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  1. 435261
    “…[Figure: see text] [Figure: see text] CONCLUSION: ATM-AVI (± MTZ) was effective in treating patients with cIAI and HAP/VAP, displaying similar efficacy to MER ± COL. ATM-AVI was generally well tolerated. These data support potential use of ATM-AVI for the treatment of serious infections caused by susceptible Gram-negative bacteria. …”
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    2893 A. Efficacy and Safety of Aztreonam-Avibactam for the Treatment of Serious Infections Due to Gram-Negative Bacteria, Including Metallo-β-Lactamase-Producing Pathogens: Phase 3 REVISIT Study
  2. 435262
    “…[Figure: see text] [Figure: see text] [Figure: see text] CONCLUSION: IPD, ACP, and AOM IRs disease burden remains substantial with a disproportionately high impact of the most severe disease manifestations (IPD and inpatient ACP) among infants in the first year of life, despite marked declines following the introduction of PCV13. Disease IRs were generally higher in Medicaid children, particularly at the start of the study period, but also declined more significantly over time compared to IRs in CCAE children. …”
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    1693. Incidence of Pneumococcal Disease in Children ≤48 Months Old in the United States: 2010-2019
  3. 435263
    “…[Figure: see text] [Figure: see text] [Figure: see text] CONCLUSION: Sotrovimab 500 mg IM injection had a favorable safety profile and was generally well tolerated at all injection sites, and at volumes of up to 5 mL at DG and AL thigh sites, and one 2.5 mL injection into each deltoid muscle. …”
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    517. Safety and Tolerability of Intramuscular (IM) Sotrovimab 500 mg Administered at Different Injection Sites: Results from the Phase I COSMIC Study
  4. 435264
    “…To account for multiple VL measures per patient, a Generalized Estimating Equation logistic regression estimated odds ratios (OR) and a 95% confidence interval. …”
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    1577. HIV Viral Load Suppression in Patients Utilizing an Integrated Health System Specialty Pharmacy Compared to a Non-integrated Specialty Pharmacy Model
  5. 435265
    “…[Figure: see text] [Figure: see text] CONCLUSION: We observed few cardiovascular complications among YES C3 participants who generally experienced mild infection, with most enrolled in the pre-vaccine and pre-Omicron era. …”
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    477. Characteristics and Long-Term Outcomes of Cardiac Complications of SARS-CoV-2 in Youth: Results from the EPICC YES C3 Prospective Longitudinal Cohort Module
  6. 435266
    “…We examined the association between census tract-level SVI (in quartiles) and the risk of infection among household contacts using Poisson regression with generalized estimating equations, accounting for household clustering. …”
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    2293. Examining social vulnerability and its effect on COVID-19 transmission in households
  7. 435267
    “…Demographics and baseline characteristics were generally comparable for both treatment groups in the MITT population, with the exception of preexisting cerebrovascular conditions which were higher in IMI/REL vs PIP/TAZ group. …”
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    2519. A Multi-national Phase 3, Randomized, Double-Blind, Active Comparator-Controlled Clinical Trial to Study the Safety, Tolerability, and Efficacy of Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Subjects with Hospital-Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia
  8. 435268
    “…Interestingly, ADCC was generally higher in newborn cord blood compared to maternal peripheral blood by 2.5-fold in both groups, while ADCP and opsonization was not. …”
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    467. Maternal Antibody and Placental Transfer Increases with Hybrid Immunity Against SARS-CoV-2 but Transferred Antibody is Qualitatively Different
  9. 435269
    “…All participants received the intervention. We used generalized estimating equations (GEEs) clustered by participant to evaluate changes in scores from baseline to follow-up, and correlates of participant WhatsApp messaging. …”
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    Facilitated WhatsApp Support Groups for Youth Living With HIV in Nairobi, Kenya: Single-Arm Pilot Intervention Study
  10. 435270
    por Last, William M, Ginn, Fawn M
    Publicado 2005
    “…With such a vast array of compositions, it is difficult to generalize. Nonetheless, the paucity of Cl-rich lakes makes the northern Great Plains basins somewhat unusual compared with salt lakes in many other areas of the world (e.g., Australia, western United States). …”
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    Saline systems of the Great Plains of western Canada: an overview of the limnogeology and paleolimnology
  11. 435271
    “…Finally, in comparing Brazilian prices for locally produced generic ARVs to the lowest international prices meeting global pharmaceutical quality standards, we find that current prices for Brazil's locally produced generics are generally much higher than corresponding global prices, and note that these prices have risen in Brazil while declining globally. …”
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    Evolution of Antiretroviral Drug Costs in Brazil in the Context of Free and Universal Access to AIDS Treatment
  12. 435272
    por Amoss, Harold Lindsay
    Publicado 1913
    “…Of course this does not mean that carbon dioxide prevents the action of the oxidizing ferments generally. In this particular case the substance to be oxidized, namely phenolphthalin, was not allowed by reason of the presence of the carbon dioxide to combine with the alkali and thereby assume a state in which it could be easily oxidized. …”
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    ORGANIC MATTER IN THE EXPIRED BREATH WITH ESPECIAL REFERENCE TO ITS INHIBITING POWER ON OXIDIZING FERMENTS
  13. 435273
    “…Hence we believe that this disease is found generally prevalent in this part of the country. We have demonstrated that practically all rabbits with intermittent or chronic snuffles reveal old chronic inflammatory processes of the upper nasal passages associated with thick inspissated pus in one or more sinuses. …”
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    STUDIES ON THE ETIOLOGY OF SNUFFLES IN STOCK RABBITS : PARANASAL SINUSITIS A FACTOR IN THE INTERPRETATION OF EXPERIMENTAL RESULTS.
  14. 435274
    por Carrel, Alexis
    Publicado 1926
    “…But this rarely happens. Generally when the medium contained only one fragment of spleen or leucocytic film, or 1 drop of embryonic pulp, the virus disappeared rapidly. …”
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    SOME CONDITIONS OF THE REPRODUCTION IN VITRO OF THE ROUS VIRUS
  15. 435275
    por Olitsky, Peter K.
    Publicado 1939
    “…The significance of the second major lesion in the central nervous system, namely, the generally marked perivascular reaction, is also still to be determined. …”
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    EXPERIMENTAL STUDIES OF THE VIRUS OF INFECTIOUS AVIAN ENCEPHALOMYELITIS
  16. 435276
    por Pillemer, L., Seifter, S., Ecker, E. E.
    Publicado 1942
    “…Mid-piece, which contains C'1, generally stated to be the single combining component of complement, is adsorbed by immune aggregates in varying amounts depending on the experimental conditions employed. 5. …”
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    THE RÔLE OF THE COMPONENTS OF COMPLEMENT IN SPECIFIC IMMUNE FIXATION
  17. 435277
    “…These discoveries have placed histocompatibility gene products on a more complex level of biologic function than was heretofore generally considered (15). Thus, the hypothesis was made from these observations that genes in the H-2 complex coded for products involved in the development of effective cell-cell interactions in the immune response (8, 9, 15). …”
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    ACTIVATION OF T AND B LYMPHOCYTES IN VITRO : III. Presence of Ia Determinants on Allogeneic Effect Factor
  18. 435278
    por Loeb, Jacques
    Publicado 1923
    “…The cataphoretic P.D. of suspended particles is assumed to be due to an excess in the concentration of one kind of a pair of oppositely charged ions in the film of water enveloping the particles and this excess is generally ascribed to a preferential adsorption of this kind of ions by the particle. …”
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    ON THE LOCATION OF THE FORCES WHICH DETERMINE THE ELECTRICAL DOUBLE LAYER BETWEEN COLLODION PARTICLES AND WATER
  19. 435279
    por Ponder, Eric
    Publicado 1945
    “…Δ is a non-linear function of Q and of c (1), the initial quantity of lysin present in the hemolytic system, Δ generally increasing as c (1) increases. 6. The inhibitory effect of cholesterol sols is essentially due to a reaction between the cholesterol and the lysin in the bulk phase of the system, modified by what appear to be redistribution effects which depend on the kind and number of red cells added to complete the hemolytic system. 7. …”
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    THE MECHANISM OF THE INHIBITION OF HEMOLYSIS : IV. THE TYPES OF REACTION INVOLVED
  20. 435280
    “…At those levels the firing threshold of the cell for orthodromic discharges is generally reached. 2. The safety factor for conduction between axon and cell soma is reduced under three unrelated conditions, (a) During the recovery period (2 to 3 msec.) immediately following an impulse which has conducted fully over the cell soma, a second impulse may be delayed, may invade the soma partially, or may be blocked completely. …”
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    FURTHER STUDY OF SOMA, DENDRITE, AND AXON EXCITATION IN SINGLE NEURONS
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