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  1. 432941
    “…INTRODUCTION: H3K27M-mutant diffuse midline gliomas (H3K27M-DMGs) share a generally poor prognosis with a median overall survival (OS) of 9–12 months. …”
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    DIPG-26. CLINICAL AND GENOMIC ANALYSIS OF H3K27M-DMG LONG-TERM SURVIVORS REVEALS ENRICHMENT IN MAPK PATHWAY ALTERATIONS
  2. 432942
    “…MAIN OUTCOMES AND MEASURES: The main outcomes were birth certificate birth weight measures including small for gestational age (SGA), large for gestational age (LGA), and sex-specific birth weight for gestational age z-score. Generalized linear mixed-effects models and hierarchical linear models estimated risk ratios for associations between density of neighborhood-level characteristics within a 1-km buffer of residential census block centroid and birth weight outcomes. …”
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    Neighborhood Food Environment and Birth Weight Outcomes in New York City
  3. 432943
    “…The effect of the period on the burden of T2DM attributable to a high BMI increased from 1990 to 2019. The cohort effect generally showed a downward trend. CONCLUSION: The burden of T2DM attributed to a high BMI in China increased substantially from 1990 to 2019, particularly in men. …”
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    Trends of the burden of type 2 diabetes mellitus attributable to high body mass index from 1990 to 2019 in China
  4. 432944
    “…Sows mobilize body reserves during gestation and lactation due to nutrients being prioritized for lactation purposes while feeding piglets, which generally leads to metabolism and immunity undergoing drastic changes. …”
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    Fermented Bamboo Fiber Improves Productive Performance by Regulating Gut Microbiota and Inhibiting Chronic Inflammation of Sows and Piglets during Late Gestation and Lactation
  5. 432945
    “…CONCLUSION: Our findings suggest that the SN may be entrained by temporal lobe seizures secondary to the SI during the farther spreading of LAF seizures, which supports the theory that the SN plays a role in the generalization and/or maintenance of temporal lobe seizures and helps explains the anti-ictogenic effect of SN inhibition.…”
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    The Entrainment of the Substantia Nigra During Temporal Lobe Seizures is Dependent on the Seizure Onset Pattern
  6. 432946
    “…The rDNA ITS region is generally applied as classical barcoding gene for fungi. …”
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    Mortierellaceae from subalpine and alpine habitats: new species of Entomortierella, Linnemannia, Mortierella, Podila and Tyroliella gen. nov.
  7. 432947
    “…The clinical outcomes were measured by the self-reported PHQ-9 instrument to assess changes in depressive symptoms scored as depression-related severity, clinical remission, and clinical response. A generalized estimating equation (GEE) model was fitted to examine changes in composite PHQ-9 scores from baseline to the final session. …”
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    Effectiveness of the Program to Encourage Active, Rewarding Lives (PEARLS) to reduce depression: a multi-state evaluation
  8. 432948
    “…The performance was generally consistent in the training and the two validation cohorts. …”
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    A panel of seven protein tumour markers for effective and affordable multi-cancer early detection by artificial intelligence: a large-scale and multicentre case–control study
  9. 432949
    “…After a single vaccination, VLA1553 induced seroprotective chikungunya virus neutralising antibody levels in 263 (98·9%) of 266 participants in the VLA1553 group (95% CI 96·7–99·8; p<0·0001) 28 days post-vaccination, independent of age. VLA1553 was generally safe with an adverse event profile similar to other licensed vaccines and equally well tolerated in younger and older adults. …”
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    Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind, multicentre, randomised, placebo-controlled, phase 3 trial
  10. 432950
    “…Descriptive statistics were used to analyze the quantitative data, while the qualitative data was analyzed thematically. RESULTS: Generally, 59.2% of participants indulged in alcohol consumption. …”
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    Alcohol consumption and risky sexual behaviors among fishers in Elmina in Ghana
  11. 432951
    “…Extant systematic literature reviews within this area of research have not yet focused on university students or anxiety, rather predominantly investigating adolescents or generalized mental health symptoms and disorders. Furthermore, there is little to no qualitative data exploring the association between social media and anxiety among university students. …”
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    Exploring the Impact of Social Media on Anxiety Among University Students in the United Kingdom: Qualitative Study
  12. 432952
    “…The effect of the overall intervention on step counts relative to baseline will be examined using generalized linear mixed models with an autoregressive model that accounts for possible autocorrelation and linear trends for daily steps across time. …”
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    Testing Behavior Change Techniques to Increase Physical Activity in Middle-Aged and Older Adults: Protocol for a Randomized Personalized Trial Series
  13. 432953
    “…CONCLUSIONS: Social media was an effective means to inform applicants, and generally positively impacted applicants’ perception of programs. …”
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    Influence of Social Media on Applicant Perceptions of Anesthesiology Residency Programs During the COVID-19 Pandemic: Quantitative Survey
  14. 432954
    “…The participants also completed an exit survey after all 5 game sessions (modified version of the Patient Health Questionnaire and the Generalized Anxiety Disorder Questionnaire, and 17 open-ended questions). …”
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    Evaluating the Feasibility of a Multiplayer Role-Playing Game as a Behavioral Health Intervention in Adolescent Patients With Chronic Physical or Mental Conditions: Protocol for a Cohort Study
  15. 432955
    “…Okhotoside A(1)-1 was the most active compound from the series because of the presence of a tetrasaccharide linear chain and holostane aglycone with a 7(8)-double bond and 16β-O-acetoxy group, cucumarioside A(0)-1, having the same aglycone, was slightly less active because of the presence of branching xylose residue at C-2 Qui2. Generally, the activity of the djakonoviosides of group A was higher than that of the djakonoviosides of group B containing the same aglycones, indicating the significance of a linear chain containing four monosaccharide residues for the demonstration of membranolytic action by the glycosides. …”
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    Djakonoviosides A, A(1), A(2), B(1)–B(4) — Triterpene Monosulfated Tetra- and Pentaosides from the Sea Cucumber Cucumaria djakonovi: The First Finding of a Hemiketal Fragment in the Aglycones; Activity against Human Breast Cancer Cell Lines
  16. 432956
    “…EAR and cumulative incidence trends generally were similar to SIR trends. Median survival after tMDS/AML was 8.0 months (interquartile range, 3.0–22.0). …”
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    Trends in risk for therapy-related myelodysplastic syndrome/acute myeloid leukemia after initial chemo/immunotherapy for common and rare lymphoid neoplasms, 2000–2018
  17. 432957
    “…The present study systematically compares the sensitivity and selectivity of the analysis of multiple vitamin D metabolites after chemical derivatization using different reagents for liquid chromatography-tandem mass spectrometry (LC–MS/MS). Generally, chemical derivatization is applied to vitamin D metabolites to increase the ionization efficiency, which is particularly important for very low abundant metabolites. …”
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    Comparing derivatization reagents for quantitative LC–MS/MS analysis of a variety of vitamin D metabolites
  18. 432958
    “…Gait semantics could then be obtained from the frame labels, and all the gait parameters could be calculated accordingly. For optimal generalization performance of the model, the classifiers were trained using a 10-fold cross-validation strategy. …”
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    Deep Learning–Assisted Gait Parameter Assessment for Neurodegenerative Diseases: Model Development and Validation
  19. 432959
    “…MAIN OUTCOMES AND MEASURES: A central study site remotely administered a onetime neurological examination and in-depth neuropsychological assessment including measures of cognition, behavior, quality of life, and daily function. Generalized estimating equations, accounting for matching, assessed for group differences. …”
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    Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children
  20. 432960
    “…Although PFMT parameters and program compliance varied, most studies that reported on UI symptoms showed improved outcomes, and women were generally satisfied with this treatment approach. With respect to life stage, pregnancy and the postpartum period were the most common focus, with more evidence needed for women of various age ranges (eg, adolescent and older women), including their cultural context, which is a factor that is rarely considered. …”
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    Digital Technologies for Women’s Pelvic Floor Muscle Training to Manage Urinary Incontinence Across Their Life Course: Scoping Review
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