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  1. 431461
    “…Additionally, mNGS can detect pathogens that are not generally covered by CT, which is extremely important for the modification of the treatment strategy.…”
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  2. 431462
    “…Despite its focus on the use case of Greece, the proposed approach can be generalized to other locations, populations, and social media platforms to support the surveillance of infectious diseases with the ultimate goal of reinforcing preparedness for future epidemics.…”
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  3. 431463
  4. 431464
    “…CONCLUSIONS: In participants from Asia with T2D inadequately controlled by metformin monotherapy, and BMI ≥24 kg/m(2), ertugliflozin (5 mg or 15 mg) resulted in greater glycemic and body weight reductions compared with placebo and was generally well tolerated. TRIAL REGISTRATION: Clinicaltrials.gov identifiers NCT02033889, NCT02630706. …”
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  5. 431465
    “…Pregnancy was described as a critical motivator for men’s HIVST uptake, while HIV status of pregnant women was influential in couples’ communal coping and health-enhancing behaviours. Generally, participants felt HIV-negative women would be more likely to deliver HIVST, while women with HIV would be more hesitant due to concerns about discovery of serodifference and relationship dissolution. …”
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  6. 431466
    “…Other non-motor clinical measures emerged as key predictors, while participant demographics predictors (with the exception of age) were generally less important across the models. Models built with the bagging algorithms outperformed the single decision tree for in-sample accuracy (26–30% better classification) but had only modest cross-validation accuracy (48–55% out of bag classification). …”
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  7. 431467
    “…Given the increasing availability of evidence-based health-apps designed for older populations, this may result in entirely avoidable unmet needs, suggesting that more should be done by healthcare professionals to recommend health-apps to older persons who are generally positive about their use. This may result in considerable improvements in healthy and independent ageing.…”
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  8. 431468
    “…CONCLUSIONS: TDMH was homogenous and exhibited significant stability and almost completely recovered after excessive compression. TDMH generally maintained their bulk geometry throughout 7 weeks. …”
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  9. 431469
    “…CONCLUSIONS: The “spontaneous” or posttraumatic rupture of SACs is a rare but potentially significant complication followed by a generally good outcome. The course of the cyst is independent from the outcome of the complication, consequently requiring specific investigations for individuating those lesions interfering with CSF dynamics and/or cerebral blood flow.…”
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  10. 431470
    “…BACKGROUND: In contrast to protein-rich insect meal, the feed potential of insect fat is generally less explored and knowledge about the suitability of insect fat as a fat source specifically in broiler diets is still limited. …”
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  11. 431471
    “…Implementation data highlighted challenges with intervention uptake and attendance. Outcome measures generally had strong psychometric properties (range: α = 0.77 to α = 87), however did not demonstrate change over time in either group. …”
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  12. 431472
    “…Although a strict classification of microglia remains elusive given their capacity to adapt to the environment and their morphological, ultrastructural and molecular dynamism, diabetes modulates microglial phenotypic states, triggering specific responses that include upregulation of activity markers (such as Iba1, CD11b, CD68, MHC-II and F4/80), morphological shift to amoeboid shape, secretion of a wide variety of cytokines and chemokines, metabolic reprogramming and generalized increase of oxidative stress. Pathways commonly activated by diabetes-related conditions include NF-κB, NLRP3 inflammasome, fractalkine/CX3CR1, MAPKs, AGEs/RAGE and Akt/mTOR. …”
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  13. 431473
    “…However, while Spearman’s coefficients (r(s)) ranged between 0.478 and 0.681, R(2) values were generally low. In contrast, an excellent correlation of myocardial (18)F-flurpiridaz uptake with V(T) was obtained, particularly when employing the averaged myocardial uptake from 20 to 40 min post tracer injection (R(2) ≥ 0.98). …”
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  14. 431474
    “…RESULTS: The feasibility of the intervention was established with a high attendance rate (87.5%), high usability score (79), and low attrition rate (1.6%). The generalized estimating equation results showed that participants in the intervention group at T1 and T2 experienced a significant improvement in stress reduction (P=.02 and P=.04, respectively), sleep quality (P=.004 and P=.01, respectively), and mindful awareness and attention (P=.006 and P=.02, respectively) compared with the control group. …”
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  15. 431475
    “…Five physical function outcomes were assessed: handgrip strength (dynamometer), balance ability (single leg stance), gait speed (11-m walking), basic functional mobility (time up and go), and lower-limb strength (five times sit-to-stand). Generalized linear models were used to examine the associations of the overall and time-specific breaks in sedentary time with the physical function outcomes. …”
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  16. 431476
    “…RESULTS: Based on 40 studies with 12,424 individuals, the pooled prevalence of any long COVID was 23.36 % ([95 % CI 15.27–32.53]). The generalized symptom (19.57 %, [95 % CI 9.85–31.52]) was reported most commonly, followed by respiratory (14.76 %, [95 % CI 7.22–24.27]), neurologic (13.51 %, [95 % CI 6.52–22.40]), and psychiatric (12.30 %, [95% CI 5.38–21.37]). …”
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  17. 431477
    por Gafar, Fajri, Wasmann, Roeland E., McIlleron, Helen M., Aarnoutse, Rob E., Schaaf, H. Simon, Marais, Ben J., Agarwal, Dipti, Antwi, Sampson, Bang, Nguyen D., Bekker, Adrie, Bell, David J., Chabala, Chishala, Choo, Louise, Davies, Geraint R., Day, Jeremy N., Dayal, Rajeshwar, Denti, Paolo, Donald, Peter R., Engidawork, Ephrem, Garcia-Prats, Anthony J., Gibb, Diana, Graham, Stephen M., Hesseling, Anneke C., Heysell, Scott K., Idris, Misgana I., Kabra, Sushil K., Kinikar, Aarti, Kumar, Agibothu K. Hemanth, Kwara, Awewura, Lodha, Rakesh, Magis-Escurra, Cecile, Martinez, Nilza, Mathew, Binu S., Mave, Vidya, Mduma, Estomih, Mlotha-Mitole, Rachel, Mpagama, Stellah G., Mukherjee, Aparna, Nataprawira, Heda M., Peloquin, Charles A., Pouplin, Thomas, Ramachandran, Geetha, Ranjalkar, Jaya, Roy, Vandana, Ruslami, Rovina, Shah, Ira, Singh, Yatish, Sturkenboom, Marieke G.G., Svensson, Elin M., Swaminathan, Soumya, Thatte, Urmila, Thee, Stephanie, Thomas, Tania A., Tikiso, Tjokosela, Touw, Daan J., Turkova, Anna, Velpandian, Thirumurthy, Verhagen, Lilly M., Winckler, Jana L., Yang, Hongmei, Yunivita, Vycke, Taxis, Katja, Stevens, Jasper, Alffenaar, Jan-Willem C.
    Publicado 2023
    “…Determinants of C(max) were generally similar to those for AUC(0–24). CONCLUSIONS: This study provides the most comprehensive estimates of plasma exposures to first-line anti-TB drugs in children and adolescents. …”
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  18. 431478
    por Liu, Yueyue, Wan, Chuchuan, Xi, Xiaoyu
    Publicado 2023
    “…The results of subgroup analysis were generally consistent with those of the full sample. …”
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  19. 431479
    por Oliveira, Gonçalo
    Publicado 2014
    “…The magnetic susceptibility above T$_{N}$ (21 K) has shown a peculiar behavior, generally attributed to the development of 2D short-range magnetic correlations due to strong frustration coming from antiferromagnetic exchange interactions in a triangular lattice. …”
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  20. 431480
    por Zhang, Gang
    Publicado 2021
    “…Such final state can be used to search for new particles in the low-mass range generally. The data used in this analysis was LHC proton–proton collisions collected by the ATLAS experiment at a centre-of-mass energy of 13 TeV from 2015 to 2017, corresponding to an integrated luminosity up to $79.8\ \text{fb}^{-1}$. …”
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