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1501por Hershfield, Michael S, Ganson, Nancy J, Kelly, Susan J, Scarlett, Edna L, Jaggers, Denise A, Sundy, John S“…INTRODUCTION: Pegloticase, a PEGylated recombinant porcine uricase, is approved for treating refractory gout at a dose of 8 mg intravenous (IV) every 2 weeks. …”
Publicado 2014
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1502“…Tophaceous gout complicated by septic arthritis presents a management dilemma which can often require multiple surgical debridements. …”
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1503“…RESULTS: There were 371 incident cases (231 men and 140 women) of gout over the follow-up of 140 421 person-years. …”
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1504“…BACKGROUND: To identify spatiotemporal gait parameters and plantar pressure distribution during barefoot walking in people with gout and people with asymptomatic hyperuricemia by comparing them to healthy individuals with normal serum urate concentrations. …”
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1505por Mokuda, Sho, Kanno, Masamoto, Takasugi, Kiyoshi, Okumura, Chikara, Ito, Yuki, Masumoto, Junya“…Chronic tophaceous gout is the end stage of gout. We employed a blockade of interleukin-6 signaling therapy by tocilizumab instead of anakinra, an interleukin-1 receptor antagonist, for a 61-year-old Japanese woman diagnosed with tophaceous gout. …”
Publicado 2014
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1506por Xie, Zhijun, Wu, Huaxiang, Jing, Xiaoqing, Li, Xiuyang, Li, Yasong, Han, Yongmei, Gao, Xiangfu, Tang, Xiaopo, Sun, Jing, Fan, Yongshen, Wen, Chengping“…TRIAL DESIGN: In the double-blind, randomized, controlled trial, we aimed to evaluate the effects of compound tufuling oral liquid (CoTOL) on serum uric acid (sUA) levels and recurrence of acute gouty arthritis in intercritical and chronic gout treatment. METHODS: A total of 210 patients with gout were screened from 8 hospitals to observe the sUA and acute gouty arthritis recurrence rate-reducing effects of CoTOL in intercritical and chronic gout during a 12-week treatment. …”
Publicado 2017
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1507por Bardin, Thomas, Keenan, Robert T, Khanna, Puja P, Kopicko, Jeff, Fung, Maple, Bhakta, Nihar, Adler, Scott, Storgard, Chris, Baumgartner, Scott, So, Alexander“…RESULTS: Patients (n=610) were predominantly male, with mean (±SD) age 51.2±10.90 years, gout duration 11.5±9.26 years and baseline sUA of 6.9±1.2 mg/dL (410±71 µmol/L). …”
Publicado 2017
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1508por Nkeck, Jan René, Singwé Ngandeu, Madeleine, Ama Moor, Vicky, Nkeck, Jériel Pascal, Chedjou, Jean-Pierre, Ndoadoumgue, Aude Laetitia, Mbacham, Wilfred F.“…OBJECTIVE: To determine the association of non-synonymous variants rs2280205 and rs2276961 of the SLC2A9 gene to gout in Cameroonians. RESULTS: In a case–control study including 30 patients with acute gout matched to 30 healthy volunteers. …”
Publicado 2018
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1509por Pascart, Tristan, Capon, Benoist, Grandjean, Agathe, Legrand, Julie, Namane, Nasser, Ducoulombier, Vincent, Motte, Marguerite, Vandecandelaere, Marie, Luraschi, Hélène, Godart, Catherine, Houvenagel, Eric, Norberciak, Laurène, Budzik, Jean-François“…BACKGROUND: Gout is associated with higher cardiovascular risk that increases with disease severity. …”
Publicado 2018
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1510por Akashi, Airi, Nakayama, Akiyoshi, Kamatani, Yoichiro, Higashino, Toshihide, Shimizu, Seiko, Kawamura, Yusuke, Imoto, Misaki, Naito, Mariko, Hishida, Asahi, Kawaguchi, Makoto, Takao, Mikiya, Matsuo, Michinori, Takada, Tappei, Ichida, Kimiyoshi, Ooyama, Hiroshi, Shinomiya, Nariyoshi, Matsuo, Hirotaka“…Gout, which results from elevated serum uric acid (SUA), is a common form of arthritis that is induced by urate crystals. …”
Publicado 2020
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1512por Kawaguchi, Makoto, Nakayama, Akiyoshi, Aoyagi, Yuka, Nakamura, Takahiro, Shimizu, Seiko, Kawamura, Yusuke, Takao, Mikiya, Tamura, Takashi, Hishida, Asahi, Nagayoshi, Mako, Nagase, Mitsuo, Ooyama, Keiko, Ooyama, Hiroshi, Shinomiya, Nariyoshi, Matsuo, Hirotaka“…Gout is a common type of acute arthritis that results from elevated serum uric acid (SUA) levels. …”
Publicado 2021
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1513por Kurniasari, Maria Dyah, Karwur, Ferry Fredy, Rayanti, Rosiana Eva, Dharmana, Edi, Rias, Yohanes Andy, Chou, Kuei Ru, Tsai, Hsiu-Ting“…To analyze the association between smoking status (active smoking and exposure to Second-Hand Smoking (SHS)) and the synergistic effect of smoking status and BMI with gout risk, a community-based case-control design was undertaken among 385 participants, including 304 healthy controls and 81 gout patients from seven community health services. …”
Publicado 2021
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1514por Yang, Wenning, Jiang, Xiaoquan, Liu, Jingtong, Qi, Dongying, Luo, Zhiqiang, Yu, Guohua, Li, Xueyan, Sen, Muli, Chen, Hongjiao, Liu, Wei, Liu, Yang, Wang, Guopeng“…Furthermore, it also can clarify the potential mechanism of action of TCM and rationalize the application of TFDC as an effective herbal therapy for gout.…”
Publicado 2021
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1515por Nhi, Le Huu Hanh, Minh, Le Huu Nhat, Tieu, Thuan Minh, Mostafa, Esraa Mahmoud, Karimzadeh, Sedighe, Dung, Nguyen Minh, Hai Nam, Nguyen, Phuoc, Le Van, Huy, Nguyen Tien“…Background Dual-energy computed tomography (DECT) has become a promising, non-invasive procedure for the visualization, characterization, and quantification of monosodium urate (MSU) crystals, which aids clinicians in the diagnosis of gout. In this study, we aimed to examine the diagnostic accuracy of DECT in the evaluation of gout. …”
Publicado 2021
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1516por Shen, Quan, Zhuang, Zi, Lu, Juan, Qian, Lingling, Li, Guangquan, Kanton, Aaron Gia, Yang, Shixing, Wang, Xiaochun, Wang, Huiying, Yin, Jun, Zhang, Wen“…In March 2020, a goose farm locates in Shanghai, China, where there was no goose astroviruses (GAstVs) infection reported before, experienced an outbreak of gout disease in geese. The etiological investigation was carried out by virus metagenomics and bacterial culture and two GAstVs strains, designated as CHSH01 and CHSH02, were determined. …”
Publicado 2022
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1517por Jia, Ertao, Hu, Shasha, Geng, Hongling, Zhu, Haiqiong, Xie, Jingjing, Xiao, Yuya, Jiang, Yubao, Xiao, Min, Zhang, Jianyong“…The primary outcome is the rate of acute gout flares in subjects within 12 weeks of the treatment period. …”
Publicado 2022
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1519
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1520por Kivitz, Alan, DeHaan, Wesley, Azeem, Rehan, Park, Justin, Rhodes, Sheri, Inshaw, Jamie, Leung, Sheldon S., Nicolaou, Savvas, Johnston, Lloyd, Kishimoto, Takashi K., Traber, Peter G., Sands, Earl, Choi, Hyon“…INTRODUCTION: SEL-212 is a developmental treatment for uncontrolled gout characterized by serum uric acid (sUA) levels ≥ 6 mg/dl despite treatment. …”
Publicado 2023
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