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  1. 429701
    “…BACKGROUND: Bacillus amyloliquefaciens is generally recognized as food safe (GRAS) microbial host and important enzyme-producing strain in the industry. …”
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    Development and application of a fast and efficient CRISPR-based genetic toolkit in Bacillus amyloliquefaciens LB1ba02
  2. 429702
    “…CONCLUSIONS: In summary, a "high-efficiency, low-carbon, cofactor-recycling" MK-7 synthetic strain was constructed, and the strategy used in this study can be generally applied for constructing high-efficiency synthesis platforms for other terpenoids, laying the foundation for the large-scale production of high-value MK-7 as well as terpenoids. …”
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    Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis
  3. 429703
    “…Birth attendants were generally satisfied with the assembly of the kit. Many women cited unawareness and cost to be a major impediment in use of CDKs.…”
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    Effect of a community based social marketing strategy on the uptake of clean delivery kits in peri-urban communities of Karachi, Pakistan
  4. 429704
    “…CONCLUSION: Limited evidence suggests that SMBP during pregnancy is feasible and acceptable, and generally associated with maternal and neonatal health outcomes similar to clinic-based monitoring. …”
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    Self-monitoring of blood pressure among women with hypertensive disorders of pregnancy: a systematic review
  5. 429705
    “…The survey (n=111) indicated that service providers generally regarded their organisational implementation climate as supportive in implementing iCBT services. …”
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    Organisational implementation climate in implementing internet-based cognitive behaviour therapy for depression
  6. 429706
    “…The hypotheses will be tested using generalized mixed models with covariates guided by the Andersen Behavioral Model of Health Services. …”
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    Improving transitions and outcomes of sepsis survivors (I-TRANSFER): a type 1 hybrid protocol
  7. 429707
    por Burkova, Valentina N., Butovskaya, Marina L., Randall, Ashley K., Fedenok, Julija N., Ahmadi, Khodabakhsh, Alghraibeh, Ahmad M., Allami, Fathil Bakir Mutsher, Alpaslan, Fadime Suata, Al-Zu’bi, Mohammad Ahmad Abdelaziz, Al-Mseidin, Kholoud Imhammad Meqbel, Biçer, Derya Fatma, Cetinkaya, Hakan, David, Oana Alexandra, Donato, Silvia, Dural, Seda, Erickson, Paige, Ermakov, Alexey M., Ertuğrul, Berna, Fayankinnu, Emmanuel Abiodun, Fisher, Maryanne L., Al Gharaibeh, Fakir, Hocker, Lauren, Hromatko, Ivana, Kasparova, Elena, Kavina, Alexander, Khatatbeh, Yahya M., Khun-Inkeeree, Hareesol, Kline, Kai M., Koç, Fırat, Kolodkin, Vladimir, MacEacheron, Melanie, Maruf, Irma Rachmawati, Meskó, Norbert, Mkrtchyan, Ruzan, Nurisnaeny, Poppy Setiawati, Ojedokun, Oluyinka, Adebayo, Damilola, Omar-Fauzee, Mohd S. B., Özener, Barıs, Ponciano, Edna Lúcia Tinoco, Rizwan, Muhammad, Sabiniewicz, Agnieszka, Spodina, Victoriya I., Stoyanova, Stanislava, Tripathi, Nachiketa, Upadhyay, Satwik, Weisfeld, Carol, Yaakob, Mohd Faiz Mohd, Yusof, Mat Rahimi, Zinurova, Raushaniia I.
    Publicado 2022
    “…Level of anxiety was measured by means of the 7-item Generalized Anxiety Disorder Scale (GAD-7) and the 20-item first part of The State-Trait Anxiety Inventory (STAI)—State Anxiety Inventory (SAI). …”
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    Factors Associated With Highest Symptoms of Anxiety During COVID-19: Cross-Cultural Study of 23 Countries
  8. 429708
    “…Survival estimates demonstrated no differences, generally showing short median PFS (BCOR-fusion, 2 years, n=15; BCOR-ITD, 1.8 years, n=55) and intermediate OS rates (BCOR-fusion, 6.8 years, n=18; BCOR-ITD 6.3 years, n=60). …”
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    ETMR-06. Molecular and clinical characteristics of CNS tumors withBCOR(L1) fusion/internal tandem duplication
  9. 429709
    “…Recently, P. pastoris has also been exploited as an attractive cell factory for the production of high-value biochemicals due to Generally Recognized as Safe (GRAS) status and high growth rate of this yeast strain. …”
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    Metabolic engineering of Pichia pastoris for myo-inositol production by dynamic regulation of central metabolism
  10. 429710
    “…Aiming for malaria prevalence reduction, we identify and quantify key determinants of intervention impact along with their minimal properties required to achieve the desired health goals. While coverage is generally identified as the largest driver of impact, higher efficacy, longer protection duration or multiple deployments per year are needed to increase prevalence reduction. …”
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    Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions
  11. 429711
    “…Severity of most ocular signs and symptoms was significantly reduced during the study period, and PF tafluprost/timolol FC was generally well tolerated.…”
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    Treatment of Open-Angle Glaucoma and Ocular Hypertension with the Fixed-Dose Combination of Preservative-Free Tafluprost/Timolol: Clinical Outcomes from Ophthalmology Clinics in Italy
  12. 429712
    “…Outbreak status may reflect a generally susceptible population, due to overlapping factors, including climate, policy, and individual behavior. …”
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    Online Artículo Texto
    Overlapping Delta and Omicron Outbreaks During the COVID-19 Pandemic: Dynamic Panel Data Estimates
  13. 429713
    “…The c-index showed broadly similar discrimination between all modelling approaches. Models were generally well calibrated, but random survival forest underfitted the predicted risk of TKA revision compared to regression approaches. …”
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    A comparison of survival models for prediction of eight-year revision risk following total knee and hip arthroplasty
  14. 429714
    “…Less experienced reviewers were generally more positive, and they saw more benefits and were able to use the tool more flexibly. …”
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    Online Artículo Texto
    Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system
  15. 429715
    “…The small number of studies was possibly due to a generally low research uptake in radiography. The main outcome for four studies was reduced length of stay in ED, with recall and re-attendance to ED a primary outcome in one study and secondary outcome for two other studies. …”
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    Radiographer-led discharge for emergency care patients, requiring projection radiography of minor musculoskeletal injuries: a scoping review
  16. 429716
    “…Correlations of the AR-PAID-5 with the Arabic versions of the 20-item Problem Areas in Diabetes (PAID), Patient Health Questionnaire 9 (PHQ-9), Generalized Anxiety Disorder 7 (GAD-7), 5-item World Health Organization Well-Being Index (WHO-5) scales and glycated hemoglobin (HbA1c) were investigated for supporting the convergent validity. …”
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    Psychometric evaluation of the Arabic version of the 5-item Problem Areas in Diabetes (AR-PAID-5) scale
  17. 429717
    “…Nuclear sclerosis severity [β = 8.99 (95% CI 3.35, 14.6), p = 0.00177] was associated with post-operative change in BCVA and central foveal ellipsoid zone (EZ) breaks [OR 1.33 × 10(–9) (95% CI 5.12 × 10(–10)–3.43 × 10(−9)), p < 0.001] on OCT was inversely correlated with post-operative BCVA > 20/40 using a multivariate generalized linear model. Central foveal EZ breaks [HR 1.77 × 10(9) (95% CI 3.86 × 10(8), 8.11 × 10(9)), p < 0.001] and MacTel Type 2 disease stage [HR 2.83, (95% CI 1.12, 7.12), p = 0.027] were independently associated with shorter time to vision loss of two lines or more in a multivariate Cox regression model. …”
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    Visual acuity after cataract surgery in Macular Telangiectasia Type 2 Stage 3 to 5
  18. 429718
    “…Blood meals and species identification of blood-fed specimens were determined using cytochrome c oxidase I subunit (COI) DNA barcoding. Multivariate generalized linear models were used to evaluate the associations between the abundance of Culicoides, the species richness and other parameters. …”
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    Culicoides species community composition and feeding preferences in two aquatic ecosystems in northern Spain
  19. 429719
    “…Of those who spoke with their PCP about medical cannabis (82.2%, n = 2217), 38.6% (n = 857) reported that their PCP had “very good” or “excellent” knowledge of medical cannabis and, on average, were moderately confident in their PCP’s ability to integrate medical cannabis into treatment. Participants generally reported higher ratings for secondary care providers, with 82.8% (n = 808) of participants rating their secondary care provider’s knowledge about medical cannabis as “very good” or “excellent.” …”
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    Healthcare provider and medical cannabis patient communication regarding referral and medication substitution: the Canadian context
  20. 429720
    “…The functional regions supporting the diagnosis decision were generally consistent with known parkinsonian pathology but provided more specific guidance for feature selection and quantitative analysis. …”
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    Decoding the dopamine transporter imaging for the differential diagnosis of parkinsonism using deep learning
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