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  1. 431381
    “…BACKGROUND: Immune checkpoint inhibitors (ICIs), an enormous oncological breakthrough in the last 10 years, have become the standard treatments for several types of solid cancers. Although ICIs are generally well tolerated and result in favorable outcomes, they also cause unique immune-related adverse events (irAEs) across bodily systems and organs. …”
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    Immune thrombocytopenia in a small cell lung cancer patient treated with atezolizumab: a case report
  2. 431382
    “…Guideline adherence was defined as: 1) ≥ 30 min/day of tummy time, 2) no screen time, some reading time, no restrained bouts > 1 h (time-use diary only), and 3) 14–17 h (2 months) or 12–16 h (4 and 6 months) of sleep per 24-h period. Generalized estimating equations were conducted as well as linear mixed models and linear regression models that adjusted for demographic characteristics. …”
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    Adherence to Canadian 24-Hour Movement Guidelines among infants and associations with development: a longitudinal study
  3. 431383
    “…However, actors in the farming systems and the enabling environment generally focused on the immediate issues and gave little real consideration to long-term implications and challenges. …”
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    Impact of Covid-19 on farming systems in Europe through the lens of resilience thinking
  4. 431384
    “…Between group differences including intervention effect after the 3 month long intervention and after 6 months of follow-up, were assessed using generalized estimating equation models. RESULTS: In total, 166 participants, 108 men and 58 women, with complete baseline data on RAND-36 were included in analysis. …”
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    The effect of the smartphone app DiaCert on health related quality of life in patients with type 2 diabetes: results from a randomized controlled trial
  5. 431385
    “…Overall, evobrutinib treatment (all doses) was generally well tolerated across indications. TRIAL REGISTRATION NUMBERS: NCT02975349, NCT03233230, NCT02975336.…”
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    Characterisation of the safety profile of evobrutinib in over 1000 patients from phase II clinical trials in multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus: an integrated safety analysis
  6. 431386
    “…RESULTS: Among 75 159 CAS+IMD-treated and 1 670 338 EUA-eligible untreated patients, 73 759 treated patients were matched to 310 688 untreated patients; matched patients were ~50 years, ~60% were women and generally well balanced across risk factors. The 30-day risk of the composite outcome was 2.1% and 5.2% in the CAS+IMD-treated and CAS+IMD-untreated patients, respectively; equivalent to a 60% lower risk (aHR 0.40; 95% CI, 0.38 to 0.42). …”
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    Real-world effectiveness of casirivimab and imdevimab among patients diagnosed with COVID-19 in the ambulatory setting: a retrospective cohort study using a large claims database
  7. 431387
    “…Joinpoint regression and survey-weighted generalized linear models were used to analyze trends and influence factors, respectively. …”
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    Trends and influence factors in the prevalence, intervention, and control of metabolic syndrome among US adults, 1999–2018
  8. 431388
    “…Association of the AL elongation, ibARAL and ibRRAL with age, sex and ocular parameters was analyzed by correlation analysis and generalized estimating equation (GEE) analysis. RESULT: The average initial wearing age was 10.76 ± 1.45 (ranged 8.5 to 15.8). …”
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    Assessing the efficacy of myopia control in monocular orthokeratology treated unilateral myopic children
  9. 431389
    “…A binary logistic regression model was then used to assess the independent relationship between RC level and DR and proliferative diabetic retinopathy (PDR). A generalized additive model (GAM) and smooth curve fitting were used to investigate the actual shape of the curve between them. …”
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    The non-linear link between remnant cholesterol and diabetic retinopathy: a cross-sectional study in patients with type 2 diabetic mellitus
  10. 431390
    “…WHAT IS ALREADY KNOWN AND THE RESIDUAL QUERY: Corneal refractive surgery generally demonstrates significant postoperative Goldmann IOP reductions. …”
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    Goldmann and modified Goldmann tonometry measuring intraocular pressure changes in eyes which underwent myopic laser in situ Keratomileusis and photorefractive keratectomy
  11. 431391
    “…No significant difference was found between the chronological age and dental age using the London Atlas, generally for the 10 to 15 years group (p > 0.05), but our quick method for the 15–16 years children (p < 0.05) and Willems method (p < 0.001). …”
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    Performance of the London Atlas, Willems, and a new quick method for dental age estimation in Chinese Uyghur children
  12. 431392
    “…After the outbreak of COVID-19 pandemic, the total antibiotic consumption decreased generally and the use pattern was improved to some extent in the PHSs in Shandong, China. …”
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    Antibiotic use in township hospitals during the COVID-19 pandemic in Shandong, China
  13. 431393
    “…Data were abstracted from FP registers for a 15-month period from October 1, 2017 until December 31, 2018 to understand cervical cancer screening prevalence. Generalized linear models were used to calculate prevalence ratios (PR) and identify clinic-level correlates of reporting any cervical cancer screening. …”
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    A cross-sectional study of the prevalence, barriers, and facilitators of cervical cancer screening in family planning clinics in Mombasa County, Kenya
  14. 431394
    por Alahmad, Barrak, Khraishah, Haitham, Royé, Dominic, Vicedo-Cabrera, Ana Maria, Guo, Yuming, Papatheodorou, Stefania I., Achilleos, Souzana, Acquaotta, Fiorella, Armstrong, Ben, Bell, Michelle L., Pan, Shih-Chun, de Sousa Zanotti Stagliorio Coelho, Micheline, Colistro, Valentina, Dang, Tran Ngoc, Van Dung, Do, De’ Donato, Francesca K., Entezari, Alireza, Guo, Yue-Liang Leon, Hashizume, Masahiro, Honda, Yasushi, Indermitte, Ene, Íñiguez, Carmen, Jaakkola, Jouni J.K., Kim, Ho, Lavigne, Eric, Lee, Whanhee, Li, Shanshan, Madureira, Joana, Mayvaneh, Fatemeh, Orru, Hans, Overcenco, Ala, Ragettli, Martina S., Ryti, Niilo R.I., Saldiva, Paulo Hilario Nascimento, Scovronick, Noah, Seposo, Xerxes, Sera, Francesco, Silva, Susana Pereira, Stafoggia, Massimo, Tobias, Aurelio, Garshick, Eric, Bernstein, Aaron S., Zanobetti, Antonella, Schwartz, Joel, Gasparrini, Antonio, Koutrakis, Petros
    Publicado 2022
    “…Existing studies on the association between temperatures and cardiovascular deaths have been limited in geographic zones and have generally considered associations with total cardiovascular deaths rather than cause-specific cardiovascular deaths. …”
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    Associations Between Extreme Temperatures and Cardiovascular Cause-Specific Mortality: Results From 27 Countries
  15. 431395
    por Yu, Xiaowei, Zhang, XiaoYuan, Wang, Qun
    Publicado 2022
    “…Validated assessment tools for erectile dysfunction (the International Index of Erectile Function -IIEF-5) and anxiety (the seven-item Generalized Anxiety Disorder Scale- GAD-7) were also used. …”
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    Sexual dysfunction is more common among men who have high sperm DNA fragmentation or teratozoopermia
  16. 431396
    “…These individuals requesting tests for travel generally had no clinical symptoms of COVID-19 at the time of testing. …”
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    SARS-CoV-2 infections among asymptomatic individuals contributed to COVID-19 cases: A cross-sectional study among prospective air travelers from Ghana
  17. 431397
    “…Analyses will primarily use generalized linear mixed modeling (GLMM) to evaluate the relationships between predictors and outcomes. …”
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    The mastery lifestyle intervention to reduce biopsychosocial risks for pregnant Latinas and African Americans and their infants: protocol for a randomized controlled trial
  18. 431398
    “…CONCLUSIONS: This study shows that the adapted scale structure of the EORTC-QLQ-BLM30 generally exhibits good measurement properties in Dutch patients, but needs to be validated in other languages and settings. …”
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    Validation and reliability of the Dutch version of the EORTC QLQ-BLM30 module for assessing the health-related quality of life of patients with muscle invasive bladder cancer
  19. 431399
    “…PBL experiences were generally highly rated, but favorable student experiences were not reliable indicators of better academic or behavioral outcomes. …”
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    Does your group matter? How group function impacts educational outcomes in problem-based learning: a scoping review
  20. 431400
    “…The Prime MM-GBSA (molecular mechanics/generalized Born surface area) method was used as a validation tool after the docking stage and for the averaged clusters after the MD simulation stage. …”
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    Studies of the symmetric binding mode of daclatasvir and analogs using a new homology model of HCV NS5A GT-4a
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