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  1. 434461
    “…Subjects with LD (N=24, 75% female; 8 generalized, 16 partial) had a more atherogenic lipoprotein profile vs INSR (N=12, 50% female; 6 homozygous, 6 heterozygous), with 45-fold higher large TRLP, 20-fold higher medium TRLP, 15-fold higher very small TRLP (representing IDL), 3-fold higher small LDLP, 4-fold lower large HDLP, 1.7—fold higher ApoB, and 1.4—fold lower ApoAI (p <0.05 for all). …”
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    THU335 Hyperinsulinemia Is Associated With An Atherogenic Lipoprotein Profile In Humans With Selective Insulin Resistance And An Atheroprotective Profile In Humans With Non-selective Insulin Resistance
  2. 434462
    “…When comparing GHR-KO visceral to WT, terms associated with IGF signaling and longevity regulation had decreased expression, while immune activation and cell motility were increased. Pathway analysis generally agreed with these results, but also showed a decrease in multiple signaling pathways including AMPK and PI3K-Akt in both depots. …”
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    THU051 GH Resistance And Adipose Tissue: Multispecies Measurement Of Morphology And Transcriptome
  3. 434463
    “…Mitotane has been used for the treatment of advanced ACC since the 1960s and is generally recommended to reduce risk of future recurrence. …”
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    FRI199 Severe Hypertriglyceridemia And Acute Pancreatitis In A Patient With Adrenocortical Carcinoma (ACC) Taking Mitotane
  4. 434464
    “…After 7 months of holding Keytruda, on routine blood work he had a critically low calcium level of 5.5 mg/dl (8.4-10.2 mg/dl) with tingling and numbness in his hands, muscle spasms, generalized weakness, and fatigue for the past few weeks. …”
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    SAT220 Rare Case Of Pembrolizumab Induced Primary Hypoparathyroidism
  5. 434465
    “…Associations between PCOS status and traits were evaluated using generalized linear regression models. All p-values were BMI adjusted. …”
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    THU632 Musculoskeletal Composition And Function In Polycystic Ovary Syndrome: Early Evidence From A Prospective Study
  6. 434466
    por Akhter, Wajeeha, Gilden, Janice L
    Publicado 2023
    “…Upon evaluation, she had fatigue, lethargy, generalized muscle weakness, but denied headaches, fractures, abdominal pain, galactorrhea, and vaginal dryness. …”
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    SAT346 Empty Sella Syndrome And Hypopituitarism In A Childhood Cancer Survivor
  7. 434467
    “…This gene is associated with congenital hyperinsulinemia causing hypoglycemia, generally when in homozygous state. This clinical report illustrates a new phenotype associated with ABCC8 mutation, and identifies a new genetic cause of hyperinsulinemic pseudoacromegaly. …”
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    THU182 Widening The Spectrum Of ABCC8-related Disease: Insulin-mediated Pseudoacromegaly
  8. 434468
    “…He also complained of generalized muscle weakness. His total alkaline phosphatase (ALP) levels were noted to be increased for many years. …”
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    THU463 Etiology Of Hypophosphatemia In A Patient With Co-existing Mesenchymal Tumor And Fibrous Dysplasia
  9. 434469
    “…She presented with symptoms of tingling over bilateral lower extremities and generalized weakness causing dizziness and fall at home. …”
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    THU447 Hungry Bone Syndrome Secondary To Denosumab Use In A Patient With Sleeve Gastrectomy
  10. 434470
    “…Both DKA and HHS are hyperosmolar states most commonly triggered by infections[3], but in HHS, osmolarity generally exceeds 320mmol/l, free water deficit is more profound. …”
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    THU379 A Case Of Hyperglycemia With Severe Anion Gap Metabolic Acidosis: HHS Vs DKA
  11. 434471
    “…The right ovarian vein is generally harder to sample than the left. Results were consistent with androgen hypersecretion on the right (right: total testosterone 5,817 ng/dL, androstenedione >40 ng/mL, DHEA-S 20.084 ng/mL; left: total testosterone 189 ng/dL, androstenedione 1.798 ng/mL, DHEA-S 1.893 ng/mL). …”
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    SAT360 Ovarian Vein Sampling in a Pre-menopausal Woman with Hyperandrogenism: Characterization of Hormonal Profiles
  12. 434472
    “…In 20-25% of children, the difficulties interfere “a medium amount”, to “a great deal” at home (45, 26%), with friends (32, 19%), and at school (47, 27%). The difficulties generally don’t upset the children (127, 74% “not at all” or “only a little”) or place a significant burden on families (136, 79% “not at all” or “only a little”). …”
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    THU229 Assessing The Effect Of The Changing Levels Of Restrictions Placed By The COVID-19 Pandemic On Children And Their Behaviors
  13. 434473
    “…Case: 82-year-old female with a history of DM type 2 on metformin and hypertension presented to the Emergency Department (ED) with complaints of presyncope, vomiting and generalized weakness for two weeks. In the ED, her temp. was 90.3 F and BP was 66/28 mmHg. …”
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    THU382 It’s Not What It Seems - Metformin Induced Severe Lactic Acidosis Mimicking Euglycemic Diabetic Ketoacidosis
  14. 434474
    por Kutchukhidze, Tinatin, Khurodze, Tea
    Publicado 2023
    “…A thyroid scan with Tc99m revealed generalized increased uptake. Laboratory investigations showed a decrease in TSH-<0.005mIU/ml (n.0.4mIU/ml - 4.0mIU/ml), elevated FT4-31.8 pmol/l (n.8.0pmol/l-22.0pmol/l), FT3- 9.69pmol/l (n3.4 pmol/l-6.76pmol/l) and positive Anti-TG -190.05 AU/ml (n>150), Anti-TPO -75.7 IU/ml (n>75) Anti-TSHR-27.3 IU/l (n>1,5). …”
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    FRI558 Hidden Cause Of Decreased Fertility Rate During Grave’s Disease
  15. 434475
    por Akanbi, Folake, Raja, Sobia, Else, Tobias
    Publicado 2023
    “…During chemotherapy planning, metastases were noted, mitotane and pembrolizumab were initiated, but discontinued after 2 cycles on account of generalized rash and elevated liver enzymes. The tumor progressed on etoposide, doxorubicin and cisplatin (EDP), and second line therapy (gemcitabine and capecitabine) was initiated. …”
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    SAT337 Maternal Cell free DNA Testing Reveals Incidental Finding Of Adrenocortical Carcinoma
  16. 434476
    “…The diagnosis of sarcopenia was defined by low muscle mass with low muscle strength and/or reduced physical performance. Generalized additive analyses and dose‐dependent analyses with three models were used to assess the effects of different pattern of cooking and heating on muscle and sarcopenia. …”
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    Associations between indoor air pollution for cooking and heating with muscle and sarcopenia in Chinese older population
  17. 434477
    “…HaploView v.5.0 and generalized multifactor dimensionality reduction (GMDR) analysis were employed for haplotypic assignment and gene-environment interaction analyses. …”
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    Interactive effects between CDHR3 genotype and rhinovirus species for diagnosis and severity of respiratory tract infections in hospitalized children
  18. 434478
    “…The PHQ-2 is composed of the first 2 questions of the PHQ-9 (targeting core depression symptoms of depressed mood and anhedonia; a score of 3 or higher (score range, 0-6) is generally considered a positive depression screen. …”
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    Validity of the Spanish-Language Patient Health Questionnaires 2 and 9: A Systematic Review and Meta-Analysis
  19. 434479
    “…METHODS: Eligible participants (N=18,626) were adults aged 18 years and older who were enrolled in myStrength for at least four weeks as part of their employee wellness benefit program, who completed baseline, the 2-week, 2-month, and 6-month surveys querying symptoms of anxiety (Generalized Anxiety Disorder–7 [GAD-7]) and depression (Patient Health Questionnaire–9 [PHQ-9]). …”
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    The Effect of a Digital Mental Health Program on Anxiety and Depression Symptoms: Retrospective Analysis of Clinical Severity
  20. 434480
    “…In the pilot study, young people were assessed for symptoms of depression or anxiety using standard self-report clinical measures: the Patient Health Questionnaire-8 and the Generalized Anxiety Disorder-7 scales. Teenagers endorsing symptoms of depression or anxiety (n=14) were paired with a mentor (n=10) based on preferred characteristics such as gender, race or ethnicity, and lesbian, gay, bisexual, transgender, queer (LGBTQ) status. …”
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    The Appa Health App for Youth Mental Health: Development and Usability Study
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