between weight status and health-related quality of life in Chinese primary school children in Guangzhou: a cross-sectional study
  3. 426783
    “…We employed filamentous growth as a tool to study the impact of pH on the hyphal growth regulator Cyr1, and we report that downregulation of cyclic AMP (cAMP) signaling by acidic pH contributes to the inhibition of hyphal growth in minimal medium with GlcNAc. Ras1 and Cyr1 are generally required for efficient hyphal growth, and the effects of low pH on Ras1 proteolysis and GTP binding are consistent with diminished cAMP output. …”
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    Global Role of Cyclic AMP Signaling in pH-Dependent Responses in Candida albicans
  4. 426784
    “…Yet, higher purine amounts were generally detected, on both sides, at 200 µL filling volume. …”
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    AB274. SPR-01 Mechanosensitive release of adenosine 5'-triphosphate and other purines from the bladder urothelium
  5. 426785
    “…Compared to CEE, E2 generally had more robust anxiolytic and antidepressant effects. …”
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    Benefits of Hormone Therapy Estrogens Depend on Estrogen Type: 17β-Estradiol and Conjugated Equine Estrogens Have Differential Effects on Cognitive, Anxiety-Like, and Depressive-Like Behaviors and Increase Tryptophan Hydroxylase-2 mRNA Levels in Dorsal Raphe Nucleus Subregions
  6. 426786
    “…The aim of the study was to evaluate the effect of standard-dose 0.625 mg conjugated equine estrogen (CEE) and half-dose 0.3 mg CEE daily with different progestogens in a continuous sequential regimen on postmenopausal metabolic parameters in generally healthy postmenopausal women. METHODS: A prospective, open-label, randomized controlled clinical trial was conducted between February 2014 and December 2015. …”
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    Effect of Half-dose and Standard-dose Conjugated Equine Estrogens Combined with Natural Progesterone or Dydrogesterone on Components of Metabolic Syndrome in Healthy Postmenopausal Women: A Randomized Controlled Trial
  7. 426787
    “…At the regional level, about 43.4%, 36.9%, 32.4% and 55.2% of residents in Ashanti, Central, Northern and Greater Accra region, respectively are overweight or obese. These patterns generally mimic the levels of urbanization. Per studies’ publication years, consistent increases in overweight and obesity prevalence were observed in Ghana in the period 1998–2016. …”
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    Overweight and obesity epidemic in Ghana—a systematic review and meta-analysis
  8. 426788
    “…Evidence for FI with minority ethnic groups generally, and African-Caribbeans in particular, is lacking. …”
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    Culturally-adapted Family Intervention (CaFI) for African-Caribbeans diagnosed with schizophrenia and their families: a feasibility study protocol of implementation and acceptability
  9. 426789
    “…Transformation specimens were generally composed of clones that were rare or absent in diagnostic specimens, consistent with dramatic clonal expansions that came to dominate the transformation specimens. …”
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    Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study
  10. 426790
    “…Two types of the model - based on linear and on generalized logistic function - were used to capture the data between the switch-points. …”
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    SwitchFinder – a novel method and query facility for discovering dynamic gene expression patterns
  11. 426791
    “…Contamination screening generally relies on reference-based methods such as database alignment or marker gene search, which limits the set of detectable contaminants to organisms with closely related reference species. …”
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    acdc – Automated Contamination Detection and Confidence estimation for single-cell genome data
  12. 426792
    “…RESULTS: Vaccine reactogenicity was mild, predictable and generally consistent with earlier Phase I studies with this vaccine. …”
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    An Intranasal Proteosome-Adjuvanted Trivalent Influenza Vaccine Is Safe, Immunogenic & Efficacious in the Human Viral Influenza Challenge Model. Serum IgG & Mucosal IgA Are Important Correlates of Protection against Illness Associated with Infection
  13. 426793
    “…On the non-lesional hemisphere, however, equally good plausibility rates (100%) were observed for both localizer techniques. fMRI-originated fibres generally followed a more posterior course relative to the nTMS-based tracts (p < 0.01) in both the lesional and non-lesional hemisphere. …”
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    Functional MRI vs. navigated TMS to optimize M1 seed volume delineation for DTI tractography. A prospective study in patients with brain tumours adjacent to the corticospinal tract
  14. 426794
    “…CONCLUSION: Due to the high and selective dropout rates, the results cannot be generalized and further research is necessary. Since the participation rate of the trainings was high, a need for further prevention programs is indicated. …”
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    Coping with stress in medical students: results of a randomized controlled trial using a mindfulness-based stress prevention training (MediMind) in Germany
  15. 426795
    “…According to the QHES, the quality of the studies was generally sufficient, but additional assessment revealed that most studies poorly represented the cost effectiveness of real-life medication use. …”
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    Systematic Review and Quality Appraisal of Cost-Effectiveness Analyses of Pharmacologic Maintenance Treatment for Chronic Obstructive Pulmonary Disease: Methodological Considerations and Recommendations
  16. 426796
    “…CONCLUSIONS: Resistance to a primary A. vasorum infection was generally higher in older animals, and this age resistance was reflected in lower worm counts and reduced excretion of larvae. …”
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    The effect of host age and inoculation dose on infection dynamics of Angiostrongylus vasorum in red foxes (Vulpes vulpes)
  17. 426797
    “…The change in systolic blood pressure, diastolic blood pressure, and fasting plasma glucose (FPG) over 18 months of intervention was quantified using generalized estimating equations models. During intervention, 6797 participants were enrolled. …”
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    Development of a Smartphone‐Enabled Hypertension and Diabetes Mellitus Management Package to Facilitate Evidence‐Based Care Delivery in Primary Healthcare Facilities in India: The mPower Heart Project
  18. 426798
    “…Relative decreases in all six predefined cardiovascular complications were generally more profound in adults with diabetes than in those without diabetes, which led to significant decrease in the relative risks of all six cardiovascular complications in subjects with diabetes over the past 8 years. …”
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    Improved trends in cardiovascular complications among subjects with type 2 diabetes in Korea: a nationwide study (2006–2013)
  19. 426799
    “…These represent adults who were aware of their conditions or visited a healthcare provider for the condition during the study period. Generalized linear models were used to estimate the marginal effects of CKD, cancer or stroke on adjusted expenditures compared to adults without CKD, cancer or stroke (n = 72,241) while controlling for demographics and co-morbidities and incorporating the sample weights of the complex survey design. …”
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    Non-dialysis dependent chronic kidney disease is associated with high total and out-of-pocket healthcare expenditures
  20. 426800
    “…Results of the studies included generally show statistically significant improvement on some, but not all, outcomes. …”
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    Evidence-based guideline implementation in low and middle income countries: lessons for mental health care
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