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435921por Kaynar, A. Murat, Lin, Charles, Sanchez, Andrea Gomez, Lavage, Danielle R., Monroe, Amy, Zharichenko, Nicole, Strassburger, Meredith, Saucier, Katheryn, Groff, Yram J., Klatt, Brian A., O’Malley, Michael J., Szigethy, Eva, Wasan, Ajay D., Chelly, Jacques E.“…The primary outcome will be day of surgery anxiety or depression symptoms measured with the PROMIS Short Form v1.0 -Anxiety 4a/Depression and Generalized Anxiety Disorder Measure (GAD-7) and Patient Health Questionnaire (PHQ-8). …”
Publicado 2023
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435922por Dyson, Alftan, Aberg, Judith A, Molina, Jean-Michel, Cassetti, Isabel, Kozal, Michael, Treviño-Pérez, Sandra, Latiff, Gulam, Lalezari, Jacob, Pialoux, Gilles, Li, Bo, Prakash, Manyu, Clark, Andrew, Tenorio, Allan R, Pierce, Amy, Lataillade, Max“…Virologic response rates were generally comparable among subgroups and consistent with overall response rate (Table 1). …”
Publicado 2023
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435923por Snape, Matthew D, Ghamloush, Sabine Schnyder, Chen, Grace L, Dhar, Rakesh, Mithani, Runa, Righi, Vinicius, Morsy, Louie, Kapoor, Archana, Girard, Bethany, Asmar, Laila El, Shaw, Christine A“…In both trials, bAb responses were generally preF biased. [Figure: see text] [Figure: see text] CONCLUSION: In seropositive children aged 12-59 months, mRNA-1345 and mRNA-1653 were well-tolerated and boosted RSV and hMPV plus PIV3 antibodies, respectively, supporting their continued development and that of a combination RSV and hMPV vaccine. …”
Publicado 2023
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435924por Panther, Lori, Basnet, Sandeep, Fierro, Carlos, Brune, Daniel, Leggett, Richard, Peterson, James, Pickrell, Paul, Lin, Jiang, Wu, Kai, Lee, Heather, Hasselbeck, Roxane, Natenshon, Andrew, Miller, Jacqueline“…CONCLUSION: mRNA-1647 was generally safe and well-tolerated and induced antigen-specific immune responses at all dose levels in both CMV-seronegative and -seropositive participants. …”
Publicado 2023
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435925por Mellis, Alexandra, Smith-Jeffcoat, Sarah E, Petrie, Joshua, Keipp Talbot, H, Morrissey, Kerry Grace, Stockwell, Melissa, Maldonado, Yvonne A, Bowman, Natalie M, Lutrick, Karen, Rao, Suchitra, Salvatore, Phillip P, Biddle, Jessica E, Olivo, Vanessa, Battan-Wraith, Steph, Merrill, Lori S, McLaren, Son H, Sano, Ellen, Diaz, Anny, Sarnquist, Clea, Govindaranjan, Prasanthi, Goodman, Sara H, Ellingson, Katherine, Ledezma, Karla I, Pryor, Kathleen, Lin, Jessica T, Bullock, Ayla, Yang, Amy, Belongia, Edward, McLean, Huong, Asturias, Edwin J, Izurieta, Hector, Hart, Kimberly W, Schmitz, Jonathan, Zhu, Yuwei, Rolfes, Melissa A, Grijalva, Carlos G“…Risk of secondary infection (any PCR positivity) among eligible, tested HHC (Methods 1) by symptoms of primary cases was estimated using Poisson regression with generalized estimating equations. We estimated days from onset to last PCR positive in a survival model. …”
Publicado 2023
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435926por Balachandran, Neha, Wikswo, Mary, Boom, Julie A, Sahni, Leila C, Selvarangan, Rangaraj, Harrison, Christopher J, Halasa, Natasha B, Stewart, Laura S, Weinberg, Geoffrey A, Szilagyi, Peter G, Englund, Janet A, Klein, Eileen J, Staat, Mary A, Burrell, Allison, Williams, John V, Michaels, Marian G, Parashar, Umesh D, Mirza, Sara“…Acute gastroenteritis (AGE) often requires medical attention but is generally managed conservatively. We describe antibiotic use among children with AGE in two healthcare settings. …”
Publicado 2023
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435927por Dearnaley, D P, Hall, E, Lawrence, D, Huddart, R A, Eeles, R, Nutting, C M, Gadd, J, Warrington, A, Bidmead, M, Horwich, A“…Acute side effects were generally mild and 18 weeks after treatment, only four and five of the 126 men had persistent ⩾Grade 1 bowel or bladder side effects, respectively. …”
Publicado 2005
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435928“…Implementing such model is feasible and decision to generalize it was made in Québec. 2. POPULATION IMPACT OF PRISMA ON FRAIL OLDER PEOPLE AND UTILIZATION OF HEALTH AND SOCIAL SERVICES: Hébert R, Raîche M, Dubois M-F, Gueye NR, Dubuc N, Tousignant M Objective: The objective of the population impact study was to evaluate the impact of the PRISMA model on health, satisfaction and services utilization of frail older people. …”
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435929por van den Heever, Alex M“…After a two-year lag, dramatically reduced cost trends and contributions became evident. Aside from generally tighter regulation across a range of fronts, this appears related to the need for schemes to compete more on the basis of healthcare provider costs than demographic risk profiles. …”
Publicado 2012
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435930“…Adverse events were described as mild for all evaluated drugs, but adverse event monitoring and reporting was generally of low quality. AUTHORS' CONCLUSIONS: Praziquantel 40 mg/kg is the most studied drug for treating urinary schistosomiasis, and has the strongest evidence base. …”
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435931por Widyastuti, Maria Digna Winda, Bardosh, Kevin Louis, Sunandar, ᅟ, Basri, C., Basuno, E., Jatikusumah, A., Arief, R. A., Putra, A. A. G., Rukmantara, A., Estoepangestie, A. T. S., Willyanto, I., Natakesuma, I. K. G., Sumantra, I. P., Grace, D., Unger, F., Gilbert, J.“…The level of community knowledge about rabies and its associated control programs were generally fair and community attitudes were positive. …”
Publicado 2015
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435932por Kirkegaard, K., Sundvall, L., Erlandsen, M., Hindkjær, J.J., Knudsen, U.B., Ingerslev, H.J.“…LIMITATIONS, REASONS FOR CAUTION: Only good prognosis patients were enrolled, so these results may not be generalized to all infertile women. Not all patient-related factors were investigated. …”
Publicado 2016
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435933por Niculescu, A B, Levey, D F, Phalen, P L, Le-Niculescu, H, Dainton, H D, Jain, N, Belanger, E, James, A, George, S, Weber, H, Graham, D L, Schweitzer, R, Ladd, T B, Learman, R, Niculescu, E M, Vanipenta, N P, Khan, F N, Mullen, J, Shankar, G, Cook, S, Humbert, C, Ballew, A, Yard, M, Gelbart, T, Shekhar, A, Schork, N J, Kurian, S M, Sandusky, G E, Salomon, D R“…We have previously provided proof of principle for the use of blood gene expression biomarkers to predict future hospitalizations due to suicidality, in male bipolar disorder participants. We now generalize the discovery, prioritization, validation, and testing of such markers across major psychiatric disorders (bipolar disorder, major depressive disorder, schizoaffective disorder, and schizophrenia) in male participants, to understand commonalities and differences. …”
Publicado 2015
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435934por Lipnicki, Darren M., Crawford, John D., Dutta, Rajib, Thalamuthu, Anbupalam, Kochan, Nicole A., Andrews, Gavin, Lima-Costa, M. Fernanda, Castro-Costa, Erico, Brayne, Carol, Matthews, Fiona E., Stephan, Blossom C. M., Lipton, Richard B., Katz, Mindy J., Ritchie, Karen, Scali, Jacqueline, Ancelin, Marie-Laure, Scarmeas, Nikolaos, Yannakoulia, Mary, Dardiotis, Efthimios, Lam, Linda C. W., Wong, Candy H. Y., Fung, Ada W. T., Guaita, Antonio, Vaccaro, Roberta, Davin, Annalisa, Kim, Ki Woong, Han, Ji Won, Kim, Tae Hui, Anstey, Kaarin J., Cherbuin, Nicolas, Butterworth, Peter, Scazufca, Marcia, Kumagai, Shuzo, Chen, Sanmei, Narazaki, Kenji, Ng, Tze Pin, Gao, Qi, Reppermund, Simone, Brodaty, Henry, Lobo, Antonio, Lopez-Anton, Raúl, Santabárbara, Javier, Sachdev, Perminder S.“…We used only one test to represent cognitive domains, and though a prototypical one, we nevertheless urge caution in generalizing the results to domains rather than viewing them as test-specific associations. …”
Publicado 2017
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435935por Monge, Cecilia, Maeng, Hoyoung, Brofferio, Alessandra, Apolo, Andrea B., Sathya, Bharath, Arai, Andrew E., Gulley, James L., Bilusic, Marijo“…The most commonly observed ECG changes are generalized repolarization abnormalities, prolonged QT interval, and conduction abnormalities (2). …”
Publicado 2018
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435936“…Colchicine is cheap and generally well tolerated at lower doses. Colchicine is first line therapy for recurrent pericarditis. …”
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435937por Eckardt, Patricia, Kovner, Christine, Hammer, Marilyn, Barton-Burke, Margaret, McCabe, Margaret, Cohn, Elizabeth, Marino, Marie, Behrens, Liza“…Expected outcomes are an effective pilot educational intervention for practicing nurses and students and valid and reliable evaluation tools and plan that can be generalized to the larger CRN and nursing community. …”
Publicado 2018
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435938por Todd, Ewen C. D.“…Where the causative agents are known, the kinds of pathogens are generally similar to those found in the West, e.g., Salmonella, but many outbreaks seem to have short incubation periods that point to a toxin of some kind of chemical or biological origin, but these are almost never identified. …”
Publicado 2016
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435939por Sutter, F., Borchardt, S., Schuenemann, G.M., Rauch, E., Erhard, M., Heuwieser, W.“…To evaluate the effect of 2 different treatment procedures, a generalized linear mixed model was constructed using SPSS (SPSS Inc., IBM, Ehningen, Germany). …”
Publicado 2019
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435940por Osl, Theresa, Schmidt, Alexander, Schwaiger, Markus, Schottelius, Margret, Wester, Hans-Jürgen“…Conclusions: The in-depth evaluation of a series of novel CPCR4- and iodoCPCR4 analogs with modified linker structure has yielded reliable structure-activity relationships. It was generally observed that a) AMBA-by-ABA-substitution leads to enhanced ligand internalization, b) the extension of the ABA-linker by two additional amino acids (DOTA-Xaa(2)-Xaa(1)-ABA-) provides sufficient linker length to minimize the interaction of the [M(3+)]DOTA-chelate with the receptor, and that c) introduction of a cationic side chain (Xaa(2)) greatly enhances receptor affinity of the constructs, obliterating the necessity for Tyr(1)-iodination of the pentapeptide core to maintain high receptor affinity (such as in [(177)Lu]PentixaTher). …”
Publicado 2020
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