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  1. 435081
    “…The safety profile was generally consistent with results disclosed previously. …”
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    Abemaciclib plus fulvestrant in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in premenopausal women: subgroup analysis from the MONARCH 2 trial
  2. 435082
    “…Cross-validation between cohorts showed generally a good resemblance between cohorts. Together, our results show that the clustering based on clinical variables readily measured in the clinic (age, HbA(1c), HDL-cholesterol, BMI and C-peptide) results in informative clusters that are representative of the original ANDIS clusters and stable across cohorts. …”
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    Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study
  3. 435083
    “…Both toothpastes were generally well tolerated. CONCLUSION: Three weeks’ twice-daily brushing with the 0.454% w/w stannous fluoride Test toothpaste compared to the Control toothpaste led to statistically significant lower gingival bleeding, gingival inflammation and plaque levels in adults with mild-moderate gingivitis. …”
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    A randomised clinical study investigating efficacy of a stannous fluoride toothpaste in improving gingival health after 3 weeks’ use
  4. 435084
    “…Underreporting bias or validity of self-reported substance use depends on the study population and cannot be generalized to the entire population. This study aimed to compare the validity of self-reported substance use between research setting and primary health care setting from the same source population. …”
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    Validity of self-reported substance use: research setting versus primary health care setting
  5. 435085
    “…CONCLUSIONS: Our approach for estimating population- and spatially-representative PM(2.5) concentrations based on census tract and national grid predictions, respectively, provided generally consistent findings to the original findings using limited monitoring data. …”
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    Reanalysis of the association between reduction in long-term PM(2.5) concentrations and improved life expectancy
  6. 435086
    “…CONCLUSIONS: Although generally positive, Canadian family physicians’ attitudes towards chiropractic are diverse, and most physicians felt that practice diversity among chiropractors was a barrier to interprofessional collaboration. …”
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    Attitudes towards chiropractic: a repeated cross-sectional survey of Canadian family physicians
  7. 435087
    “…Time-varying Cox regression and generalized estimating equation (GEE) analyses were performed. …”
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    Increased radiographic progression of distal hand osteoarthritis occurring during biologic DMARD monotherapy for concomitant rheumatoid arthritis
  8. 435088
    “…Sensitivity analyses were generally consistent with the primary analysis. In placebo-treated patients, no meaningful predictors of Week 52 response were identified. …”
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    Predictors of long-term clinical response in patients with non-radiographic axial spondyloarthritis receiving certolizumab pegol
  9. 435089
    “…The main end point was medication adherence, which was defined as participant compliance in taking all 4 cardioprotective medications that would improve the patient’s outcome (therapies included antiplatelet therapy, β-blockers, statins, and angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers). Multivariable generalized estimating equations were used to compare the primary and secondary outcomes between the 2 groups and to calculate the relative risk (RR) at 12 months. …”
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    The Effect of a WeChat-Based Tertiary A-Level Hospital Intervention on Medication Adherence and Risk Factor Control in Patients With Stable Coronary Artery Disease: Multicenter Prospective Study
  10. 435090
    “…The pattern of results assessing construct validity was acceptable for the PICQ Coping and Impact scores, with the magnitude of correlations and effect sizes generally meeting a priori expectations. The corresponding GRS effect sizes for the PICQ Coping scores were −1.23 (i.e., large) for Patient Global Impression of Change (PGIC) and −0.72 (i.e., medium) for uncorrected near visual acuity (UNVA). …”
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    Development of the Presbyopia Impact and Coping Questionnaire
  11. 435091
    “…La majorité des effets indésirables étaient d’intensité légère à modérée et disparaissaient généralement quelques jours après la vaccination. Par rapport à la première dose, les effets indésirables signalés après la deuxième dose étaient plus légers et moins fréquents. …”
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    Effets secondaires cutanés du vaccin anti-SARS-CoV2. Expérience chez le personnel soignant du CHU Hassan 2 de Fès
  12. 435092
    “…Health-related quality of life (HRQoL) 36-item Short Form Health Survey questionnaire scores for those later prescribed rhPTH(1-84) were generally lower than those for patients in the conventional therapy cohort. …”
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    The PARADIGHM (physicians advancing disease knowledge in hypoparathyroidism) registry for patients with chronic hypoparathyroidism: study protocol and interim baseline patient characteristics
  13. 435093
    “…Patient respondents were generally well educated, most found the history (259/321, 80.7%) and agenda (286/321, 89.1%) questions not difficult to answer; more than 92.2% (296/321) thought sending answers before the visit a good idea; 68.8% (221/321) thought the questions helped them prepare for the visit. …”
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    Patients Contributing to Visit Notes: Mixed Methods Evaluation of OurNotes
  14. 435094
    “…Those who decided to test spent an average of 10 (SD 2.57) minutes on the chat, selected an average of 1.87 (SD 1.2) additional pieces of information, and generally did not ask open-ended questions. Those who were unsure spent 4 more minutes on average (mean 14.1, SD 7.41; P=.03) on the chat, selected an average of 3.67 (SD 2.9) additional pieces of information, and asked at least one open-ended question. …”
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    Patient Interactions With an Automated Conversational Agent Delivering Pretest Genetics Education: Descriptive Study
  15. 435095
    “…As such, this intervention approach may hold promise as a population health behavior change strategy within schools and may have implications for the use of online food-ordering systems more generally; however, more research is required. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry ACTRN12618000855224; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?…”
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    Long-term Effectiveness of a Multistrategy Behavioral Intervention to Increase the Nutritional Quality of Primary School Students’ Online Lunch Orders: 18-Month Follow-up of the Click & Crunch Cluster Randomized Controlled Trial
  16. 435096
    “…Circulating protein concentrations were not correlated with in vitro gene-expression, but circulating P-selectin was generally elevated in AF and FU patients compared to non-AF patients. …”
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    Anti-inflammatory HDL effects are impaired in atrial fibrillation
  17. 435097
    “…CONCLUSION: In the light of this work, the repercussions of this crisis, during the first wave, were generally well experienced by our patients, in the psychiatric environment, with a good awareness of the stakes and the risks incurred but also with a glimmer of hope for a resolution of the situation soon. …”
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    Regards croisés de patients psychiatriques COVID positifs ou négatifs sur leur vécu de la crise sanitaire au sein d’une unité COVID lors de la première vague
  18. 435098
    “…CONCLUSION: Individuals with HCV in Pakistan generally report threatening or negative views about HCV infection. …”
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    Illness perception about hepatitis C virus infection: a cross-sectional study from Khyber Pakhtunkhwa Pakistan
  19. 435099
    “…Quantitative real-time PCR further revealed that TaSPP-5Aa showed relatively higher expression than TaSPP-5Ab in wheat seedling leaves, generally associating with increased sucrose content and TGW. …”
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    Characterization of TaSPP-5A gene associated with sucrose content in wheat (Triticum aestivum L.)
  20. 435100
    “…Logistic regression and Generalized Linear Mixed Models were employed to test hypotheses between a multimorbidity resilience index and its three sub-indices measured using pre-pandemic Follow-up 1 data and the outcomes, including covariates. …”
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    Multimorbidity resilience and COVID-19 pandemic self-reported impact and worry among older adults: a study based on the Canadian Longitudinal Study on Aging (CLSA)
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