“…BACKGROUND: Patients with hemophilia and inhibitors generally face greater disease burden compared to patients without inhibitors. …”
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“…Prototype software performed semiautomatic segmentation to create RNFL en face images and quantified vessel area density (VAD), vessel skeleton density (VSD), and vessel complexity index (VCI) in the optic nerve head globally and focally. Generalized estimating equations models assessed association of OCTA parameters with VF mean deviation (MD) and RNFL thickness. …”
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“…However, RNA:DNA ratios decreased from 12 dph onward, indicating a generally low larval nutritional condition, probably leading to the point-of-no-return and subsequent irreversible mortality due to unsuccessful utilization of exogenous feeding. …”
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“…Treatment-related adverse events were more frequently observed in the Hepatectomy-TACE group, although these were generally mild and manageable. The most common grade 3 or 4 adverse events in both groups were neutropenia and liver dysfunction. …”
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“…HM formulas paratherapy were generally safe and well tolerated for PD patients (RR: 0.41, 95% CI: 0.21 to 0.80; P = 0.009). …”
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“…At similar instructed intensity and rating of perceived effort, women exhibited significantly higher relative heart rate (85±2% vs. 71±3% of maximum) and blood lactate levels (4.0±1.3 vs. 1.2±0.2 mmol/L) during LIT (all P < .001) than men, whereas physiological responses did generally not differ between the sexes during HIT. …”
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“…PURPOSE: Spirulina is generally used as a nutraceutical food supplement due to its nutrient profile, lack of toxicity, and therapeutic effects. …”
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“…CONCLUSIONS: Our study demonstrates that healthy volunteers are generally aware of and reflective about Phase I trial risks. …”
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“…In less developed countries, contraceptive discontinuation due to health concerns is generally higher, these complaints are often related to service quality. …”
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“…Counties tweeting more than expected were generally scattered throughout the study region with a small cluster at the base of Maine. …”
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“…For the 96-bp deletion-insertion single-nucleotide polymorphism (SNP) of the CYP2E1 gene, homozygous mutant-type significantly increased hepatotoxicity risk compared with homozygous wild-type (OR = 8.20, 95% CI 1.38–48.68, I(2) = 0%); no significant difference was observed for heterozygous genotype compared with homozygous wild-type (OR = 0.77, 95% CI 0.19–3.21, I(2) = 0%). CONCLUSIONS: Generally, we identified that coverage of the association between SNPs of CYP genes and anti-tuberculosis drug-related toxicity outcomes is incomplete. …”
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“…RESULTS: Respondents were generally against visiting MMP killer whale shows, with 60.9% not likely to visit. …”
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“…Structural lesions were infrequent and generally comparable in severity between TA–ER and TAcs but slightly higher in incidence for TA–ER. …”
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“…The cortical excitability pain measures were assessed before and 90 min after receiving the medication. Results: A generalized estimating equation (GEE) model revealed that in FM, pregabalin increased the CSP by 14.34% [confidence interval (CI) 95%; 4.02 to 21.63] and the placebo reduced the CSP by 1.58% (CI 95%; −57 to 25.9) (P = 0.00). …”
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“…Updated USCAST BKPTs, which were based on the application of population PK and PK-PD models, simulation techniques, and contemporary MIC distribution statistics, are generally lower than those of EUCAST/EMA, USA-FDA, and CLSI. …”
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“…It is unclear if these results generalize to female patients and other ethnic groups. …”
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“…Disease-, patient-, provider-, and hospital-factors associated with excess antibiotic duration and association of excess duration with patient outcomes were evaluated using multivariable generalized estimating equations models. RESULTS: A total of 3,776 patients were included in the final analysis (2,706 with CAP; 1,070 with HCAP). 69% (2,586/3,776) of patients received excess antibiotic duration (Figure 1). …”
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“…Diagnosis may be established by PCR and testing should be considered in culture-negative cases with associated risk factors. Outcome was generally favorable after a median antibiotic duration of 14 days. …”
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“…Patient and care data were extracted via the EMR. RESULTS: A generalized linear mixed effects model found an increase of 1.1 (95% CI 0.53–1.7) subglottic suction events per day (SS/day) on the day before VAE diagnosis, relative to the 4 prior days. …”
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“…RESULTS: Five hundred and eight HIV-infected detainees were identified; they were predominately male (88.4%), born in Mexico (37%), generally had CD4 counts >200 (86.2%) and had an established diagnosis of HIV prior to entering custody (94.1%). …”
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