“…INTRODUCTION: This 24-week randomized, double-blind, non-inferiority study compared the efficacy and safety of febuxostat, a xanthine oxidase inhibitor, with allopurinol using an up-titration method in hyperuricemic Chinese subjects with or without gout. METHODS: Eligible adults (serum uric acid [SUA] > 7.0 mg/dl with a history of gout, SUA ≥ 8.0 mg/dl with complications or SUA ≥ 9.0 mg/dl without complications) were randomized (1:1:1) to febuxostat 40 mg/day, 80 mg/day, or allopurinol 300 mg/day. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Natural product dietary supplements (NPDS) are frequently used for the treatment of gout, but reliable efficacy and safety data are generally lacking or not well organized to guide clinical decision making. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study aimed to contribute to the development of an ICF core set for gout through patient opinion derived from focus groups and interviews. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Serum uric acid (UA) is a terminal metabolite of purine compound, while hyperuricemia (HU) and UA crystals are recognized causes of gout. Several studies have investigated the correlations between HU, gout and OA, but the findings are inconclusive. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The objective of this study was to evaluate the properties and locations of colour-coded DECT lesions in gout patients. METHODS: DECT of the hands, knees and feet were performed in patients with suspected gout using factory default gout settings, and colour-coded DECT lesions were registered. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONTEXT: While urolithiasis is epidemiologically and mechanistically linked to gout, urologic stone disease is not actively investigated in gout patients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Although gout is rare in children, chronic sustained hyperuricemia can lead to monosodium urate deposits progressing to gout, just as in adults. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Objectives: Gout is the most common form of inflammatory arthritis and was found to be independently associated with incident dementia in the elderly. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Gout is a painful inflammatory arthritis affecting more than 8 million Americans. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Introduction A systematic review and meta-analysis of the available randomized controlled trials (RCTs) were conducted to investigate the efficacy and safety of dotinurad in hyperuricemic patients with or without gout. Dotinurad is a novel selective urate reabsorption inhibitor (SURI) that increases uric acid excretion by selectively inhibiting urate transporter 1 (URAT1). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVE: To evaluate the taxonomic composition of the gut microbiome in gout patients with and without tophi formation, and predict bacterial functions that might have an impact on urate metabolism. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVE: To investigate whether baseline monosodium urate (MSU) burden estimated by ultrasound (US) predicts the achievement of the 2016 remission criteria for gout after 12 months. METHODS: In this 12-month prospective, observational and single-center study, patients with gout fulfilling all the domains of the 2016 preliminary remission criteria for gout at baseline and on urate-lowering therapy (ULT) for at least the preceding 6 months were consecutively enrolled. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…INTRODUCTION: Elevated serum urate (SU) concentration is the central risk factor for the development of gout. The aim of this study was to examine the incidence of gout in people with low and normal SU levels (< 7.00 mg/dL). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVES: Gout, caused by chronic elevation of serum uric acid levels, is the commonest form of inflammatory arthritis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVES: To assess the cost-effectiveness of various combinations of urate lowering therapy (ULT) and anti-inflammatory treatment in the management of newly diagnosed gout patients, from the Dutch societal perspective. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We present the case of a 60-year-old man with a history of severe tophaceous gout with polyarticular involvement who came to the emergency room due to direct trauma to the right forearm and knee. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVES: The objective of this study was to develop and validate a prediction model for renal urate underexcretion (RUE) in male gout patients. METHODS: Men with gout enrolled from multicenter cohorts in China were analyzed as the development and validation data sets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Excess mortality in gout has been attributed to cardiovascular diseases (CVD). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso

“…We evaluated the association between dyslipidemia and gout in a large cohort from the Korean National Health Insurance Service-Health Screening Cohort. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso