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2401“…Urate is a Janus-faced molecule that acts physiologically as a protective antioxidant but provokes inflammation and gout when it precipitates at high concentrations. …”
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2402por Sharma, Meenakshi, Dhaliwal, Inderpreet, Rana, Kusum, Delta, Anil Kumar, Kaushik, Prashant“…With these pharmacological activities, D. stramonium is potentially used to treat numerous human diseases, including ulcers, inflammation, wounds, rheumatism, gout, bruises and swellings, sciatica, fever, toothache, asthma, and bronchitis. …”
Publicado 2021
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2403por Zhang, Mei, Zhang, Xiaolin, Tian, Taoran, Zhang, Qi, Wen, Yuting, Zhu, Junyao, Xiao, Dexuan, Cui, Weitong, Lin, Yunfeng“…Therefore, we believe that Cur-TFNAs have great prospects for the prevention of gout and similar inflammatory diseases.…”
Publicado 2021
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2404por Maloberti, Alessandro, Biolcati, Marco, Ruzzenenti, Giacomo, Giani, Valentina, Leidi, Filippo, Monticelli, Massimiliano, Algeri, Michela, Scarpellini, Sara, Nava, Stefano, Soriano, Francesco, Oreglia, Jacopo, Sacco, Alice, Morici, Nuccia, Oliva, Fabrizio, Piani, Federica, Borghi, Claudio, Giannattasio, Cristina“…While its association with articular gout and kidney disease has been known for a long time, new data have demonstrated that UA is also related to cardiovascular (CV) diseases. …”
Publicado 2021
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2405“…More importantly, Eri was active ex vivo for synovial fluid cells and monocytes from patients with IAV infection and gout. Eri may serve as a potential novel therapeutic compound against NLRP3-driven diseases.…”
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2406por Wittmann, Nico, Behrendt, Ann-Kathrin, Mishra, Neha, Bossaller, Lukas, Meyer-Bahlburg, Almut“…Although inflammasomes are important for many diseases such as periodic fever syndromes, COVID-19, gout, sepsis, atherosclerosis and Alzheimer’s disease, only a little knowledge exists on the precise and cell type specific occurrence of inflammasome activation in patient samples ex vivo. …”
Publicado 2021
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2407“…Fallopia aubertii (L.Henry) Holub (Polygonaceae), a woody plant with a voluble stem, is used as a folk herbal medicines for the treatment of gout, fever and pneumonia. To better understand the molecular genetics of F. aubertii, its complete chloroplast genome was sequenced and annotated. …”
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2408“…The efficacy of metformin has been investigated in preclinical and clinical studies on rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, Sjögren’s syndrome, scleroderma, ankylosing spondylitis, and gout. In this review, we discuss the potential mechanisms through which metformin exerts its therapeutic effects in these diseases, focusing particularly on rheumatoid arthritis and osteoarthritis.…”
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2409por Zhang, Miao, Lv, Xuan, Wang, Bei, Yu, Shengzu, Lu, Qi, Kan, Ying, Wang, Xiqiang, Jia, Beiping, Bi, Zhuangli, Wang, Qing, Zhu, Yingqi, Wang, Guijun“…Goose astrovirus (GAstVs) is an emerging pathogen of goslings that causes fatal gout, kidney hemorrhages, renomegaly, and high mortality. …”
Publicado 2021
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2410por Li, Dan, Xu, Kun-yan, Zhao, Wei-peng, Liu, Ming-feng, Feng, Rui, Li, De-qiang, Bai, Jing, Du, Wen-li“…The management of hemorrhagic diseases and other commonly refractory diseases (including gout, inflammatory diseases, cancer, pain of various forms and causes) are very challenging in clinical practice. …”
Publicado 2022
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2411“…Inflammation of DIPB occurs commonly due to either direct trauma or overuse, but other rare causes have also been reported in the literature including infection, juvenile idiopathic arthritis, gout, and juvenile ankylosing spondylitis. We report a case of chronic inflammation of DIPB caused by direct trauma and associated with patellar tendinopathy. …”
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2412“…The patient was taking indomethacin for a gout flare prior to the episode and clinical suspicion was a peptic ulcer disease as the culprit for the bleeding. …”
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2413“…The chicken astrovirus (CAstV) is a ubiquitous enteric RNA virus that has been associated mainly with conditions, such as the runting-stunting syndrome, severe kidney disease, visceral gout, and white chick syndrome, in broiler-type chickens worldwide. …”
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2414“…In traditional medicine, Alpinia oxyphylla Miquel seed has been used to treat gout and hyperuricemia-related symptoms by enhancing kidney functions. …”
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2415por El-Shazly, Mohamed, Tai, Chi-Jung, Wu, Tung-Ying, Csupor, Dezső, Hohmann, Judit, Chang, Fang-Rong, Wu, Yang-Chang“…Aconitum and its products have been used in Asia for centuries to treat various ailments, including arthritis, gout, cancer, and inflammation. In general, their preparations and dispensing have been restricted to qualified folk medicine healers due to their low safety index and reported toxicity. …”
Publicado 2015
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2416por Luo, Zhipan, Yang, Fan, Hong, Shaocheng, Wang, Jianpeng, Chen, Bangjie, Li, Liangyun, Yang, Junfa, Yao, Yan, Yang, Chenchen, Hu, Ying, Wang, Shuxian, Xu, Tao, Wu, Jun“…The condition is triggered by a disorder of uric acid metabolism, which causes urate deposition and gout flares. MicroRNAs are a class of conserved small non-coding RNAs that bind to the 3’ untranslated region (UTR) of mRNA and regulate the expression of a variety of proteins at the post-transcriptional level. …”
Publicado 2022
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2417“…Colchicine is a tricyclic, lipid-soluble alkaloid which has long been used to treat gout and many immunological diseases. Due to its narrow therapeutic window and long half-life of elimination, colchicine overdose occurs occasionally. …”
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2418por Živná, Martina, Kidd, Kendrah O., Barešová, Veronika, Hůlková, Helena, Kmoch, Stanislav, Bleyer, Anthony J.“…ADTKD‐UMOD is also associated with hyperuricemia and gout. ADTKD‐REN often presents in childhood with mild hypotension, CKD, hyperkalemia, acidosis, and anemia. …”
Publicado 2022
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2419“…Xanthine oxidase (XO) is a key target for gout treatment. Great efforts have been made towards the discovery and development of new XO inhibitors. …”
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2420“…In addition to this, neglected non-communicable diseases (NNCD) in the form of gout, sickle cell disease, accidents and many more are likely to be one of the biggest public health challenges soon. …”
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