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Século 20
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701por Shirvani-Rad, Salman, Khatibzade-Nasari, Niloufar, Ejtahed, Hanieh-Sadat, Larijani, Bagher“…OBJECTIVES: Gut dysbiosis is believed to be one of the several mechanisms that are involved in the pathogenesis of gout. This systematic review aimed to summarize the role of gut dysbiosis in gout disease and uncover the underlying mechanisms. …”
Publicado 2023
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702por Orchard, G. E.“…Gout with associated AA amyloidosis is an unusual finding. …”
Publicado 2023
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703por Tabi-Amponsah, Adwoa Dansoa, Stewart, Sarah, Hosie, Graham, Stamp, Lisa K., Taylor, William J., Dalbeth, Nicola“…Urate-lowering therapies for the management of gout lead to a reduction in serum urate levels, monosodium urate crystal deposition, and the clinical features of gout, including painful and disabling gout flares, chronic gouty arthritis, and tophi. …”
Publicado 2023
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704
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705“…About 600,000 Americans have early-onset gout (EOG), generally defined as first gout attack at ≤ 40 years of age. …”
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706“…Tophaceous gout is the systemic deposition of uric acid which can induce cutaneous ulceration. …”
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707por Wu, Eric Q., Patel, Pankaj A., Yu, Andrew P., Mody, Reema R., Cahill, Kevin E., Tang, Jackson, Krishnan, Eswar“…Older adults with gout are of particular interest because they tend to experience higher rates of tophi, an advanced stage of gout, than do younger patients. …”
Publicado 2008
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708por Tsiamalou, Paraskevi, Brotis, Alexandros G., Vrekou, Eleni, Georgakopoulou, Vasiliki Epameinondas, Papalexis, Petros, Aravanatinou-Fatorou, Aikaterini, Tegousi, Maria, Fotakopoulos, George, Paterakis, Konstantinos“…The current treatment of gout is largely suboptimal, with up to 89% of hospitalizations being preventable due to inadequate care. …”
Publicado 2023
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709“…Observational studies have reported some associations between thyroid disease and gout, but the causal relationship between the 2 is not clear. …”
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710por Wang, Jiwei, Hao, Peiqi, Sun, Xianrun, Ward, Richard, Tang, Tao, Chen, Xi, Liu, Yihong, Luo, Guancong, Yang, Yang, Xiang, Cheng, An, Su, Xu, Tian-Rui“…Therefore, our objective was to develop a novel chronic mouse model of gout that more closely mimics the progression of gout in humans. …”
Publicado 2023
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711“…A rapid and massive raise of uric acid, during tumor lysis syndrome (TLS), and also a lower and chronic hyperuricemia, as in gout, mainly damage the kidney. To prevent or treat these consequences, a new therapeutic option is represented by rasburicase, a recombinant form of an enzyme, urate oxidase. …”
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712“…Large aggregates of monosodium urate crystals in patients with longstanding chronic tophaceous gout can serve as the inciting antigen for the development of granuloma, but hypercalcemia has not been described in this context. …”
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713por Annemans, L, Spaepen, E, Gaskin, M, Bonnemaire, M, Malier, V, Gilbert, T, Nuki, G“…OBJECTIVE: To investigate and compare the prevalence, comorbidities and management of gout in practice in the UK and Germany. METHODS: A retrospective analysis of patients with gout, identified through the records of 2.5 million patients in UK general practices and 2.4 million patients attending GPs or internists in Germany, using the IMS Disease Analyzer. …”
Publicado 2008
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714
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715por Becker, Michael A, Schumacher, H Ralph, Espinoza, Luis R, Wells, Alvin F, MacDonald, Patricia, Lloyd, Eric, Lademacher, Christopher“…INTRODUCTION: The purpose of this study was to compare urate-lowering (UL) efficacy and safety of daily febuxostat and allopurinol in subjects with gout and serum urate (sUA) ≥ 8.0 mg/dL in a six-month trial. …”
Publicado 2010
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716“…The prevalence of gout is increasing with increased life expectancy. …”
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717por Falidas, Evangelos, Rallis, Efstathios, Bournia, Vasiliki-Kalliopi, Mathioulakis, Stavros, Pavlakis, Emmanouil, Villias, Constantinos“…INTRODUCTION: Gout is a common inflammatory arthritis caused by articular precipitation of monosodium urate crystals. …”
Publicado 2011
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718por de Ávila Fernandes, Eloy, Sandim, Gabriel B., Mitraud, Sônia A. V., Kubota, Edson S., Ferrari, Antonio J. L., Fernandes, Artur R. C.“…OBJECTIVE: To describe and classify the varied ultrasound features of tendinous involvement in relation to tophi in chronic tophaceous gout so that they are better recognised. METHODS: Ultrasound images of 138 affected areas from 31 patients with chronic tophaceous gout were analysed using high-quality broadband linear transducers. …”
Publicado 2010
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719
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720“…BACKGROUND: The incidence of gout rises with increasing age. Management of elderly (≥65 years) gout patients can be challenging due to high rates of comorbidities, such as renal impairment and cardiovascular disease, and concomitant medication use. …”
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