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431781por Mantegna, Giovanna, Petrillo, Marco, Fuoco, Gilda, Venditti, Laura, Terzano, Serena, Anchora, Luigi Pedone, Scambia, Giovanni, Ferrandina, Gabriella“…METHODS: The questionnaires: Hospital Anxiety and Depression Scale (HADS), Global Health Status items of EORTC QLQ-C30 (GHS), and EORTC QLQ-CX24 (CX24) have been administered by a dedicated team of psycho-oncologists, administered at baseline, and after 3, 6, 12 and 24 months from surgery The Generalized Linear Model for repeated measure was used to analyze modifications of QoL measures over time. …”
Publicado 2013
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431782“…Conclusively, all the photosynthetic parameters that were examined in this study were generally higher in the HTI-resistant ginseng lines than in the HTI-susceptible lines, except for HTIR 2, and were much higher in August than in July, especially in the resistant ginseng lines. …”
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431783“…When the conditions were compared at week 4, the differences between the conditions were generally similar to the findings observed at week 0. …”
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431784“…Outbreak detection methods generally attempt to identify anomalies in time, but do not identify the type or source of an outbreak. …”
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431785“…The standardization of definitions used for detection will allow for generalization across institutions. [Table: see text]…”
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431786por Hou, Jian, Du, Xin, Jin, Jie, Cai, Zhen, Chen, Fangping, Zhou, Dao-bin, Yu, Li, Ke, Xiaoyan, Li, Xiao, Wu, Depei, Meng, Fanyi, Ai, Huisheng, Zhang, Jingshan, Wortman-Vayn, Honeylet, Chen, Nianhang, Mei, Jay, Wang, Jianmin“…Lenalidomide plus low-dose dexamethasone is effective and generally well tolerated in Caucasian RRMM patients, but no previous study has evaluated this regimen in Chinese RRMM patients. …”
Publicado 2013
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431787por Kemp, John P., Smith, Paul M., Pyle, Angela, Neeve, Vivienne C. M., Tuppen, Helen A. L., Schara, Ulrike, Talim, Beril, Topaloglu, Haluk, Holinski-Feder, Elke, Abicht, Angela, Czermin, Birgit, Lochmüller, Hanns, McFarland, Robert, Chinnery, Patrick F., Chrzanowska-Lightowlers, Zofia M.A., Lightowlers, Robert N., Taylor, Robert W., Horvath, Rita“…Mutations in several mitochondrial DNA and nuclear genes involved in mitochondrial protein synthesis have recently been reported in combined respiratory chain deficiency, indicating a generalized defect in mitochondrial translation. However, the number of patients with pathogenic mutations is small, implying that nuclear defects of mitochondrial translation are either underdiagnosed or intrauterine lethal. …”
Publicado 2011
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431788por Bredholt, Therese, Ersvær, Elisabeth, Erikstein, Bjarte Skoe, Sulen, André, Reikvam, Håkon, Aarstad, Hans Jørgen, Johannessen, Anne Christine, Vintermyr, Olav Karsten, Bruserud, Øystein, Gjertsen, Bjørn Tore“…RESULTS: Cathinone, cathine and norephedrine generally reduced post-translational modifications of intracellular signal transducers in T-lymphocytes, B-lymphocytes, natural killer cells and monocytes, most prominently affecting c-Cbl (pTyr700), ERK1/2 (p-Thr202/p-Tyr204), p38 MAPK (p-Thr180/p-Tyr182) and p53 (both total p53 protein and p-Ser15). …”
Publicado 2013
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431789por Hong, Keun-Sik, Bang, Oh Young, Kim, Jong S., Heo, Ji Hoe, Yu, Kyung-Ho, Bae, Hee-Joon, Kang, Dong-Wha, Lee, Jin Soo, Kwon, Sun U., Oh, Chang Wan, Lee, Byung-Chul, Yoon, Byung-Woo“…The public's knowledge of stroke definition, risk factors, warning signs, and act on stroke generally remains low. According to studies using open-ended questions, the correct definition of stroke was recognized in less than 50%, hypertension as a stroke risk factor in less than 50%, and other well-defined risk factors in less than 20%. …”
Publicado 2013
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431790por Banaschewski, Tobias, Soutullo, César, Lecendreux, Michel, Johnson, Mats, Zuddas, Alessandro, Hodgkins, Paul, Adeyi, Ben, A. Squires, Liza, Coghill, David“…A pivotal, 7-week, randomized, double-blind, placebo-controlled, phase III study in children and adolescents in ten European countries demonstrated that the stimulant prodrug lisdexamfetamine dimesylate (LDX) is an effective and generally well-tolerated treatment for symptoms of ADHD. …”
Publicado 2013
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431791por Munsters, Carolien C B M, van den Broek, Jan, Welling, Emile, van Weeren, René, van Oldruitenborgh-Oosterbaan, Marianne M Sloet“…BACKGROUND: Eventing is generally recognized as a challenging equestrian discipline and wastage figures for this discipline are relatively high. …”
Publicado 2013
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431792por Ebert, David Daniel, Gollwitzer, Mario, Riper, Heleen, Cuijpers, Pim, Baumeister, Harald, Berking, Matthias“…These findings may generalize to other Internet-based maintenance treatments. …”
Publicado 2013
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431793por Iitsuka, Hiromi, Tokuno, Tomoaki, Amada, Yoko, Matsushima, Hiroshi, Katashima, Masataka, Sawamoto, Taiji, Takusagawa, Shin, van Gelderen, Marcel, Tanaka, Takanori, Miyahara, Hideo“…Steady state was reached within 7 days. Mirabegron was generally well-tolerated at single doses up to 400 mg and multiple doses up to 200 mg. …”
Publicado 2013
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431794por Meng, Qiong, Bai, Xiangning, Zhao, Ailan, Lan, Ruiting, Du, Huamao, Wang, Tao, Shi, Changyou, Yuan, Xuejiao, Bai, Xuemei, Ji, Shaobo, Jin, Dong, Yu, Bo, Wang, Yan, Sun, Hui, Liu, Kai, Xu, Jianguo, Xiong, Yanwen“…Isolates of the same STs generally showed the same or similar drug resistance patterns. …”
Publicado 2014
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431795por Abel, K M, Heuvelman, H P, Jörgensen, L, Magnusson, C, Wicks, S, Susser, E, Hallkvist, J, Dalman, C“…The pattern of risk was generally similar for non-affective and affective psychosis. …”
Publicado 2014
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431796por Skowronski, Danuta M., Janjua, Naveed Z., De Serres, Gaston, Sabaiduc, Suzana, Eshaghi, Alireza, Dickinson, James A., Fonseca, Kevin, Winter, Anne-Luise, Gubbay, Jonathan B., Krajden, Mel, Petric, Martin, Charest, Hugues, Bastien, Nathalie, Kwindt, Trijntje L., Mahmud, Salaheddin M., Van Caeseele, Paul, Li, Yan“…BACKGROUND: Influenza vaccine effectiveness (VE) is generally interpreted in the context of vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to explain reduced protection. …”
Publicado 2014
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431797por Arvikar, Sheila L, Collier, Deborah S, Fisher, Mark C, Unizony, Sebastian, Cohen, George L, McHugh, Gail, Kawai, Toshihisa, Strle, Klemen, Steere, Allen C“…However, these patients generally had long-standing disease, and clinical associations with these antibodies were inconsistent. …”
Publicado 2013
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431798“…And the toxicities of amifostine were generally acceptable.…”
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431799por Kaku, Kohei, Watada, Hirotaka, Iwamoto, Yasuhiko, Utsunomiya, Kazunori, Terauchi, Yasuo, Tobe, Kazuyuki, Tanizawa, Yukio, Araki, Eiichi, Ueda, Masamichi, Suganami, Hideki, Watanabe, Daisuke“…CONCLUSIONS: Tofogliflozin 10, 20, or 40 mg administered once daily as monotherapy significantly decreased HbA(1c) and body weight, and was generally well tolerated in Japanese patients with type 2 diabetes mellitus. …”
Publicado 2014
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431800“…PRL elevations with antipsychotic medication generally are dose dependant. However, antipsychotics having a high potential for PRL elevation (amisulpride, risperidone and paliperidone) can have a profound impact on PRL levels even at relatively low doses, while PRL levels with antipsychotics having a minimal effect on PRL, in most cases, can remain unchanged (quetiapine) or reduce (aripiprazole) over all dosages. …”
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