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  1. 2001
    “…The myriad of presentations associated with PHP are well established, however gout is not commonly associated with this disease. …”
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    MON-376 Head to Toe Hyperparathyroidism - Impending Hyperparathyroid Crisis and Subsequent Crystal Arthropathies
  2. 2002
    “…Safety outcomes included new onset or worsening of diabetes mellitus (DM), muscular disorders, gout and worsening of renal function. RESULTS: Six RCTs with a total of 3956 patients and follow-ups of four to 52 weeks were identified. …”
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    Clinical efficacy and safety outcomes of bempedoic acid for LDL-C lowering therapy in patients at high cardiovascular risk: a systematic review and meta-analysis
  3. 2003
    por Cowley, Sharon, McCarthy, Geraldine
    Publicado 2023
    “…Treatment is also problematic as unlike gout, there are no agents available that decrease the crystal burden. …”
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    Diagnosis and Treatment of Calcium Pyrophosphate Deposition (CPPD) Disease: A Review
  4. 2004
    “…Similar to CVDs, gout attacks occur more frequently in the morning and at night. …”
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    Diurnal Variations in Serum Uric Acid, Xanthine, and Xanthine Oxidoreductase Activity in Male Patients with Coronary Artery Disease
  5. 2005
    por Bray, George A.
    Publicado 2013
    “…By worsening blood lipids, contributing to obesity, diabetes, fatty liver, and gout, fructose in the amounts currently consumed is hazardous to the health of some people.…”
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    Energy and Fructose From Beverages Sweetened With Sugar or High-Fructose Corn Syrup Pose a Health Risk for Some People(1)(2)
  6. 2006
    “…OBJECTIVE: To assess the value of MicroPure, a new ultrasound image processing technique, in identifying microcalcifications (formed by monosodium urate crystals) in the first metatarsophalangeal joints attacked by gout compared to gray-scale ultrasound images. MATERIALS AND METHODS: Thirty-six patients who fulfilled the study inclusion criteria underwent gray-scale ultrasound and MicroPure examinations of the first metatarsophalangeal joints attacked by gout. …”
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    MicroPure Imaging for the Evaluation of Microcalcifications in Gouty Arthritis Involving the First Metatarsophalangeal Joint: A Preliminary Study
  7. 2007
    “…More patients in the hyperuricaemic group achieved a serum uric acid level of <360 µmol/l (∼6 mg/dl) with both canagliflozin 100 mg (23.5%) and 300 mg (32.4%) compared with placebo (3.1%). Incidences of gout and kidney stones were low and similar across groups. …”
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    Effect of canagliflozin on serum uric acid in patients with type 2 diabetes mellitus
  8. 2008
    por Poh, Xue Er, Lee, Chien-Te, Pei, Sung-Nan
    Publicado 2017
    “…INTRODUCTION: Febuxostat, a nonpurine xanthine oxidase inhibitor, is approved as the first-line urate-lowering therapy in gout patients with normal renal function or mild to moderate renal impairment. …”
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    Febuxostat-induced agranulocytosis in an end-stage renal disease patient: A case report
  9. 2009
    por Mendes, Tiago Manuel
    Publicado 2018
    “…CASE DESCRIPTION: An 86-year-old man with a history of gout and glaucoma, presented to the emergency department with progressive confusion, dizziness, disequilibrium and slurred speech, 3 days after he had started acetazolamide following ocular surgery. …”
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    Stroke Mimic Caused by Acetazolamide
  10. 2010
    “…Mutations in this transporter cause gout and these mutations occur at significant prevalence in general population. …”
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    Pharmacologic inducers of the uric acid exporter ABCG2 as potential drugs for treatment of gouty arthritis
  11. 2011
    “…Ophthalmological examination in two adult brothers affected with hyperuricemia, gout, and CKD revealed the presence of optic disc pits, consistent with optic nerve coloboma, thereby revising the diagnosis from FJHN to RCS. …”
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    Whole genome sequence analysis identifies a PAX2 mutation to establish a correct diagnosis for a syndromic form of hyperuricemia
  12. 2012
    “…Through Mendelian Randomization analysis, we discover 51 causal relationships, including previously known agonistic effects of urate on gout and cystatin C on stroke. Finally, we develop polygenic risk scores for each biomarker and built ‘multi-PRS’ models for diseases using 35 PRSs simultaneously, which improved chronic kidney disease, type 2 diabetes, gout, and alcoholic cirrhosis genetic risk stratification in an independent dataset (FinnGen; n=135,500) relative to single-disease PRSs. …”
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    Genetics of 35 blood and urine biomarkers in the UK Biobank
  13. 2013
    “…These molecules, when ingested by humans, can be catabolized into uric acid, contributing to uric acid’s level increase in serum, which may lead to hyperuricemia and gout. To assure a proper management of this disease, physicians recommend restrictive dietary measures, particularly by avoiding the consumption of beer. …”
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    Towards the Use of Adsorption Methods for the Removal of Purines from Beer
  14. 2014
    “…The mixture exhibited a high potential for preventing gout by inhibiting a relevant key enzyme, xanthine oxidase (XO) (IC(50) = 258.22 µg/mL). …”
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    α-Amyrin and β-Amyrin Isolated from Celastrus hindsii Leaves and Their Antioxidant, Anti-Xanthine Oxidase, and Anti-Tyrosinase Potentials
  15. 2015
    “…Asymptomatic hyperuricemia (AH) is an early stage of gout. Emerging evidence shows that the intestinal microbiota is related to gout. …”
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    Gut Microbiota Characterization in Patients with Asymptomatic Hyperuricemia: probiotics increased
  16. 2016
    “…No reported incidence of gout or pseudogout post-COVID-19 vaccination has been reported despite reported cases of gout flares with other vaccines. …”
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    Septic and Crystal-Induced Arthritis (Pseudogout) Post-COVID-19 Vaccination
  17. 2017
    por Lai, Bin, Pang, Zhi-Hui
    Publicado 2022
    “…CASE SUMMARY: This is a 52-year-old Chinese male patient with a 20-year history of gouty arthritis. At admission, the gout stone in the patient’s right ankle was broken and it secreted a white mucoid substance. …”
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    Sepsis complicated with secondary hemophagocytic syndrome induced by giant gouty tophi rupture: A case report
  18. 2018
    “…We discuss the role of the inflammasome in the pathogenesis of arthritic diseases, such as rheumatoid arthritis, ankylosing spondylitis, and gout, and the potential of newly developed therapies that specifically target the inflammasome or its products for the treatment of inflammatory diseases, with a particular emphasis on treatment and clinical application.…”
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    Inflammasomes and their roles in arthritic disease pathogenesis
  19. 2019
    “…Primary gout is a hereditary disorder in nucleotide metabolism. …”
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    Tophöse Gicht als Differenzialdiagnose eines präaurikulären Tumors
  20. 2020
    por Zarco, Francisco, 1829-1869
    Publicado 1987
    Libro
    Historia del Congreso Constituyente de 1857 /
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