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  1. 427961
    “…Some congruity exists in components between cultures, but generally they vary widely. The review gives an in-depth overview of mental health stigma reduction core components, providing researchers in varied resource-poor settings additional knowledge to help with planning mental health stigma reduction interventions.…”
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    Core components of mental health stigma reduction interventions in low- and middle-income countries: a systematic review
  2. 427962
    “…Treatment-emergent adverse events had similar incidence (52.8%–56.5%) across the treatment groups and were generally mild or moderate. Dizziness was the most frequent treatment-related treatment-emergent adverse events (AZL-M 80 mg, 1.9%; AZL-M 40 mg, 1.5%; valsartan, 1.0%). …”
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    A phase 3 double-blind randomized (CONSORT-compliant) study of azilsartan medoxomil compared to valsartan in Chinese patients with essential hypertension
  3. 427963
    “…CONCLUSIONS: Lacosamide was efficacious and generally safe as adjunctive treatment for uncontrolled PGTCS in patients with IGE.…”
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    Efficacy and safety of adjunctive lacosamide in the treatment of primary generalised tonic-clonic seizures: a double-blind, randomised, placebo-controlled trial
  4. 427964
    “…CONCLUSION: Overall, oral IMU-838 was generally well tolerated in SAD and MAD studies in healthy subjects over a wide dose range of 10–50 mg. …”
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    Safety, Tolerability and Pharmacokinetics of Vidofludimus calcium (IMU-838) After Single and Multiple Ascending Oral Doses in Healthy Male Subjects
  5. 427965
    “…CONCLUSIONS: Internet-based supportive interventions are generally effective at ameliorating depressive symptoms, perceived stress, anxiety, and self-efficacy in dementia caregivers and have potential benefits on care recipients. …”
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    Internet-Based Supportive Interventions for Family Caregivers of People With Dementia: Systematic Review and Meta-Analysis
  6. 427966
    “…IGF-I and GH levels were estimated with the ELISA method. Generalized estimating equations (GEE) model was applied for the first five assessments to analyze those longitudinal data. …”
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    Delirium, insulin-like growth factor I, growth hormone in older inpatients
  7. 427967
    “…In animals treated with the AQP4 inhibitor TGN-020, the perivascular Aβ40 accumulation was significantly (P < 0.001) intensified by involving four times more vessels, thus suggesting a generalized clearance defect associated with vessels. …”
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    Inhibition of Aquaporin 4 Decreases Amyloid Aβ40 Drainage Around Cerebral Vessels
  8. 427968
    “…We previously developed a generalized framework of circulatory equilibrium that consists of the integrated CO curve and the VR surface as common functions of right atrial pressure (P(RA)) and left atrial pressure (P(LA)). …”
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    The Partial Support of the Left Ventricular Assist Device Shifts the Systemic Cardiac Output Curve Upward in Proportion to the Effective Left Ventricular Ejection Fraction in Pressure-Volume Loop
  9. 427969
    “…Depression was examined using the 10-item Center for Epidemiological Studies–Depression scale score. Multiple generalized linear regression models, adjusting for self-reported sociodemographic characteristics, health behaviors, chronic conditions, and participants’ overall health, were used. …”
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    Association of Sensory Impairments With Cognitive Decline and Depression Among Older Adults in China
  10. 427970
    “…It is unknown whether this risk generalizes to non-elderly adults using newer antipsychotics as augmentation treatment for depression. …”
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    Mortality risk of antipsychotic augmentation for adult depression
  11. 427971
    “…Somatic-mutation signatures of tumors having a non-germline aberration in BRCA1/BRCA2 (n = 80) were generally similar to each other and to tumors from BRCA1/BRCA2 germline carriers (n = 44). …”
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    Effects of germline and somatic events in candidate BRCA-like genes on breast-tumor signatures
  12. 427972
    “…Research with sample sizes including more blacks with HCM and more precise measurement of symptoms is needed to generalize these results and examine potential contributing factors.…”
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    Blacks with Hypertrophic Cardiomyopathy Have Lower Quality of Life and Exercise Capacity Than Whites
  13. 427973
    “…BACKGROUND: Generally, oral immunotherapy (OIT) aims for daily administration. …”
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    Evaluation of oral immunotherapy efficacy and safety by maintenance dose dependency: A multicenter randomized study
  14. 427974
    “…Use of organic manures to meet the nutrient requirement of crop would be an inevitable practice in the years to come for sustainable agriculture since organic manures generally improve the soil physical, chemical and biological properties. …”
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    Different organic manure sources and NPK fertilizer on soil chemical properties, growth, yield and quality of okra
  15. 427975
    “…METHODS: Between January 10 and March 10, 2020, 290 frontline staff completed a questionnaire incorporating the Generalized Anxiety Disorder Scale 7 (GAD-7) to indicate their psychological behavior in the use of preventive medication. …”
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    Psychological Behavior of Frontline Medical Staff in the Use of Preventive Medication for COVID-19: A Cross-Sectional Study
  16. 427976
    “…RESULTS: Risk prediction equations generally fit well and exhibited good concordance, especially for the placebo arm. …”
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    Development and Internal Validation of a Discrete Event Simulation Model of Diabetic Kidney Disease Using CREDENCE Trial Data
  17. 427977
    “…Gene expression data was ordered by gene chromosomal coordinates as input to the 1D-CNN model, and the model utilizes multiple convolutional kernels with different configurations simultaneously to improve generality. The model was optimized through extensive hyperparameter tuning, including different max-pooling layers and dropout settings. …”
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    CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence
  18. 427978
    “…However, genus- and species-level dynamics are generally unknown, although important given that adaptation and acclimation processes differentiate at these levels. …”
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    Seasonal and Geographical Transitions in Eukaryotic Phytoplankton Community Structure in the Atlantic and Pacific Oceans
  19. 427979
    “…The prevalence of straight and kyphotic curvature had a significant increasing trend for both sexes and young generations, in which individuals 18 to 29 years of age generally had the highest prevalence rates during the study cycle (in 2018, kyphosis, 16.7%; 95% CI, 10.8%-22.5%; straight, 45.5%; 95% CI, 37.7%-53.3%). …”
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    Temporal Trends in Cervical Spine Curvature of South Korean Adults Assessed by Deep Learning System Segmentation, 2006-2018
  20. 427980
    “…Immunoinformatic and molecular modelling are time-efficient methods that are generally used to accelerate the discovery and design of the candidate peptides for vaccine development. …”
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    A Putative Prophylactic Solution for COVID-19: Development of Novel Multiepitope Vaccine Candidate against SARS-COV-2 by Comprehensive Immunoinformatic and Molecular Modelling Approach
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