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435001por Naik, Jaesh, Beavers, Norma, Nilsson, Fredrik O. L., Iadeluca, Laura, Lowry, Chrissy“…Probabilistic results were generally consistent with deterministic results, and one-way sensitivity identified NMA HRs, alectinib and brigatinib treatment duration, and the CNS-progressed utility multiplier as key model drivers. …”
Publicado 2023
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435002por Li, Xin, Hu, Banglian, Guan, Xiaoyan, Wang, Ziwei, Zhou, Yuhang, Sun, Hao, Zhang, Xian, Li, Yanfang, Huang, Xiaohua, Zhao, Yingjun, Wang, Xin, Xu, Huaxi, Zhang, Yun-Wu, Wang, Zhanxiang, Zheng, Honghua“…Although the molecular mechanism underlying CSF1R-mediated microgliopathy remains unclear, therapeutic strategies have generally targeted modulation of microglial function. …”
Publicado 2023
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435003por Cao, Xingqi, Li, Xueqin, Zhang, Jingyun, Sun, Xiaoyi, Yang, Gan, Zhao, Yining, Li, Shujuan, Hoogendijk, Emiel O, Wang, Xiaofeng, Zhu, Yimin, Allore, Heather, Gill, Thomas M, Liu, Zuyun“…Robust results were generally observed in sensitivity analyses. CONCLUSIONS: In UK Biobank participants with prediabetes, both prefrailty and frailty are significantly associated with higher risks of multiple adverse outcomes, including T2DM, diabetes-related diseases, and all-cause mortality. …”
Publicado 2023
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435004por Kemp, Byron J., Dumuid, Dorothea, Chong, Kar Hau, Parrish, Anne-Maree, Cliff, Dylan“…CONCLUSIONS: Non-compositional and compositional models generally concurred on the direction of cross-sectional and longitudinal relationships (and lack thereof) between PA domains and HRQOL outcomes. …”
Publicado 2023
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435005“…CONCLUSION: SGLT2i can effectively control blood pressure and blood glucose and generally has high safety. For patients with type 2 diabetes mellitus and hypertension with a low risk of genital infection, SGLT2i should be considered as an adjuvant drug for a first-line antihypertensive regimen.…”
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435006What guides back pain care? A content analysis of low back pain directives in the Australian context“…Qualitative content analysis of the directives showed that while there has been increasing attention given to models of care, this is not yet reflected in directives, which generally focus on more specific elements of LBP care at the individual patient and practitioner level. …”
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435007por Kang, Moonil, Ang, Ting Fang Alvin, Devine, Sherral A., Sherva, Richard, Mukherjee, Shubhabrata, Trittschuh, Emily H., Gibbons, Laura E., Scollard, Phoebe, Lee, Michael, Choi, Seo-Eun, Klinedinst, Brandon, Nakano, Connie, Dumitrescu, Logan C., Durant, Alaina, Hohman, Timothy J., Cuccaro, Michael L., Saykin, Andrew J., Kukull, Walter A., Bennett, David A., Wang, Li-San, Mayeux, Richard P., Haines, Jonathan L., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Crane, Paul K., Au, Rhoda, Lunetta, Kathryn L., Mez, Jesse B., Farrer, Lindsay A.“…We analyzed 103,796 longitudinal observations from 23,066 members of community-based (FHS, ACT, and ROSMAP) and clinic-based (ADRCs and ADNI) cohorts using generalized linear mixed models including terms for SNP, age, SNP × age interaction, sex, education, and five ancestry principal components. …”
Publicado 2023
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435008por Gossec, Laure, Siebert, Stefan, Bergmans, Paul, de Vlam, Kurt, Gremese, Elisa, Joven-Ibáñez, Beatríz, Korotaeva, Tatiana V., Lavie, Frederic, Noël, Wim, Nurmohamed, Michael T., Sfikakis, Petros P., Sharaf, Mohamed, Theander, Elke, Smolen, Josef S.“…CONCLUSIONS: At 3 years, improvements in PROs following ustekinumab or TNFi treatment were generally comparable; however, TNFi-treated patients achieved a greater improvement in work productivity, although this group started from a lower baseline. …”
Publicado 2023
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435009por Winternitz, Jamie, Chakarov, Nayden, Rinaud, Tony, Ottensmann, Meinolf, Krüger, Oliver“…While balancing selection is acting on both classes, there is no evidence of differential selection pressure on MHC classes in common buzzards and this result may hold more generally once more data for understudied MHC exons becomes available. …”
Publicado 2023
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435010por Zerdo, Zerihun, Bastiaens, Hilde, Anthierens, Sibyl, Massebo, Fekadu, Masne, Matewos, Biresaw, Gelila, Shewangizaw, Misgun, Tunje, Abayneh, Chisha, Yilma, Yohannes, Tsegaye, Van Geertruyden, Jean-Pierre“…Structured questionnaire was used to collect data on socio-demographic, economic, bed net ownership, bed net utilization, whether the participated child suffered from malaria and has got treatment from a health facility. Generalized mixed effect logistic regression using school as random variable was used to assess the effect of the intervention on the outcome variables. …”
Publicado 2023
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435011“…Multiple regression analysis and generalized additive models were used to examine the association between hs-CRP and BMI. …”
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435012por Leutenegger, Christian M., Lozoya, Cecilia E., Tereski, Jeffrey, Andrews, Jan, Mitchell, Kelly D., Meeks, Cathy, Willcox, Jennifer L., Freeman, Gregory, Richmond, Holly L., Savard, Christian, Evason, Michelle D.“…Elsewhere, PCR has replaced microscopy because of generally increased sensitivity and detection capabilities; however, until recently it has been unavailable commercially. …”
Publicado 2023
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435013por Danneels, Maya, Van Hecke, Ruth, Leyssens, Laura, van de Berg, Raymond, Dhooge, Ingeborg, Cambier, Dirk, Delrue, Stefan, Van Rompaey, Vincent, Maes, Leen“…These motor tasks were also performed in single-task condition. A generalized estimating equations model was used to investigate group differences for all cognitive and motor outcome measures. …”
Publicado 2023
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435014por Neumann, Johannes Tobias, Twerenbold, Raphael, Ojeda, Francisco, Aldous, Sally J., Allen, Brandon R., Apple, Fred S., Babel, Hugo, Christenson, Robert H., Cullen, Louise, Di Carluccio, Eleonora, Doudesis, Dimitrios, Ekelund, Ulf, Giannitsis, Evangelos, Greenslade, Jaimi, Inoue, Kenji, Jernberg, Tomas, Kavsak, Peter, Keller, Till, Lee, Kuan Ken, Lindahl, Bertil, Lorenz, Thiess, Mahler, Simon A., Mills, Nicholas L., Mokhtari, Arash, Parsonage, William, Pickering, John W., Pemberton, Christopher J., Reich, Christoph, Richards, A. Mark, Sandoval, Yader, Than, Martin P., Toprak, Betül, Troughton, Richard W., Worster, Andrew, Zeller, Tanja, Ziegler, Andreas, Blankenberg, Stefan“…In the validation and generalization cohorts, excellent discriminative performance was confirmed, superior to hs-cTn only. …”
Publicado 2023
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435015por Kumar, Jitendra, Coffin, Alisa W., Baffaut, Claire, Ponce-Campos, Guillermo E., Witthaus, Lindsey, Hargrove, William W.“…Constituency of LTAR sites can be used to prioritize the locations of experimental research at or even within particular sites, or to identify the extents that can likely be included when generalizing knowledge across larger regions of the CONUS. …”
Publicado 2023
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435016por Shi, Enxian, Wu, Zhengquan, Karaoglan, Birnur Sinem, Schwenk-Zieger, Sabina, Kranz, Gisela, Abdul Razak, Nilofer, Reichel, Christoph A., Canis, Martin, Baumeister, Philipp, Zeidler, Reinhard, Gires, Olivier“…Sustained hyper-activation of epidermal growth factor receptor (EGFR) induces an invasion-promoting subtype of EMT (EGFR-EMT) characterized by a gene signature (“‘EGFR-EMT_Signature’”) comprising 5´-ectonucleotidase CD73. Generally, CD73 promotes immune evasion via adenosine (ADO) formation and associates with EMT and metastases. …”
Publicado 2023
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435017por Zhu, Xianming, Gebo, Kelly A, Abraham, Alison G, Habtehyimer, Feben, Patel, Eshan U, Laeyendecker, Oliver, Gniadek, Thomas J, Fernandez, Reinaldo E, Baker, Owen R, Ram, Malathi, Cachay, Edward R, Currier, Judith S, Fukuta, Yuriko, Gerber, Jonathan M, Heath, Sonya L, Meisenberg, Barry, Huaman, Moises A, Levine, Adam C, Shenoy, Aarthi, Anjan, Shweta, Blair, Janis E, Cruser, Daniel, Forthal, Donald N, Hammitt, Laura L, Kassaye, Seble, Mosnaim, Giselle S, Patel, Bela, Paxton, James H, Raval, Jay S, Sutcliffe, Catherine G, Abinante, Matthew, Broderick, Patrick, Cluzet, Valerie, Cordisco, Marie Elena, Greenblatt, Benjamin, Petrini, Joann, Rausch, William, Shade, David, Lane, Karen, Gawad, Amy L, Klein, Sabra L, Pekosz, Andrew, Shoham, Shmuel, Casadevall, Arturo, Bloch, Evan M, Hanley, Daniel, Sullivan, David J, Tobian, Aaron A R“…Log(10) cytokine and chemokine concentrations decreased faster among participants in the unvaccinated group than in other groups, but their geometric mean concentrations were generally higher than fully vaccinated participants at 90 days. …”
Publicado 2023
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435018por Mansour, Marthe BL, Busschers, Wim B, Crone, Mathilde R, van Asselt, Kristel M, van Weert, Henk C, Chavannes, Niels H, Meijer, Eline“…Second, ordinal logistic regression was used to assess the baseline characteristics that were associated with user group membership. Finally, generalized estimating equations were used to examine the association between the user groups and smoking status, quitting stage, and self-efficacy over time. …”
Publicado 2023
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435019por Adem, Jibril Bashir, Melaku, Mequannent Sharew, Zeleke, Tirualem, Tesfaye, Muluken, Kitila, Firaol Lemessa, Walle, Agmasie Damtew“…CONCLUSION: This study found that mental healthcare providers at a public referral hospital in Addis Ababa city generally had poor attitudes regarding Tele-psychiatry services. …”
Publicado 2023
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435020por Vanderkarr, Mari F., Ruppenkamp, Jill W., Vanderkarr, Mollie, Holy, Chantal E., Blauth, Michael“…Marginal incremental cost of care associated with non-union and infected non-union and reoperation were estimated using a generalized linear model with log link and gamma distribution. …”
Publicado 2023
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