“…Adjusted and Bonferroni-corrected generalized estimating equations modeled the associations of SCFA-producing gut microbes, fecal SCFA, and gut microbial diversity with glycemia and adiposity. …”
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“…Linear mixed effect models and logistic generalized estimating equations were used. RESULTS: 3,503 children who attended child care were included (mean age: 2.7 years at baseline). …”
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“…We aim to assess the effects of consuming a healthy US-style eating pattern, without or with unprocessed or processed lean red meats (LRM), on gut microbiota in generally healthy young adults. Secondary outcomes are fecal short-chain fatty acids (SCFAs) and cardiovascular risk factors. …”
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“…RESULTS: Compared with the healthy pregnant women, those who developed GDM tended to be older, have relatively higher pre-pregnancy BMI, more parities, higher triglycerides, and lower high-density lipoprotein-cholesterol. Generally, there was no significant association between intake of choline or betaine and risk of GDM [OR 0.77, 95% CI (0.41, 1.43) for choline; OR 0.80, 95% CI (0.42–1.52) for betaine] after adjustment for various covariates. …”
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“…Per age group, circulating levels of HS-CRP were associated with dietary Zn intake and either fasting status, energy intake and or carbohydrate intake while adjusting for WBC count, choline intake, folate intake, BMI, and gender. Survey weighted generalized linear models were constructed and the Rao-Scott likelihood ratio test was implemented via the survey package in R. …”
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“…The anthropometric, clinical, biochemical and dietary data of the participants were assessed periodically and their change from baseline were analysed using generalized linear model in SAS 9.4 version. RESULTS: The study was completed by 165 adults (response rate 82.5%). …”
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“…Though a dramatic change in 5-mC content is observed at the genome level, the variation in gene expression is generally less than that it is expected. Only less is understood about the significance of 5-mC in gene regulation under P-starvation stress in plants. …”
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“…The annual incidence between 2011 and 2017 {0.03 [95% confidence interval (CI): 0.01 to 0.11] to 0.05 (95% CI: 0.07 to 0.14) per million population} was generally lower than [0.07 (95% CI: 0.03 to 0.17) to 0.08 (95% CI: 0.03 to 0.18) per million] in 2018 and thereafter. …”
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“…However, to manage some lesions which locate between segment deep inside the parenchyma is still challenging. Generally, wedge resection and segmentectomy are optional for peripheral small lung cancer. …”
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“…We further conducted a generalized additive model (GAM) and a fitted smoothing curve with penalized spline method. …”
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“…To gain new insights into the mechanisms of poor tumor immunogenicity, we turned to pediatric cancers, which are generally unresponsive to checkpoint blockade. METHODS: RNA sequencing and clinical data were obtained for Wilms tumor, rhabdoid tumor, osteosarcoma, and neuroblastoma from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database, and adult cancers from The Cancer Genome Atlas (TCGA). …”
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“…Plasma markers of immune activation and microbial translocation (e.g., sCD14, sCD163, LPS-binding protein) were generally higher in PWH compared to HIV- CM, and these markers were positively associated with in vitro responsiveness to estrogen and LPS in CM with HIV. …”
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“…Next, we measured development (body weight), CNS regulation of metabolism, and other indicators of generalized, non-specific brain function as well as behaviors that are reliant on executive function, such as cognitive flexibility, impulse control, decision-making, and response inhibition. …”
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“…Individuals showed significantly higher agreement from pre-to-post on the self-efficacy item “I have a generally positive attitude toward writing” (p=0.047) using a 5-point Likert scale from “completely agree” to “completely disagree.” …”
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“…The systematic review revealed that several of the included studies did not use sufficient exercise intensity to elicit significant gastrointestinal disturbances or demonstrate any ergogenic benefit of CHO ingestion. Risk of bias was generally low across the included studies. CONCLUSIONS: This systematic review and meta-analysis demonstrate that the current literature indicates no benefit of adding sodium alginate to a CHO beverage during exercise. …”
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“…The frequency of local and systemic adverse events after the second dose was generally higher among healthy participants compared to patients with IBD. …”
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“…(pea) as a model crop. Generally, NaCl resulted in a progressive decrease in germinative attributes and physiological and biochemical parameters of P. sativum (L.). …”
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“…ABSTRACT: People who use drugs (PWUDs) are generally considered “hard-to-treat” patients, due to adherence to HCV antiviral therapy or re-infection concerns. …”
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“…Thirty patients were enrolled, with 26 evaluable for dose-limiting toxicity (DLT), with median age 12 years (3–20). Toxicities were generally mild; the most common grade 3/4 adverse events related to protocol therapy were neutropenia (18%), thrombocytopenia (11%), lymphopenia (11%), AST elevation (11%), and lipase elevation (11%). …”
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“…SIMPLE SUMMARY: Leptomeningeal metastasis (LM) is a devastating complication of lung cancer, with a generally poor outcome. We conduct the present study to evaluate the association between clinical presentations, brain images, tumor cell counts of the cerebrospinal fluid (CSF), and the epidermal growth factor receptor (EGFR) mutation detection rate in CSF among EGFR-mutant lung adenocarcinoma patients with LM and accessed the influence of the timing of LM occurrence on patient outcomes. …”
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