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  1. 3241
    “…Objective: The issue of when to start treatment in patients with hyperuricemia (HUA) without gout and chronic kidney disease (CKD) is both important and controversial. …”
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    Rapid identification of early renal damage in asymptomatic hyperuricemia patients based on urine Raman spectroscopy and bioinformatics analysis
  2. 3242
    “…Compared with adults with obesity and 0 healthy lifestyle factors, individuals with obesity who met all 4 healthy lifestyle factors were at lower risk of hypertension (HR, 0.84; 95% CI, 0.78-0.90), ischemic heart disease (HR, 0.72; 95% CI, 0.65-0.80), arrhythmias (HR, 0.71; 95% 0.61-0.81), heart failure (HR, 0.65; 95% CI, 0.53-0.80), arteriosclerosis (HR, 0.19; 95% CI, 0.07-0.56), kidney failure (HR, 0.73; 95% CI, 0.63-0.85), gout (HR, 0.51; 95% CI, 0.38-0.69), sleep disorders (HR, 0.68; 95% CI, 0.56-0.83), and mood disorders (HR, 0.66; 95% CI, 0.56-0.78). …”
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    Association of Healthy Lifestyle Factors and Obesity-Related Diseases in Adults in the UK
  3. 3243
    “…Indomethacin belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and is used as an effective intervention in the treatment of gout- or osteoarthritis-related inflammation. However, its clinical use is strongly limited since indomethacin inhibits gastric mucosal prostaglandin (PG) biosynthesis, predisposing to or even inducing ulcerogenesis. …”
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    Hydrogen Sulfide-Releasing Indomethacin-Derivative (ATB-344) Prevents the Development of Oxidative Gastric Mucosal Injuries
  4. 3244
    “…Therefore, for medical students as well as the daily health care of patients, weight control is recommended to better combat obesity-related diseases, for example, cardiopulmonary diseases, gout and diabetes.…”
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    Body Mass Index is Associated with blood pressure and vital capacity in medical students
  5. 3245
    “…Children and adolescents who were older, female, and obese and had dyslipidemia, gout, or psychiatric disorders had a significantly higher risk of youth-onset type 2 diabetes than children without those characteristics. …”
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    Parental Income Level and Risk of Developing Type 2 Diabetes in Youth
  6. 3246
    por Kolz, Melanie, Johnson, Toby, Sanna, Serena, Teumer, Alexander, Vitart, Veronique, Perola, Markus, Mangino, Massimo, Albrecht, Eva, Wallace, Chris, Farrall, Martin, Johansson, Åsa, Nyholt, Dale R., Aulchenko, Yurii, Beckmann, Jacques S., Bergmann, Sven, Bochud, Murielle, Brown, Morris, Campbell, Harry, Connell, John, Dominiczak, Anna, Homuth, Georg, Lamina, Claudia, McCarthy, Mark I., Meitinger, Thomas, Mooser, Vincent, Munroe, Patricia, Nauck, Matthias, Peden, John, Prokisch, Holger, Salo, Perttu, Salomaa, Veikko, Samani, Nilesh J., Schlessinger, David, Uda, Manuela, Völker, Uwe, Waeber, Gérard, Waterworth, Dawn, Wang-Sattler, Rui, Wright, Alan F., Adamski, Jerzy, Whitfield, John B., Gyllensten, Ulf, Wilson, James F., Rudan, Igor, Pramstaller, Peter, Watkins, Hugh, Doering, Angela, Wichmann, H.-Erich, Spector, Tim D., Peltonen, Leena, Völzke, Henry, Nagaraja, Ramaiah, Vollenweider, Peter, Caulfield, Mark, Illig, Thomas, Gieger, Christian
    Publicado 2009
    “…Elevated serum uric acid levels cause gout and are a risk factor for cardiovascular disease and diabetes. …”
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    Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations
  7. 3247
    “…Co-morbidities were common, particularly hypertension (49.7%), dyslipidaemia (40.1%) and gout (15.9%). Baseline and 6 month measures were available for 91% control and 79% intervention participants. …”
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    The effectiveness of a primary care nursing-led dietary intervention for prediabetes: a mixed methods pilot study
  8. 3248
    “…Regardless of BMI, weight gain was associated with elevated risks of type 2 diabetes, hypertension, fatty liver disease, stroke, gout, and gallstones, particularly for type 2 diabetes (HR, 7.87; 95% CI, 6.91-8.97 for women; HR, 4.95; 95% CI, 4.23-5.79 for men) and fatty liver disease (HR, 3.68; 95% CI, 3.42-3.95 for women; HR, 2.83, 95% CI, 2.56-3.13 for men) in individuals with weight gain of 20 kg or more compared with those with a healthy weight. …”
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    Association of Adult Weight Gain With Major Health Outcomes Among Middle-aged Chinese Persons With Low Body Weight in Early Adulthood
  9. 3249
    “…Short sleepers had a higher prevalence of chronic diseases, including anemia (6.2%, p = 0.024), gout (2.8%, p = 0.010), hyperlipidemia (3.9%, p = 0.003) and low back pain (5.6%, p = 0.020) than other types of sleeper. …”
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    Relationship between sleep duration and sociodemographic characteristics, mental health and chronic diseases in individuals aged from 18 to 85 years old in Guangdong province in China: a population-based cross-sectional study
  10. 3250
    “…PATIENTS: Patients aged ≥ 18 years with a laboratory test order for at least one of 17 indications: cardiovascular disease management, hypertension, check-up, chronic kidney disease (CKD), thyroid disease, type 2 diabetes mellitus, fatigue, anemia, liver disease, gout, suspicion of acute coronary syndrome (ACS), suspicion of lung embolism, rheumatoid arthritis, sexually transmitted infections (STI), acute diarrhea, chronic diarrhea, and follow-up of medication. …”
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    Clinical decision support improves the appropriateness of laboratory test ordering in primary care without increasing diagnostic error: the ELMO cluster randomized trial
  11. 3251
    “…METHODS: Following an overnight fast, 100 healthy participants without gout attended a study visit. Blood and urine samples were taken prior to and over 180 min after 1.5 g oral inosine. …”
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    Effect of body mass index on serum urate and renal uric acid handling responses to an oral inosine load: experimental intervention study in healthy volunteers
  12. 3252
    “…It is well known for its natural bioactive compound colchicine which exhibits a wide range of pharmacological activities i.e. rheumatism, gout and was also introduced into clinical practices. …”
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    Screening the elite chemotypes of Gloriosa superba L. in India for the production of anticancer colchicine: simultaneous microwave-assisted extraction and HPTLC studies
  13. 3253
    “…Compared to other groups, in the eGFR < 45 mL/min/1.73 m(2) group, the prevalence rates of hypertension, diabetes mellitus, coronary artery disease, congestive heart failure, valvular heart disease, and gout were significantly higher (P = 0.013, P = 0.030, P = 0.001, P < 0.001, P = 0.043, and P < 0.001, respectively). …”
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    Association between estimated glomerular filtration rate and clinical outcomes in ischemic stroke patients with high-grade carotid artery stenosis
  14. 3254
    por Joshi, Hareesh, Earle, Kenneth
    Publicado 2021
    “…Clinical Case: A 64-year-old man (BMI 25kg/m2, weight 75kg) with past medical history of type 2 diabetes mellitus (on metformin and sitagliptin; glycated haemoglobin 51 mmol/mol, n<42mmol/mol), hypertension, G6PD deficiency and gout was admitted to hospital with COVID pneumonitis and type 1 respiratory failure giving 5 days’ history of cough, shortness of breath, fatigue and tiredness. …”
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    SARS-CoV-2 Trigger in Severe Insulin Resistance With Acute Haemolytic Crisis in Diabetes and Glucose-6-phosphate Dehydrogenase Deficiency
  15. 3255
    “…BACKGROUND: Plantaginis Semen has been widely used as folk medicine and health care food against hyperuricemia (HUA) and gout, but its pharmacological mechanism remains unclear. …”
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    Lipidomics study of the therapeutic mechanism of Plantaginis Semen in potassium oxonate-induced hyperuricemia rat
  16. 3256
    “…Two hundred and six adults with acute flare of gout, and visual analogue scale (VAS) score of joint pain ≥ 3 points will be recruited. …”
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    Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial
  17. 3257
    “…Les participants séropositifs ont signalé plus fréquemment une perte d'odorat (16,7 % vs. 4,7 %) et une perte de goût (17,7 % vs. 4,1 %) depuis mars 2020. La séropositivité était significativement associée à un nombre moyen plus élevé de détenus par cellule (1,9 vs. 1,8 ; p=0,0088) et présence plus fréquente de co-détenus malades (41,3 % vs. 32,4 % ; p=0,003). …”
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    Évaluation de la séroprévalence du SARS-CoV-2 en détention
  18. 3258
    “…CLINICAL CASE: A 59-year-old Caucasian female with history of T2DM, GERD, gout, and bowel resection for an incarcerated abdominal hernia three weeks ago presented to the emergency department due to seizure-like movements. …”
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    LBSAT127 An Underrecognized Entity: Hypercalcemia Induced PRES
  19. 3259
    “…Revision forefoot surgeries, concomitant flatfoot reconstruction or ankle replacement, and patients with history of rheumatoid arthritis or gout were excluded. PROMIS scores in six key domains were compared between groups both preoperatively and at one year postoperatively. …”
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    Lapidus with 1st Metatarsal-Intermediate Cuneiform Fixation Improves Rotational Correction of Hallux Valgus
  20. 3260
    “…BACKGROUND: Allopurinol is used to treat hyperuricemia and gout. It is metabolized to oxypurinol by xanthine oxidase (XO), and aldehyde oxidase (AO). …”
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    Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats
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