“…MMR system assessments in ACCs involve a low level of statistical evidence. Generally, there are two main types of endocrine insights: 1. the role of MMR status as a prognostic marker in different endocrine malignancies (including ACC)—which is the topic of the present work, and 2. establishing the indication of immune checkpoint inhibitors (ICPIs) in selective, mostly highly aggressive, non-responsive to standard care forms upon MMR evaluation (which belongs to the larger chapter of immunotherapy in ACCs). …”
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“…ADA test did not detect any anti-HFB30132A antibodies Conclusion: HFB30132A was safe and generally well-tolerated after single IV dose of 1,000 mg or 2000 mg in healthy Chinese adults. …”
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“…Furthermore, our study only included a Chinese population, therefore caution is required regarding generalization of our findings to other populations. WIDER IMPLICATIONS OF THE FINDINGS: Dietary phytochemicals, namely carotene, lutein, and zeaxanthin, might exert a positive effect on teratozoospermia. …”
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“…OBJECTIVE: To develop and validate an AI model (Standardized Computer-based Organized Reporting of EEG–Artificial Intelligence [SCORE-AI]) with the ability to distinguish abnormal from normal EEG recordings and to classify abnormal EEG recordings into categories relevant for clinical decision-making: epileptiform-focal, epileptiform-generalized, nonepileptiform-focal, and nonepileptiform-diffuse. …”
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“…OBJECTIVES: To develop an intuitive and generally applicable system for the reporting, assessment, and documentation of ADC to complement standard BI-RADS criteria. …”
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“…The World Health Organization (WHO) definitions were used for classification of infant breastfeeding practices. Generalized linear models of the Poisson family with a log-link function were used to estimate the effect of interventions on breastfeeding practices. …”
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“…Measures included demographics, web-based LGBT identity disclosure, hours per week spent on LGBT social media sites, engagement in web-based social justice activities (Online Civic Engagement Behavior Construct), exposure to web-based discrimination (Online Victimization Scale), web-based social support (adapted from scales examining web-based interactions), depressive and anxiety symptoms, and substance use (the Patient Health Questionnaire modified for Adolescents; Generalized Anxiety Disorder 7-item; and Car, Relax, Alone, Forget, Friends, Trouble Screening Test). …”
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“…Third, the data obtained were modeled using 5 machine learning algorithms, namely, logistic regression, automatic generalized linear model, automatic random forest, automatic deep neural network, and automatic gradient boosting machine, to identify and investigate factors affecting web-based medical record nonuse. …”
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“…Univariate correlation analysis revealed that HT [LASr, r=−0.53, 95% confidence interval (CI): −0.62 to −0.42, P<0.001; LAScd, r=−0.49, 95% CI: −0.58 to −0.39, P<0.001; and LASct, r=−0.46, 95% CI: −0.55 to −0.34, P<0.001] and BMI categories (LASr, r=−0.68, 95% CI: −0.75 to −0.61, P<0.001; LAScd, r=−0.47, 95% CI: −0.57 to −0.35, P<0.001; and LASct, r=−0.73, 95% CI: −0.78 to −0.66, P<0.001) were negatively correlated with LA strains. A generalized linear model further demonstrated that there was an interaction effect between HT and obesity on LA strains after adjusting for confounding factors (Model 2: LASr, β(HT*Obesity) =−1.91, 95% CI: −3.48 to −0.35, P=0.01; LAScd, β(HT*Obesity) =−3.26, 95% CI: −4.83 to −1.70, P<0.001; LASct, β(HT*Overweight) =−1.97, 95% CI: −3.03 to −0.91, P<0.001; β(HT*Obesity) =−1.54, 95% CI: −2.67 to −0.41, P=0.007). …”
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“…Data will be analyzed using generalized estimating equations. RESULTS: Final development and testing of the LinkPositively app were completed in July 2021. …”
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“…Secondary outcomes included changes in depression (Patient Health Questionnaire-9) and anxiety (Generalized Anxiety Disorder-7) scores as well as treatment attendance, satisfaction, and perceived helpfulness. …”
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“…Billed annualized bleed rates, health care resource utilization, and annualized costs were evaluated. Generalized linear models compared annualized total costs in the hemophilia A carrier and control groups. …”
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“…The index date was defined as the first fill for a medication included in the PQA PDC Diabetes All Class adherence measure after a 180-day baseline period. Generalized linear models with log link and gamma distribution (expenditure) or negative binomial distribution (utilization) assessed relationships between adherence (≥ 80% PDC) and health care utilization and expenditure while adjusting for potential confounders. …”
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“…Over the same periods, medical costs generally accounted for > 50% of total health care costs for patients who initiated ART between > 60 and ≤ 180 days and > 180 and ≤ 360 days and for 30%-40% of total health care costs for patients treated ≤ 14 days and between > 14 and ≤ 60 days. …”
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“…Kaplan-Meier curves and Cox proportional hazard models were used to evaluate TTNT, and generalized linear models were used to determine all-cause per patient per month (PPPM) HRU and costs during 1L among propensity score-matched (PSM) cohorts. …”
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“…While the National Collegiate Athletic Association (NCAA) has yet to enforce a pitch count rule for participating baseball teams, multiple organizations including the MLB’s Pitch Smart provide age-based guidelines for limiting risk of injury in baseball pitchers through utilization of pitch count limits and rest time. These are generally enforced for youth and high school baseball players. …”
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“…Adherence (proportion of days covered) and hospital visits were assessed at 12, 24, and 36 months for patients with sufficient follow-up data. Multivariable generalized models estimated differences between cohorts, controlling for baseline characteristics and hospital visits. …”
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“…Overall, 18 perceived impacts were identified. Generally, a greater number of positive impacts were reported in health care systems of higher digital health maturity. …”
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“…For small training sets, which are common with FAS, boosting mechanisms like CatBoost may help alleviate certain problems associated with data imbalances and difficulties in optimization or generalization.…”
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“…For hypothesis testing, we compared IPT-adjusted differences in quarterly costs between treatment groups using Mann-Whitney U-tests and generalized estimating equation (GEE) regression models. …”
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