“…Case 26 year old woman, presented to the emergency department at 22 weeks of gestation with complaints of generalized weakness, fatigue, increased thirst, constipation, and intermittent right lower quadrant abdominal pain for 2 weeks. …”
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“…RCC is an uncommon and usually asymptomatic intrasellar lesion, but pituitary dysfunction has been reported in 39% to 100% of these cases with prolactin levels generally less than 200 ng/mL. This hyperprolactinemia has been postulated to occur due to pituitary stalk compression from the sellar mass causing a decrease in dopamine (prolactin inhibitor) delivery. …”
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“…She developed persistent severe hypocalcemia with ionized calcium of 3.7mg/dl (normal range 4.5-5mg/dl) and total serum calcium of 6.1mg/dl (normal range 8.4-10mg/dl) associated with generalized weakness and perioral numbness and tingling which was treated with high doses of calcitriol and intravenous calcium gluconate. …”
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“…Introduction: Severe Hypocalcaemia is generally seen in clinical practice in patients following thyroid or parathyroid surgery .We report a case of severe hypocalcaemia with unusual presentation and etiology with challenging management. …”
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“…Patient referred that 1 week before arrival to the hospital developed a generalize weakness associated with anorexia, nausea, vomits, polydipsia and polyuria. …”
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“…Two main analyses were conducted: 1) a comparison between control and protocol groups in terms of the proportion of high BG readings (i.e.BG>200) using generalized estimating equations (GEE) logistic regression and 2) a comparison between pre- and post-protocol BG readings in protocol patients who started protocol more than 48 hours after first steroid administration using Wilcoxon’s exact signed rank test. …”
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“…Clinical Case: A 72-year-old woman was admitted to the acute frailty ward with symptoms of generalized weakness, fatigue and reduced exercise tolerance with shortness of breath on exertion. …”
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“…Case 77-year-old male with metastatic choroidal melanoma treated with two cycles of Ipilimumab and Nivolumab presented to the hospital with two-week history of generalized weakness, malaise, loss of appetite, and 20 lb weight loss. …”
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“…Results from the open-label Phase 2 study (NCT02804750) indicated that treatment with RELA was generally well tolerated and significantly improved glycemic and hypertension control in patients with endogenous hypercortisolism. …”
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“…Clinical Case: A 56-year-old female with a history of endocervical adenocarcinoma stage IVb metastatic to the peritoneum, lung, and bone and CKD stage III presented to the emergency department with symptoms of generalized pain, nausea and lethargy. Patient was diagnosed with endocervical adenocarcinoma 4 months prior to presentation and was treated with 2 cycles of chemotherapy (carboplatin/paclitaxel). …”
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“…Conclusion: EuDKA is defined as diabetic ketoacidosis without marked hyperglycemia, generally <300 mg/dL. The association between euDKA and SGLT2i is presumably due to increased urinary excretion of glucose with diminished glycogen stores, compounded by increased ketone production and impaired excretion. …”
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“…Case Presentation Caucasian 23 year old female presented with fatigue, generalized weakness, and severe muscle aches only bilaterally in upper extremities with low grade fever and numbness in arms and legs for 5 weeks, preceded by upper respiratory infection treated with Levaquin with no improvement. …”
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“…Conclusions: The case highlights, generally, that TFTs can be unreliable in an acute illness, and that seizures may cause an acute, transient rise in TSH. …”
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“…The orbital expression of the thyroid stimulating hormone receptor (TSHR) has been implicated in this condition which generally occurs in hyperthyroid patients due to Graves’ disease. …”
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“…Case 2: A 48-year-old man was evaluated for erectile dysfunction and generalized muscle weakness. Past history and family history were noncontributory. …”
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“…She was also noted to have craniosynostosis at birth, and developed generalized tonic-clonic seizures at age 3 months, necessitating phenobarbital therapy for 4 years. …”
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“…CT scan of the brain showed disseminated intracranial cortical and basal ganglia calcifications, consistent with Fahr syndrome. EEG showed generalized background slowing compatible with mild diffuse cerebral dysfunction. …”
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“…Clinical Case: A 59-year-old woman presented with symptoms of polydipsia, polyuria, unquantifiable weight loss, and generalized body weakness. Initial assessment showed evidence of panhypopituitarism as per: FT4 0.39 (0.60-1.32 ng/dL), TSH 1.39 (0.45-5.33 uIU/mL), Cortisol 1.8 (6.7-22.6 ug/dL), ACTH 13 (6-50 pg/mL), Prolactin 223.5 (2.74-19.64 ng/mL), Estradiol 222 (<= 31 pg/mL) while on estradiol pellets, LH 0.2 (10.87-58.64 mIU/mL), FSH 1.6 (16.74-113.59 mIU/mL), Na 146 mmol/L, Cl 112 mmol/L, and urine specific gravity 1.004. …”
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“…It is due to impaired lipoprotein lipase (LPL) function, typically caused by bi-allelic LPL loss-of-function mutations. Although FCS generally presents in childhood with acute pancreatitis and HTG, it should also be considered as a diagnosis in adults with severe HTG. …”
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“…Associations of iron status indicators with breast cancer risk were generally in the positive direction; however, a significant pooled RR was found only for serum/plasma levels (highest vs. lowest) of iron (1.22, 95% CI: 1.01–1.47), but not for ferritin (1.13, 95% CI: 0.78–1.62), transferrin saturation (1.16, 95% CI: 0.91–1.47), or total iron-binding capacity (1.10, 95% CI: 0.97–1.25). …”
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