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  1. 435681
    “…Baseline characteristics, including causative pathogens, were generally similar in participants with R-SOFA ≥ 2 or CV-SOFA ≥ 2 across treatment arms. …”
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    Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: a subset analysis of the phase 3, randomized, controlled ASPECT-NP trial
  2. 435682
    “…The percentage of vixarelimab recipients reporting any TEAE was 91.3% (21/23) versus 76.9% (20/26) of placebo recipients; drug-related TEAEs generally were similar between the two groups (vixarelimab, 43.5% [10/23]; placebo, 38.5% [10/26]). …”
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    Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a study
  3. 435683
    por Gendron, Nicolas
    Publicado 2023
    “…La VITT présente de fortes similitudes avec la TIH mais les patients atteints de VITT n’ont généralement pas reçu d’héparine. Les patients atteints de VITT ne présentaient aucun facteur de risque médical identifiable, notamment une thrombophilie et/ou des antécédents de thrombose. …”
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    Quelles leçons avons-nous tiré des thromboses post vaccin anti-COVID-19
  4. 435684
    “…INTRODUCTION: L’étude de l'efficacité vaccinale d'une part, et des conséquences médicales du COVID-19 d'autre part, nécessitent généralement la mise en place de deux designs spécifiques. …”
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    Design cas témoins apparié sur score de risque : un outil méthodologique original pour une étude de l'efficacité vaccinale et des conséquences médicales de l'hospitalisation pour COVID-19 en France.
  5. 435685
    “…Cluster randomised controlled trials meeting these study criteria were included: generally healthy school students aged 4-18 years; intervention with ≥1 nutritional components in a school setting; and studies that assessed anthropometric measures (eg, body mass index, body fat) or measures related to the quality of diet (eg, intake of fruit and vegetables), or both. …”
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    Effects of nutritional intervention strategies in the primary prevention of overweight and obesity in school settings: systematic review and network meta-analysis
  6. 435686
    “…Macroscopically, these tumors generally have a round shape and clear boundary. They present with variegated, grayish yellow and grayish brown cut surface. …”
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    TFEB Rearranged Renal Cell Carcinoma: Pathological and Molecular Characterization of 10 Cases, with Novel Clinical Implications: A Single Center 10-Year Experience
  7. 435687
    “…The distribution of genotypes of polymorphic bPRL and bNOS2 generally coincides, and bPRL-RsaI(BB) is the most common genotype. …”
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    Genetic polymorphism of prolactin and nitric oxide synthase in Holstein cattle
  8. 435688
    “…Although previous research showed that computer-aided diagnosis (CAD) systems have great potential in H. pylori infection diagnosis, their generalization and explainability are still a challenge. …”
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    An explainable artificial intelligence system for diagnosing Helicobacter Pylori infection under endoscopy: a case–control study
  9. 435689
    “…We further explored the relationships of significant CD-related BAs and DF via Generalized Estimation Equations. Finally, we used a tree-based machine-learning algorithm (XGBoost) with 5-fold cross-validation to assess the prediction performance of CD onset using BA from all sources as well as DF. …”
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    A238 BILE ACID COMPOSITION AND DIETARY FAT: IMPLICATIONS FOR CROHN’S DISEASE IN A COHORT OF HEALTHY FIRST-DEGREE RELATIVES
  10. 435690
    “…However, this conclusion must be interpreted with caution because of the generally unsatisfactory study quality and inconsistent conclusions of the included SRs/MAs. …”
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    Effectiveness and safety of manual therapy for knee osteoarthritis: An overview of systematic reviews and meta-analyses
  11. 435691
    “…For maximum temperature, a significant (p < 0.05) curvilinear association was observed with sleep (half-U) and physical activity (inverted-U), where the decrease in sleep duration appeared to slow around 23 °C, LPA peaked at 31 oC and MVPA at 27 °C. CONCLUSIONS: Generally, adults tended to be less active and more sedentary during extremes of weather and sleep less as temperatures rise. …”
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    Weather associations with physical activity, sedentary behaviour and sleep patterns of Australian adults: a longitudinal study with implications for climate change
  12. 435692
    por Anmella, Gerard, Sanabra, Miriam, Primé-Tous, Mireia, Segú, Xavier, Cavero, Myriam, Morilla, Ivette, Grande, Iria, Ruiz, Victoria, Mas, Ariadna, Martín-Villalba, Inés, Caballo, Alejandro, Esteva, Julia-Parisad, Rodríguez-Rey, Arturo, Piazza, Flavia, Valdesoiro, Francisco José, Rodriguez-Torrella, Claudia, Espinosa, Marta, Virgili, Giulia, Sorroche, Carlota, Ruiz, Alicia, Solanes, Aleix, Radua, Joaquim, Also, María Antonieta, Sant, Elisenda, Murgui, Sandra, Sans-Corrales, Mireia, H Young, Allan, Vicens, Victor, Blanch, Jordi, Caballeria, Elsa, López-Pelayo, Hugo, López, Clara, Olivé, Victoria, Pujol, Laura, Quesada, Sebastiana, Solé, Brisa, Torrent, Carla, Martínez-Aran, Anabel, Guarch, Joana, Navinés, Ricard, Murru, Andrea, Fico, Giovanna, de Prisco, Michele, Oliva, Vicenzo, Amoretti, Silvia, Pio-Carrino, Casimiro, Fernández-Canseco, María, Villegas, Marta, Vieta, Eduard, Hidalgo-Mazzei, Diego
    Publicado 2023
    “…Self-assessments for anxiety (Generalized Anxiety Disorder 7-item) and depression (Patient Health Questionnaire-9) symptoms and work-related burnout (based on the Maslach Burnout Inventory) were administered at baseline and every 2 weeks. …”
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    Vickybot, a Chatbot for Anxiety-Depressive Symptoms and Work-Related Burnout in Primary Care and Health Care Professionals: Development, Feasibility, and Potential Effectiveness Studies
  13. 435693
    “…Loneliness was measured using the 3-item UCLA Loneliness Scale. Weighted generalized estimating equations estimated the prevalence of loneliness pre-pandemic and during the pandemic. …”
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    Increased prevalence of loneliness and associated risk factors during the COVID-19 pandemic: findings from the Canadian Longitudinal Study on Aging (CLSA)
  14. 435694
    “…BACKGROUND: The US Food and Drug Administration (FDA) interchangeability guidelines state that the primary endpoint in a switching study should assess the impact of switching between the proposed interchangeable product and the reference product on clinical pharmacokinetics (PK) and pharmacodynamics (if available), as these assessments are generally sensitive to changes in immunogenicity and/or exposure that may arise due to switching. …”
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    Assessing the Interchangeability of AVT02 and Humira(®) in Participants with Moderate‑to‑Severe Chronic Plaque Psoriasis: Pharmacokinetics, Efficacy, Safety, and Immunogenicity Results from a Multicenter, Double-Blind, Randomized, Parallel-Group Study
  15. 435695
    “…Blood samples were collected in the early morning after the overnight fasting and were analyzed using an automated electrochemiluminescence immunoassay on the LABOSPECT 008AS platform (Hitachi Hi-Tech Co., Ltd., Tokyo, Japan). The generalized additive model was further applied for nonlinear associations. …”
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    Association of 25-hydroxyvitamin D levels with lipid profiles in osteoporosis patients: a retrospective cross-sectional study
  16. 435696
    “…Perceived adverse events reported by spray operators and householders were generally very low (< 6%) in both study arms. VECTRON™ T500 was non-inferior to Fludora® Fusion in reducing the risk of malaria transmission by pyrethroid resistant vectors when applied for IRS in communities in central Benin. …”
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    Community evaluation of VECTRON™ T500, a broflanilide insecticide, for indoor residual spraying for malaria vector control in central Benin; a two arm non-inferiority cluster randomised trial
  17. 435697
    “…To estimate the difference in risk (with 95% CI), between the treatment and control arms, binary regression (a generalized linear multivariable model with an identity link function and binomial distribution) will be used. …”
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    Intratracheal budesonide mixed with surfactant to increase survival free of bronchopulmonary dysplasia in extremely preterm infants: statistical analysis plan for the international, multicenter, randomized PLUSS trial
  18. 435698
    “…BACKGROUND: Daily and event-driven HIV pre-exposure prophylaxis (PrEP) with oral tenofovir-emtricitabine is highly effective to prevent HIV in men who have sex with men (MSM). PrEP care generally consists of in-clinic monitoring every 3 months that includes PrEP dispensing, counseling, and screening for HIV and sexually transmitted infections (STIs). …”
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    Online-Mediated HIV Pre-exposure Prophylaxis Care and Reduced Monitoring Frequency for Men Who Have Sex With Men: Protocol for a Randomized Controlled Noninferiority Trial (EZI-PrEP Study)
  19. 435699
    “…CONCLUSIONS: Nearly three decades into Namibia’s generalized HIV epidemic, these are the first estimates of HIV incidence for its highest prevalence region. …”
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    Rates and Correlates of HIV Incidence in Namibia’s Zambezi Region From 2014 to 2016: Sentinel, Community-Based Cohort Study
  20. 435700
    “…At the end of each intervention, clinical outcomes and self-reported outcomes were collected to compare with their baseline performance. A generalized linear model ANOVA was used to compare the performance of each intervention with respect to their own baseline. …”
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    Using a microprocessor knee (C-Leg) with appropriate foot transitioned individuals with dysvascular transfemoral amputations to higher performance levels: a longitudinal randomized clinical trial
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