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  1. 431821
    “…We found that the pathway leads to apoptosis in LNCaP cells, including the two androgen-independent LNCaP cell lines that are generally resistant to apoptosis. Lastly, we identified that FASTKD2-mediated apoptosis is initiated by the 81 amino acid FAST2 region. …”
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    Fas Activated Serine-Threonine Kinase Domains 2 (FASTKD2) mediates apoptosis of breast and prostate cancer cells through its novel FAST2 domain
  2. 431822
    “…CONCLUSIONS: N. gonorrhoeae isolates in Nanjing generally retained similar antimicrobial resistance patterns to isolates obtained five years ago. …”
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    Antimicrobial susceptibility of Neisseria gonorrhoeaeisolates from symptomatic men attending the Nanjing sexually transmitted diseases clinic (2011–2012): genetic characteristics of isolates with reduced sensitivity to ceftriaxone
  3. 431823
    “…For the post-intervention assessment, generalized estimating equations revealed a significant increase in the readiness to quit tobacco and cannabis in the total sample (B=.33, 95% CI 0.10-0.56, P=.006). …”
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    Effectiveness of Different Web-Based Interventions to Prepare Co-Smokers of Cigarettes and Cannabis for Double Cessation: A Three-Arm Randomized Controlled Trial
  4. 431824
    “…CONCLUSIONS: Very high academic scores generally required for medical school entry may have the unintended consequence of selecting fewer graduates interested in a rural practice destination. …”
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    Medical student selection criteria as predictors of intended rural practice following graduation
  5. 431825
    “…CONCLUSIONS: In cardiac surgery infants, EA produced more UO compared with F on POD0. Generally, a smaller EA dose is required to achieve similar UO than F. …”
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    Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial
  6. 431826
    “…CONCLUSION: The 2800 BAU Timothy grass SLIT-T significantly improved AR/C induced by Timothy grass pollen in adults and children ≥5 y in Canadians, which was consistent with the robust efficacy observed in the overall trial population. The treatment was generally well tolerated. TRIAL REGISTRATION: Clinicaltrials.gov identifiers NCT00562159, NCT00550550, NCT01385371.…”
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    The efficacy and safety of the Timothy grass allergy sublingual immunotherapy tablet in Canadian adults and children
  7. 431827
    “…METHODS: We test two methods for inferring Genetic Association Interaction Networks (GAIN) incorporating both differential co-expression effects and differential expression effects: a generalized linear model (GLM) regression method with interaction effects (reGAIN) and a Fisher test method for correlation differences (dcGAIN). …”
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    Differential co-expression network centrality and machine learning feature selection for identifying susceptibility hubs in networks with scale-free structure
  8. 431828
    “…Allogeneic third party T-cell donors offer an alternative option for patients receiving an allogeneic cord blood transplant or a transplant from a virus-seronegative donor and since donor blood is generally not available for solid organ recipients. …”
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    Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells
  9. 431829
    “…Four of the classes showed generally similar results across every day of the week, with the absolute percents differing across classes. …”
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    Physical activity and sedentary behavior patterns using accelerometry from a national sample of United States adults
  10. 431830
    “…BACKGROUND: Sinonasal cancer (SNC) has been related to occupational exposures, but the relative risk associated to specific jobs and/or carcinogen exposures other than wood and leather dust is generally based on small or inadequate sample sizes and the range of observed estimates is large. …”
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    Occupational exposure and sinonasal cancer: a systematic review and meta-analysis
  11. 431831
    “…BACKGROUND: HIE efforts have generally formed for the primary clinical use of individual clinical providers searching for data on individual patients under their care, but many secondary uses have been proposed and are being piloted to support care management, quality improvement, and public health. …”
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    The Visit-Data Warehouse: Enabling Novel Secondary Use of Health Information Exchange Data
  12. 431832
    “…We tested the application of standard mass balance corrections for isotope values that were significantly affected by the preservation methods and found generally poor agreement between corrected and control values. …”
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    Effects of preservation methods of muscle tissue from upper-trophic level reef fishes on stable isotope values (δ(13)C and δ(15)N)
  13. 431833
    “…CONCLUSIONS: Inter-rater reliability was generally poor to fair and test–retest reliability was fair to excellent. …”
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    Inter-rater and test–retest reliability of quality assessments by novice student raters using the Jadad and Newcastle–Ottawa Scales
  14. 431834
    “…CONCLUSION: Physician-recommended r-hFSH starting doses were generally higher than those calculated by CONSORT; most patients were prescribed a higher starting dose than that recommended by CONSORT.…”
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    Individualized recombinant human follicle-stimulating hormone dosing using the CONSORT calculator in assisted reproductive technology: a large, multicenter, observational study of routine clinical practice
  15. 431835
    “…The silencing mark H3K27me3 was generally present at the SOX11 promoter in non-expressing cells, and an increased enrichment was observed in cancer cells with a low degree of SOX11 methylation compared to cells with dense methylation. …”
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    DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells
  16. 431836
    “…CONCLUSION: [(18)F]FAZA tumor uptake was highest in ketamine/xylazine-anesthetized mice regardless of whether the mice breathed air or oxygen. The generally lower [(18)F]FAZA whole-body uptake in isoflurane-anesthetized mice could be due to the higher muscle pO(2)-values in these mice compared to ketamine/xylazine-anesthetized mice. …”
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    A Comparative pO(2) Probe and [(18)F]-Fluoro-Azomycinarabino-Furanoside ([(18)F]FAZA) PET Study Reveals Anesthesia-Induced Impairment of Oxygenation and Perfusion in Tumor and Muscle
  17. 431837
    “…The treatment should cover both diseases. Generally, the therapy should include at least inhaled glucocorticoids (beclomethasone dipropionate, budesonide, ciclesonide, fluticasone furoate, fluticasone propionate or mometasone) combined with a long-acting bronchodilator (β(2)-agonist or anticholinergic or both).…”
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    Diagnosis and Pharmacotherapy of Stable Chronic Obstructive Pulmonary Disease: The Finnish Guidelines
  18. 431838
    “…Baseline characteristics were generally similar between groups overall and within each stratification. …”
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    Insulin degludec in combination with bolus insulin aspart is safe and effective in children and adolescents with type 1 diabetes
  19. 431839
    por Grünbaum, Daniel, Willis, Mark A
    Publicado 2015
    “…Success in contests of risk-averse vs. risk-tolerant behaviors varies strongly with the number of competitors, suggesting empirically testable predictions for diverse plume-following taxa. More generally, spatial memory-based models provide tractable, explicit theoretical linkages between sensory biomechanics, neurophysiology and behavior, and ecological and evolutionary dynamics operating at much larger spatio-temporal scales. …”
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    Spatial memory-based behaviors for locating sources of odor plumes
  20. 431840
    “…Single- and multi-site GS prediction models were developed using the Ridge Regression Best Linear Unbiased Predictor (RR-BLUP) and the Generalized Ridge Regression (GRR) to test different assumption about trait architecture. …”
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    Prediction accuracies for growth and wood attributes of interior spruce in space using genotyping-by-sequencing
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