“…However, the methodological quality of the randomized controlled trials was generally low. Larger and better-designed randomized controlled trials are required to more reliably assess the clinical effectiveness of HGWWD.…”
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“…The advantages of the proposed method lie in the following aspects: firstly, it can extract the vessels with poor angiography quality, since the multi-scale filtering algorithm can improve the vessel intensity in the circumstance such as uneven contrast media and bias field; secondly, it performed well for extracting the vessels in multi-modality angiographic images despite various signal-noises; and thirdly, it was implemented with better accuracy, and robustness than the traditional methods. Generally, these traits declare that the proposed method would have significant clinical application.…”
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“…Balanced patients’ samples were obtained by a generalized propensity score to adjust for baseline differences. …”
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“…We focus on the [Formula: see text] topography of biomarker hydrocarbons, hopanes and steranes, as they are generally recalcitrant to weathering. We introduce peak topography maps (PTM) and topography partitioning techniques that consider a notably broader and more diverse range of target and non-target biomarker compounds compared to traditional approaches that consider approximately 20 biomarker ratios. …”
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“…At 6-month follow-up, the improvements in the intervention group were generally sustained. CONCLUSIONS: This study shows that the online self-help CDMIs have a positive impact on various mental health outcomes. …”
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“…The mean number of Gd-enhanced T1 and new/newly enlarged T2 lesions decreased up to month 9 and thereafter remained low until the end of study (0.0–0.1 and 0.0–0.3, respectively, across all assessment time points after switch up to end of study). Fingolimod was generally well-tolerated and the safety profile was consistent with the core and 6-month extension. …”
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“…Findings from this study should be interpreted cautiously as they cannot be generalized to the entire population of HIV-infected patients in KwaZulu-Natal. …”
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“…Statistical methods used were multivariate logistic regression and logistic generalized estimating equation. RESULTS: Sixty-eight participants completed the short-term follow-up at 3 months, and 53 participants completed the long-term follow-up at 15 months. …”
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“…To examine changes in ATCIQ scores and Internet use over time, we used generalized estimating equations. We also collected qualitative data during intervention delivery. …”
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“…Therefore, it is implemented with better accuracy and robustness than the traditional methods. Generally, these traits declare that the proposed RSBF would have significant clinical application.…”
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“…Furthermore, in our environment, the term technology is generally reserved for its technical component. This terminology essentially means not only the purchase of the computer and related equipment, but also the technological foresight and technological progress, which are defined as specific combination of fundamental scientific, research and development work that gives a concrete result. …”
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“…METHODS: People with depressive or anxious symptoms (N=176) seeking entry into a trial of mental health and well-being apps for Android devices completed online questionnaires assessing depression and anxiety (Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7), past and current mental health treatment-seeking behavior, overall mobile device use, and use of mobile health apps. …”
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“…Upper gastrointestinal bleeding is a serious complication, but had low case fatality in trials of aspirin and is not generally thought to cause long-term disability. Consequently, although co-prescription of proton-pump inhibitors (PPIs) reduces upper gastrointestinal bleeds by 70–90%, uptake is low and guidelines are conflicting. …”
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“…Because shoulder range of motion is generally measured 5 degrees intervals in the orthopaedics. …”
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“…Seventy-eight percent of patients reported TEAEs and 22.8% of patients discontinued due to TEAEs. TEAEs were generally mild to moderate in intensity (96.5%). CONCLUSIONS: TDB provides effective pain relief with an acceptable tolerability profile over the 11-week treatment period in Asian patients with chronic musculoskeletal pain. …”
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“…Assessments were completed offline via self-assessment questionnaires at enrolment (mean child age=4.1 weeks, SD 1.3) and again when infants were aged 9, 15, and 21 months. RESULTS: Generalized estimating equations adjusting for post-randomization baseline imbalances showed that differences in outcomes between mothers in the clinic+Internet and home-based support groups did not exceed the pre-specified margin of inferiority (0.25 of a SD) on any outcome measure at any follow-up assessment, with the exception of MCDI scores assessing children’s language development at 21 months for randomized mothers, and PSI Isolation scores at 9 months for preference mothers. …”
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“…Angular deformity (valgus) occurred as well but was generally observed. Although there traditionally has been a concern for growth disturbance in very young patients (under 12 in males, under 10 in females) who undergo reconstruction, patients who are nearing skeletal maturity may actually be at higher risk of clinically significant growth disturbances due decreased ability for the body to respond to physeal insult.…”
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“…BACKGROUND: In Peru’s urban communities, tobacco smoking generally starts during adolescence and smoking prevalence is highest among young adults. …”
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“…In assessment of renal and bone safety using estimated glomerular filtration rate (eGFR), renal biomarkers, and BMD, there were differences between two arms that generally favored FTC/TAF over FTC/TDF (Table). In the overall population, no cases of Fanconi syndrome or proximal renal tubulopathy occurred with FTC/TAF; one FTC/TDF participant discontinued study drug due to proximal tubulopathy. …”
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“…The ST131-associated IncF[F2:A1:B-] plasmids from NC generally resembled those from other US regions (Figure 2). …”
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