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  1. 431801
    “…Factors associated with SubAdh were analysed using generalized estimating equations. RESULTS: Out of 1316 patients, 32% ever reported <100% adherence and 17% ever reported <95%. …”
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    Factors associated with suboptimal adherence to antiretroviral therapy in Asia
  2. 431802
    “…Recent improvements in procedures to purify and analyze very small numbers of human cells have generally supported this view, but have also revealed new complexities. …”
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    Online Artículo Texto
    Roles for the High Affinity IgE Receptor, FcεRI, of Human Basophils in the Pathogenesis and Therapy of Allergic Asthma: Disease Promotion, Protection or Both?
  3. 431803
    “…Although observational studies might suggest a simplistic hypothesis for high density lipoprotein cholesterol, that increasing the levels pharmacologically would generally reduce cardiovascular events, in the current era of widespread use of statins in dyslipidaemia, substantial trials of these three agents do not support this concept.…”
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    Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117 411 patients
  4. 431804
    por Chance, Steven A.
    Publicado 2014
    “…This account is mechanistic in the sense that it offers a mechanism whereby asymmetrical components of structure are related to specific functional biases yielding testable predictions, rather than the generalization that “bigger is better” for any given function. …”
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    The cortical microstructural basis of lateralized cognition: a review
  5. 431805
    “…Potential interactions with bisphenol A (BPA) a synthetic phenolic compound to which humans are generally exposed and a commonly used chemotherapeutic agent, doxorubicin (DOX) were also evaluated. …”
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    Cytotoxicity of Eupatorium cannabinum L. ethanolic extract against colon cancer cells and interactions with Bisphenol A and Doxorubicin
  6. 431806
    “…Diabetic foot treated improperly may lead not only to delayed ulceration healing, generalized inflammation, unnecessary surgical intervention, but also to the lower limb amputation. …”
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    Diabetic foot risk factors in type 2 diabetes patients: a cross-sectional case control study
  7. 431807
    “…CONCLUSIONS: In this 6-month, open-label extension study, treatment with lurasidone was generally well-tolerated with sustained improvement in efficacy measures observed in outpatients with schizophrenia or schizoaffective disorder who had switched to lurasidone from a broad range of antipsychotic agents.…”
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    Effectiveness of lurasidone in schizophrenia or schizoaffective patients switched from other antipsychotics: a 6-month, open-label, extension study
  8. 431808
    “…Repeated measures ANOVA and Generalized Estimating Equations (GEE) were used to evaluate longitudinal changes in QoL and SGA. …”
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    A longitudinal study investigating quality of life and nutritional outcomes in advanced cancer patients receiving home parenteral nutrition
  9. 431809
    “…However, the included trials were generally low in quality. More well-designed, high-quality trials are needed to provide better evidence for the assessment of the efficacy and safety of Chinese medicines for vascular dementia.…”
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    A meta-analysis of Chinese herbal medicines for vascular dementia
  10. 431810
    “…PRELIMINARY RESULTS: Formative research showed that women and their family members generally did not perceive birth spacing as a priority, and most recently delivered women were not using contraception. …”
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    Operations research to add postpartum family planning to maternal and neonatal health to improve birth spacing in Sylhet District, Bangladesh
  11. 431811
    “…Reduction in SMF with ATX-101 was confirmed by calliper measurements (p < 0.001 for both doses vs. placebo) and generally did not lead to worsening of skin laxity (SLRS improved or was unchanged: 91.3 and 90.5 % of the patients who received ATX-101 1 and 2 mg/cm(2), respectively, and 91.6 % of the placebo recipients). …”
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    Results from a Pooled Analysis of Two European, Randomized, Placebo-Controlled, Phase 3 Studies of ATX-101 for the Pharmacologic Reduction of Excess Submental Fat
  12. 431812
    “…Differences in treatments were assessed utilizing logistic regression, while differences in costs were analyzed using gamma-distributed generalized linear models with a log-link function. …”
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    Comparing Hospital-Based Resource Utilization and Costs for Prostate Cancer Patients With and Without Bone Metastases
  13. 431813
    “…Pretabalumab baseline disease activity was generally higher in the 60-mg/120-mg group. There was a higher frequency of serious adverse events and treatment-emergent adverse events, as well as infections and injection-site reactions, in the 60-mg/120-mg group. …”
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    A 52-week, open-label study evaluating the safety and efficacy of tabalumab, an anti-B-cell–activating factor monoclonal antibody, for rheumatoid arthritis
  14. 431814
    “…The relationship between changes in cerebral blood flow and arterial carbon dioxide tension is used to assess cerebrovascular function. Hypercapnia is generally evoked by two methods, i.e. steady-state and transient increases in carbon dioxide tension. …”
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    Cerebral vasomotor reactivity: steady-state versus transient changes in carbon dioxide tension
  15. 431815
    “…As expected, initiation rates of each intervention were higher in the groups determined to be at moderate/high CVD risk; however, within each high-risk group, initiation rates of most interventions (with the exception of anti-hypertensives) were generally lower in women than men. These gender differences persisted after adjustment for potential confounders (Table 1). …”
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    Gender differences in HIV-positive persons in use of cardiovascular disease-related interventions: D:A:D study
  16. 431816
    “…RPV-based regimen was generally well tolerated and only 6% of patients discontinued treatment for AEs. …”
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    Efficacy and safety of rilpivirine-based regimens in treatment-experienced HIV-1 infected patients: a prospective cohort study
  17. 431817
    “…Epigenetic alterations described in DIPG include global DNA hypomethylation. In addition to the generally repressive methylcytosine DNA alteration, 5-hydroxymethylation of cytosine (5hmC) is recognized as an epigenetic mark associated with active chromatin. …”
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    Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma
  18. 431818
    “…CONCLUSIONS: Young CMV seropositive children, especially those less than one year-old may present high-risk CMV exposures to pregnant women, especially via saliva, though further research is needed to see if this finding can be generalized across racial or other demographic strata. …”
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    Cross-sectional study of cytomegalovirus shedding and immunological markers among seropositive children and their mothers
  19. 431819
    “…Mean diffusivity was significantly lower in most white matter volumes of interest (P < 0.05, corrected for multiple comparisons), with a generally symmetric pattern of involvement in sporadic Creutzfeldt-Jakob disease. …”
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    White matter involvement in sporadic Creutzfeldt-Jakob disease
  20. 431820
    “…RESULTS: Based on the child’s own report, Roma children had a higher odds of any internalizing disorder (OR = 2.99, 95% C.I. 2.07–4.30), phobias (OR = 4.84, 95% C.I. 3.19–7.35), separation anxiety disorder (OR = 2.54, 95% C.I. 1.72–3.76), generalized anxiety disorder (OR = 2.95, 95% C.I. 1.75–4.96), and major depressive disorder (OR = 3.86, 95% C.I. 2.31–6.37). …”
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    Mental health disparities between Roma and non-Roma children in Romania and Bulgaria
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