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  1. 2161
    “…Increasing age, a diagnosis of gout, ever smoking, having comorbidities and specific comorbidities of obesity, cardiovascular and pulmonary disease were more common in those who died. …”
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    Temporal trends in COVID-19 outcomes in people with rheumatic diseases in Ireland: data from the COVID-19 Global Rheumatology Alliance registry
  2. 2162
    “…They tend to increase considerably in patients with metabolic diseases such as chronic renal failure, hyperparathyroidism, diabetes, gout, and systemic lupus erythematosus. The reported case regards a 48-year-old man with chronic, spontaneous and simultaneous quadriceps, and contra-lateral patellar tendon rupture. …”
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    Simultaneous chronic rupture of quadriceps tendon and contra-lateral patellar tendon in a patient affected by tertiary hyperparatiroidism
  3. 2163
    por Oliver, Jacqueline E, Silman, Alan J
    Publicado 2009
    “…The major rheumatic diseases, including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, systemic lupus erythematosus, scleroderma, osteoarthritis, gout, and fibromyalgia, and chronic widespread pain, will be covered. …”
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    What epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases
  4. 2164
    “…Nalp3 has been identified as a key NLR for IL-1β production and has been shown to have a particular role in gout. These findings present new therapeutic opportunities, possibly allowing for the replacement of biologics with small molecule inhibitors.…”
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    Toll-like receptors and NOD-like receptors in rheumatic diseases
  5. 2165
    “…A 41-year-old man with a history of gout presented with an enlarging eyelid growth. Clinical examination revealed a mildly indurated nodule at the lateral canthus. …”
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    A Rare Case of Lateral Canthal Gouty Tophus Presenting as an Eyelid Mass
  6. 2166
    por Persons, Benjamin, Kissin, Eugene Y.
    Publicado 2020
    “…The “snowstorm” sign refers to the ultrasound appearance of motile hyperechoic specks within synovial fluid and has been reported to have a high specificity for gout. We describe three additional etiologies commonly encountered in the rheumatology clinic that can produce a snowstorm: calcium pyrophosphate deposition disease, fibrin collections/rice bodies, and gas bubbles in viscous synovial fluid.…”
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    Scruples over Speckles
  7. 2167
    “…Two weeks before admission, gout was developed and he took colchicine (1.2 mg b.i.d) by himself for three days. …”
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    Acute myopathy induced by colchicine in a cyclosporine-treated renal transplant recipient--a case report and review of the literature.
  8. 2168
    por Gustafsson, David, Unwin, Robert
    Publicado 2013
    “…High levels are causative in gout and urolithiasis. Hyperuricaemia has also been implicated in the pathophysiology of hypertension, chronic kidney disease (CKD), congestive heart failure (CHF), the metabolic syndrome, type 2 diabetes mellitus (T2DM), and atherosclerosis, with or without cardiovascular events. …”
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    The pathophysiology of hyperuricaemia and its possible relationship to cardiovascular disease, morbidity and mortality
  9. 2169
    por Singh, Vikas R., Bain, Gregory I.
    Publicado 2018
    “…Olecranon spur is a common underlying clinical problem in patients with inflammatory conditions such as triceps tendonitis, olecranon bursitis, and gout. It is often managed conservatively. Conventionally, symptomatic olecranon spurs that have failed conservative management are excised along with the overlying bursa using an open technique. …”
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    Endoscopic Extrabursal Excision of Olecranon Spur
  10. 2170
    por Kwee, Robert M., Kwee, Thomas C.
    Publicado 2019
    “…We review the clinical presentations, locations, imaging characteristics, and differential diagnostic considerations of myositis ossificans, tophaceous gout, benign vascular lesions, calcific tendinopathy with osseous involvement, periosteal chondroma, primary synovial chondromatosis, Hoffa’s disease, tumoral calcinosis, lipoma with metaplasia, calcifying aponeurotic fibroma, calcific myonecrosis, ancient schwannoma, and Castleman disease.…”
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    Calcified or ossified benign soft tissue lesions that may simulate malignancy
  11. 2171
    “…Lithium salts have been in the therapeutic toolbox for better or worse since the 19th century, with purported benefit in gout, hangover, insomnia, and early suggestions that lithium improved psychiatric disorders. …”
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    Lithium and Therapeutic Targeting of GSK-3
  12. 2172
    “…Immunomodulation by colchicine is a well-established therapy for targeting inflammatory pathways in gout, pericarditis and Behchet’s disease. In more recent times, evidence has emerged demonstrating a potential role for colchicine in several cardiac conditions. …”
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    Colchicine—regeneration of an old drug
  13. 2173
    “…It is vital to promote research on RHUC, as this will lead not only to the elucidation of its pathophysiology but also to the development of new treatments for gout and hyperuricemia.…”
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    Hypouricemia and Urate Transporters
  14. 2174
    “…Multivariate logistic regression analysis was assessed influencing factors for the acute gout attack. ROC curves were plotted to evaluate their diagnostic value for AG. …”
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    New Inflammatory Marker Associated with Disease Activity in Gouty Arthritis: The Systemic Inflammatory Response Index
  15. 2175
    “…INTRODUCTION: Gout affects 2.5% of the UK's adult population and is now the most common type of inflammatory arthritis. …”
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    Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia
  16. 2176
    “…The main diseases were adult-onset Still’s disease (AOSD) (35), gout (28), systemic juvenile idiopathic arthritis (27), cryopyrin-associated periodic syndrome (CAPS) (21), familial Mediterranean fever (14) and mevalonate kinase deficiency (12). …”
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    Tolerance and efficacy of off-label anti-interleukin-1 treatments in France: a nationwide survey
  17. 2177
    “…CONCLUSIONS: In this “real-world” setting, many patients with gout not surprisingly were not treated with maximum permitted doses of allopurinol. …”
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    A Real-World Study of Switching From Allopurinol to Febuxostat in a Health Plan Database
  18. 2178
    por Singh, Jasvinder A., Cleveland, John
    Publicado 2017
    “…BACKGROUND: There are no published human studies investigating whether the use of allopurinol, the most commonly used medication for the treatment of hyperuricemia in gout, the most common type of inflammatory arthritis in adults, has any beneficial effects on ventricular electrophysiology. …”
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    Allopurinol and the risk of ventricular arrhythmias in the elderly: a study using US Medicare data
  19. 2179
    “…BACKGROUND: The use of allopurinol in people with chronic kidney disease (CKD) remains one of the most controversial areas in gout management. The aim of this study was to determine the effect of baseline kidney function on safety and efficacy of allopurinol dose escalation to achieve serum urate (SU) <6 mg/dl. …”
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    The effect of kidney function on the urate lowering effect and safety of increasing allopurinol above doses based on creatinine clearance: a post hoc analysis of a randomized controlled trial
  20. 2180
    “…These data support further evaluation of once-daily verinurad as a treatment for gout and asymptomatic hyperuricemia.…”
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    Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy Japanese and non-Asian male subjects
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