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  1. 1141
    “…More importantly, suppression of cAMP-PKA pathway by SQ22536 and H-89 restored NETosis instead of apoptosis in GPR105(−/−) neutrophils, promoting MSU-induced gout flares. Interestingly, lobetyolin was screened out as a potent GPR105 antagonist using molecular docking-based virtual screening and in vitro activity test, which efficiently attenuated MSU-induced inflammatory response interacting with GPR105. …”
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    GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils
  2. 1142
    “…Although several epidemiologic studies have shown the association between gout and cardiovascular outcomes, specific risk factors for developing cardiovascular diseases in Asian patients with gout are undisclosed. …”
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    Cardiovascular Risks in Korean Patients with Gout: Analysis Using a National Health Insurance Service Database
  3. 1143
    “…Although GoAstV-2 is known to be the causative agent of goose gout, little published information about the relationship between GoAstV-1 and goose gout is unknown. …”
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    Isolation and phylogenetic analysis of goose astrovirus type 1 from goslings with gout in Jiangxi province, China
  4. 1144
    “…BACKGROUND: The incidence and prevalence of gout have been steadily increasing globally, which has resulted in gout research attracting consistently increased attention. …”
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    Mapping Knowledge Structure and Global Research Trends in Gout: A Bibliometric Analysis From 2001 to 2021
  5. 1145
    por Gao, Linggen, Wang, Bin, Cheng, Rui
    Publicado 2022
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    Reply to comment on “Cardiovascular safety of febuxostat compared to allopurinol for the treatment of gout: A systematic and meta‐analysis”
  6. 1146
    por Ko, Yu-Lin
    Publicado 2021
    “…Gout is the most common form of inflammatory arthritis in adults. …”
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    Genetics of hyperuricemia and gout: Insights from recent genome-wide association studies and Mendelian randomization studies
  7. 1147
    “…The first gout attack in a hyperuricaemic patient may be regarded as a nucleation event which is caused by monosodium urate monohydrate (MSUM) deposition in the synovial fluid. …”
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    Elucidating the mechanism of nucleation inhibition of pathology crystallization of gout based on the evidence from amorphous form and in solution
  8. 1148
    “…The risk of stroke in patients with gout is high. The effect of vaccines in lowering the stroke risk in patients with gout remains unclear. …”
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    Association between Stroke Risk and Influenza Vaccination in Patients with Gout: A Nationwide Population-Based Study
  9. 1149
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    Corrigendum: Whole-exome sequencing identifies a novel CPT2 mutation in a pedigree with gout
  10. 1150
    “…The disease target genes related to hyperuricemia (HUA) and gout were obtained by searching CTD, DisGeNET, DrugBank, GeneCards, OMIM, TTD, and PharmGKB databases with “Hyperuricemia” and “Gout” as keywords, respectively. …”
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    Potential molecular mechanisms of Ermiao san in the treatment of hyperuricemia and gout based on network pharmacology with molecular docking
  11. 1151
    “…Colchicine (Col) is used to prevent and treat acute gout flare; however, its therapeutic use is strictly limited owing to severe gastrointestinal side effects after oral administration. …”
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    Transdermal delivery of colchicine using dissolvable microneedle arrays for the treatment of acute gout in a rat model
  12. 1152
    “…Objective: Although influenza vaccination reduces the risk of atrial fibrillation (AF), its protective effect in patients with gout remains unclear. The present study aimed to evaluate the protective effect of influenza vaccination in patients with gout. …”
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    Influenza vaccination and risk of atrial fibrillation in patients with gout: A nationwide population-based cohort study
  13. 1153
    “…OBJECTIVE: Patients with uncontrolled/refractory gout have heavy disease burden, but few treatment options. …”
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    Community Practice Experiences with a Variety of Immunomodulatory Agents Co-Administered with Pegloticase for the Treatment of Uncontrolled Gout
  14. 1154
    “…Background: In a context of therapeutic inertia, the French Society of Rheumatology (SFR) published its first recommendations on gout in 2020, which were deliberately simple and concise. …”
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    Simple Application and Adherence to Gout Guidelines Enables Disease Control: An Observational Study in French Referral Centres
  15. 1155
    “…However, the postoperative pathological diagnosis was gout spondylitis. In this report, we show multimodal images of advanced gout spondylitis. …”
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    (99m)Tc-methylene diphosphonate SPECT/CT imaging of gout spondylitis: a case report
  16. 1156
    “…This study aimed to analyze key hub genes related to pyroptosis in gout and construct a miRNA-mRNA regulatory network using bioinformatic tools to elucidate the pathogenesis of gout and offer novel ideas to develop targeted therapeutic strategies for gout. …”
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    Key Genes Associated with Pyroptosis in Gout and Construction of a miRNA-mRNA Regulatory Network
  17. 1157
    “…OBJECTIVES: Observational studies have demonstrated associations between gout and hypertension, but whether they are causal remains unclear. …”
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    Assessing the causal relationships between gout and hypertension: a bidirectional Mendelian randomisation study with coarsened exposures
  18. 1158
    por Liu, Yuan, Luo, Di, Xu, Bo
    Publicado 2022
    “…Due to unhealthy diet and living habits, the incidence of gout is on the rise and has become a common disease with a high incidence. …”
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    The combination of molecular docking and network pharmacology reveals the molecular mechanism of Danggui Niantong decoction in treating gout
  19. 1159
    “…BACKGROUND: Gout is a progressive metabolic disease closely related to hyperuricemia and urate deposition, with an increasing prevalence and incidence across the globe. …”
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    Overnutrition-induced gout: An immune response to NLRP3 inflammasome dysregulation by XOD activity increased in quail
  20. 1160
    “…This study sought to clarify the mechanism of action of Miao medicine Tongfengting decoction in the treatment of gout through network pharmacology and molecular docking by searching for its key targets and related pathways. …”
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    The mechanism study of Miao medicine Tongfengting decoction in the treatment of gout based on network pharmacology and molecular docking
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