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  1. 2241
    por Abou-Elela, A.
    Publicado 2017
    “…Other various causes of calculus formation comprises of chronic diarrhea, renal hyperuricosuria, insulin resistance, primary gout, extra purine in the diet, neoplastic syndromes, and congenital hyperuricemia. …”
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    Epidemiology, pathophysiology, and management of uric acid urolithiasis: A narrative review
  2. 2242
    por Nakayama, Masafumi
    Publicado 2018
    “…Endogenous crystals such as monosodium urate, cholesterol, and hydroxyapatite are associated with pathogenesis of gout, atherosclerosis, and osteoarthritis, respectively. …”
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    Macrophage Recognition of Crystals and Nanoparticles
  3. 2243
    por Hong, Fan, Xu, Pengfei, Zhai, Yonggong
    Publicado 2018
    “…Peroxisome proliferator-activated receptors (PPARs) are a well-known pharmacological target for the treatment of multiple diseases, including diabetes mellitus, dyslipidemia, cardiovascular diseases and even primary biliary cholangitis, gout, cancer, Alzheimer’s disease and ulcerative colitis. …”
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    The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development
  4. 2244
    por Koo, John, Deans, Gregory D.
    Publicado 2018
    “…A 67-year-old man with a history of opioid use disorder, osteoarthritis, and gout but no known immunocompromise was admitted to hospital with pain and swelling of his right knee. …”
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    A Rare Case of Burkholderia cepacia Complex Septic Arthritis
  5. 2245
    por Wheeler, Emily, Thomas, Suresh
    Publicado 2019
    “…Uromodulin kidney disease (UKD) is a subtype of autosomal dominant tubulointerstitial kidney disease (ADTKD), and is a rare cause of renal failure and gout in young people. Although it is inherited in an autosomal dominant fashion, the gene mutation exhibits variable expressivity so the phenotype varies dramatically among affected individuals. …”
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    Diagnosis and Long-term Management of Uromodulin Kidney Disease
  6. 2246
    “…Necropsies detected pale and swollen kidneys with signs of gout, enlarged and fragile livers, and pale hearts. …”
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    Novel Orthobunyavirus Causing Severe Kidney Disease in Broiler Chickens, Malaysia, 2014–2017
  7. 2247
    “…These can occur due to the disease process or infection; contrary to what many people think, rheumatologic emergencies like a pain, rheumatic crisis, or attack gout do not compromise the patient's life. This article mentioned only true emergencies: catastrophic antiphospholipid syndrome (cAPS), kidney-lung syndrome, central nervous system (CNS) vasculitis, anti-Ro syndrome (neonatal lupus), and macrophage activation syndrome (MAS). …”
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    Rheumatologic emergencies
  8. 2248
    “…She was diagnosed with an acute gout flare, and her symptoms significantly improved with steroids and anti-inflammatory treatment. …”
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    Crystal Arthropathy in the Setting of Total Knee Arthroplasty
  9. 2249
    “…Colchicine is an anti-inflammatory agent which has been used for decades in the treatment of gout. The drug has a number of dermatological indications like Psoriasis, Sweet's syndrome, aphthosis, Behcet's disease, erythema nodosum, leukocytoclastic vasculitis and is consistently effective in neutrophilic disorders. …”
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    Colchicine in Dermatology: Rediscovering an Old Drug with Novel Uses
  10. 2250
    “…Furthermore, monosodium urate crystals that induce gout have been shown to collect in the popliteal groove and thus may lead to degeneration and isolated tearing. …”
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    Open Popliteal Tendon Repair
  11. 2251
    “…Gout as well as asymptomatic hyperuricemia have been associated with several traditional cardiovascular risk factors and chronic kidney disease. …”
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    Treating Hyperuricemia: The Last Word Hasn’t Been Said Yet
  12. 2252
    por Gliszczyńska, Anna, Nowaczyk, Marta
    Publicado 2021
    “…However, despite its high therapeutic efficacy in relieving the symptoms of certain arthritis and in treating gout or collagen diseases, administration of IND causes a number of adverse effects, such as gastrointestinal ulceration, frequent central nervous system disorders and renal toxicity. …”
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    Lipid Formulations and Bioconjugation Strategies for Indomethacin Therapeutic Advances
  13. 2253
    por Homolya, László
    Publicado 2021
    “…Since ABCG2 plays a pivotal role in uric acid clearance, its malfunction may lead to hyperuricemia and gout. On the other hand, ABCG2 residing in various barrier tissues is involved in the innate defense mechanisms of the body; thus, genetic alterations in ABCG2 may modify the absorption, distribution, excretion of potentially toxic endo- and exogenous substances. …”
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    Medically Important Alterations in Transport Function and Trafficking of ABCG2
  14. 2254
    “…It is the aim of this work to critically review and summarize recent literature reports on the role of microbiota and mechanisms involved in the progress and development of major human diseases, which include obesity, hypertension, cardiovascular disease, diabetes, cancer, Inflammatory Bowel Disease (IBD), gout, depression and arthritis, as well as infant health and longevity.…”
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    Revisit gut microbiota and its impact on human health and disease
  15. 2255
    por Zhao, Yuetong, Song, Xia
    Publicado 2022
    “…It has also been used successfully to test urine and serum samples from healthy and gout patients.…”
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    An Electrochemical-Based Point-of-Care Testing Methodology for Uric Acid Measurement
  16. 2256
    “…Gout and hyperuricemia are present in 25% and 60% of patients with chronic kidney disease (CKD), respectively. …”
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    Uric Acid and Chronic Kidney Disease: Still More to Do
  17. 2257
    “…Case Presentation: A 42-year-old man with a history of gout and anemia presented with fevers, chills, unintentional weight loss, and productive cough for two weeks. …”
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    FRI215 Rifampin Induced Adrenal Insufficiency
  18. 2258
    “…The prevalence of hyperuricemia and gout increased after the 1980s, but it remains lower than that in developed countries. …”
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    Rheumatic Diseases in China
  19. 2259
    “…Only one outcome from Mendelian randomisation studies (increased risk of gout with high SUA levels) presented convincing evidence. …”
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    Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies
  20. 2260
    “…Adjusting parameters included demographic (age, sex, race, region, and index year) and clinical (nephrolithiasis, gout, hypercalciuria, hypertension, diabetes, and thiazide diuretic use) characteristics at baseline. …”
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    MON-523 Risk of Nephrolithiasis and Nephrocalcinosis in Patients with Chronic Hypoparathyroidism (HypoPT)
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