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  1. 428341
    “…We also identified candidate loci (e.g., MTUS2, NOTCH4, EDAR, ADH1B, and ABCG2) with strong natural selection signatures in Guizhou Hans via iHS, nSL, and ihh, which were associated with the susceptibility of the multiple complex diseases, morphology formation, alcohol and lipid metabolism. Generally, we provided a case and ideal strategy to reconstruct the detailed demographic evolutionary history of Guizhou Hans, which provided new insights into the fine-scale genomic formation of one ethnolinguistically specific targeted population from the comprehensive perspectives of the shared unlinked alleles, linked haplotypes, and paternal and maternal lineages.…”
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    Fine-Scale Genetic Structure and Natural Selection Signatures of Southwestern Hans Inferred From Patterns of Genome-Wide Allele, Haplotype, and Haplogroup Lineages
  2. 428342
    “…After propensity score matching of baseline characteristics, for patients treated with insulin, the odds ratios of death from any cause in hospital, within 1 year of surgery, and within 2 years of surgery were 12.03 (95% CI: 1.486–97.33, P=0.020), 10.33 (95% CI: 1.21–88.12, P=0.033), and 2.99 (95% CI: 1.22–7.31, P=0.016), respectively, and the odds ratios of cardiac death were 10.33 (95% CI: 1.21-88.12, P=0.033), 6.49 (95% CI: 1.33–31.59, P=0.021), and 5.27 (95% CI: 1.45–19.13, P=0.011), respectively. Generalized estimating equations analysis showed the odds ratios of all-cause death and cardiac death for insulin-treated patients to be 4.77 (95% CI: 1.76–12.95, P=0.002) and 5.38 (95% CI: 1.29–22.96, P=0.023), respectively. …”
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    The effects of insulin therapy on mortality in diabetic patients undergoing percutaneous coronary intervention
  3. 428343
    “…BACKGROUND AND OBJECTIVES: Cognitive reserve (CR) is meant to account for the mismatch between brain damage and cognitive decline or dementia. Generally, CR has been operationalized using proxy variables indicating exposure to enriching activities (activity-based CR). …”
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    Cognitive Trajectories and Dementia Risk: A Comparison of Two Cognitive Reserve Measures
  4. 428344
    “…Carbon dioxide (CO(2)) is generally preferred as a supercritical solvent because of its lower temperature requirements, better diffusivity and easy removal. …”
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    Supercritical Carbon Dioxide Extracts of Cordyceps sinensis: Chromatography-based Metabolite Profiling and Protective Efficacy Against Hypobaric Hypoxia
  5. 428345
    “…Patients within 45 days of stroke onset were randomized to receive either four weeks of aerobic physical fitness training or relaxation sessions. Generalized estimating equation models were used to investigate the dynamics of inflammatory markers and the associations of exposure to fitness training with serum inflammatory markers over time. …”
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    Elevated Serum Inflammatory Markers in Subacute Stroke Are Associated With Clinical Outcome but Not Modified by Aerobic Fitness Training: Results of the Randomized Controlled PHYS-STROKE Trial
  6. 428346
    “…Participants completed the CIUS, the Pittsburgh Sleep Quality Index (PSQI) questionnaire, the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder Assessment-7 (GAD-7), and the WHO—Five Well-Being Index questionnaire (WHO-5). …”
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    Compulsive Internet Use Scale: Psychometric Properties and Associations With Sleeping Patterns, Mental Health, and Well-Being in Lithuanian Medical Students During the Coronavirus Disease 2019 Pandemic
  7. 428347
    “…Analyses were performed using three-level hierarchical generalized linear model. Level one was a 10% random sample of the eligible population in each département (n = 397,598). …”
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    Socio-Territorial Inequities in the French National Breast Cancer Screening Programme—A Cross-Sectional Multilevel Study
  8. 428348
    “…Although the capabilities of the platform are presented in the context of breast cancer research, they can be generalized to a variety of other tumor types that are characterized by high heterogeneity.…”
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    Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx(®) Digital Spatial Profiler
  9. 428349
    “…Compared to BBS7, we found that BBS1 patients generally had a milder ocular and systemic phenotype. …”
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    A Genotype–Phenotype Analysis of the Bardet–Biedl Syndrome in Puerto Rico
  10. 428350
    “…Among children, exposure to violence was associated with an increased risk of symptoms of generalized anxiety (β = 0.37, p = 0.006), major depressive (β = 0.24, p = 0.039), ADHD (β = 0.27, p = 0.040), PTSD (β = 0.52, p < 0.001), conduct (β = 0.58, p = 0.003) and oppositional defiant (β = 0.34, p = 0.032) disorders. …”
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    Associations Between Maternal Post-traumatic Stress Disorder and Traumatic Events With Child Psychopathology: Results From a Prospective Longitudinal Study
  11. 428351
    por Sanders, Julia, Blaylock, Rebecca
    Publicado 2021
    “…FINDINGS: Women were generally happy to adopt a precautionary approach and stringently social distance in the context of a relatively unknown pathogen and in an environment of extreme anxiety and uncertainty, but were acutely aware of the negative impacts. …”
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    “Anxious and traumatised”: Users’ experiences of maternity care in the UK during the COVID-19 pandemic
  12. 428352
    “…Influenza A(H3N2) virus was generally associated with higher morbidity and mortality, and was relatively more severe compared with influenza A(H1N1) and B viruses. …”
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    Development of influenza-associated disease burden pyramid in Shanghai, China, 2010–2017: a Bayesian modelling study
  13. 428353
    “…The highly expressed miRNAs were generally reported to be similar across lactational stage, milk fraction, maternal and infant characteristics, or infant growth and health. …”
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    Non-Coding RNAs in Human Breast Milk: A Systematic Review
  14. 428354
    por Fox, Ashley, Choi, Yongjin
    Publicado 2021
    “…Qualitatively examining reasons for hesitancy or confidence, we find that conspiracy beliefs do not figure prominently in people's vaccine hesitancy, but rather more quotidian (and legitimate) concerns about the speed of the development process and generalized lack of trust in the political and scientific institutions producing the vaccine contributing to a desire to “wait and see.” …”
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    Does Framing Coronavirus in Terms of Disparities Reduce or Increase Vaccine Hesitancy?
  15. 428355
    “…Moreover, the six most prevalent adverse effects were pain at the injection site (72.1%), generalized fatigue (40.5%), malaise (36.3%), myalgia (31,0%), headache (25.8%) and dizziness/weakness (21.6%). …”
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    Immune response (IgG) following full inoculation with BNT162b2 COVID-19 mRNA among healthcare professionals
  16. 428356
    “…To help assess potential neighborhood linked factors associated with the rates of web-based social services searches by individuals in need, we applied logistic regression using generalized estimating equation modeling. Baltimore City contained more disadvantaged neighborhoods compared to other areas in Maryland. …”
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    Internet Access, Social Risk Factors, and Web-Based Social Support Seeking Behavior: Assessing Correlates of the “Digital Divide” Across Neighborhoods in The State of Maryland
  17. 428357
    “…No significant changes in urinary albumin/creatinine ratio and blood pressure were observed. TRK‐100STP was generally well tolerated and most adverse drug reactions were mild or moderate in severity. …”
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    Prostacyclin analog beraprost sodium efficacy in primary glomerular disease or nephrosclerosis: Analysis of the Japanese subgroup in CASSIOPEIR study
  18. 428358
    “…Background: The existing prediction models lack the generalized applicability for chronic heart failure (CHF) readmission. …”
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    Development and Validation of a Nomogram to Predict the 180-Day Readmission Risk for Chronic Heart Failure: A Multicenter Prospective Study
  19. 428359
    “…This trend turned adverse after discharge and the values of quantitative features were generally higher in the smoking group than in the control group without statistical differences. …”
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    The Differences and Changes of Semi-Quantitative and Quantitative CT Features of Coronavirus Disease 2019 Pneumonia in Patients With or Without Smoking History
  20. 428360
    “…Multiple linear regression and generalized estimating equation (GEE) models were used to examine the associations of cord plasma concentrations of THs and TSH with AGI. …”
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    Association Between Neonatal Thyroid Function and Anogenital Distance from Birth to 48 Months of Age
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