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  1. 1581
    “…BACKGROUND: Dotinurad, a novel selective urate reabsorption inhibitor (SURI), reduces serum uric acid levels by selectively inhibiting urate transporter 1 (URAT1) for the treatment of hyperuricemia with or without gout. We confirmed the serum uric acid lowering effect and safety of dotinurad. …”
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    Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: randomized, multicenter, double-blind, placebo-controlled, parallel-group, confirmatory phase 2 study
  2. 1582
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    The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol for a multicenter randomized controlled study
  3. 1583
    “…RESULTS: A total of 80 hyperuricemic patients with or without gout were enrolled and randomly assigned to the dotinurad or placebo groups. …”
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    Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: an exploratory, randomized, multicenter, double-blind, placebo-controlled, parallel-group early phase 2 study
  4. 1584
    “…Gout is regarded as a painful inflammatory arthritis induced by the deposition of monosodium urate crystals in joints and soft tissues. …”
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    3β,23-Dihydroxy-12-ene-28-ursolic Acid Isolated from Cyclocarya paliurus Alleviates NLRP3 Inflammasome-Mediated Gout via PI3K-AKT-mTOR-Dependent Autophagy
  5. 1585
    por Lo, M, Ling, V, Wang, Y Z, Gout, P W
    Publicado 2008
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    The x(c)(−) cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance
  6. 1586
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    HS and Inflammation: A Potential Playground for the Sulfs?
  7. 1587
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    A Population-Genetic Lens into the Process of Gene Loss Following Whole-Genome Duplication
  8. 1588
    “…AIM: To conduct a pharmacoepidemiological study to explore the association between sodium‐glucose cotransporter‐2 (SGLT2) inhibitors and gout in patients with type 2 diabetes mellitus (T2DM). …”
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    Sodium‐glucose cotransporter‐2 inhibitors and the risk of gout in patients with type 2 diabetes mellitus: A propensity‐score‐matched, new‐user design study with an active comparator using the IQVIA Medical Research Data UK database
  9. 1589
    “…BACKGROUND: Gout is the most common form of rheumatic disease in which monosodium urate crystals are deposited in the joints followed by acute inflammatory reactions. …”
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    Prednisolone Versus Colchicine for Acute Gout in Primary Care (COPAGO): protocol for a two-arm multicentre, pragmatic, prospective, randomized, double-blind, controlled clinical trial of prednisolone and colchicine for non-inferiority with a parallel group design
  10. 1590
    “…METHODS: Uncontrolled gout patients (serum urate [SU] ≥ 6 mg/dL and SU ≥ 6 mg/dL despite urate-lowering therapy [ULT], ULT intolerance, or functionally-limiting tophi) were included. …”
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    A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study
  11. 1591
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    The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding
  12. 1592
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    Functional specialization of Piwi proteins in Paramecium tetraurelia from post-transcriptional gene silencing to genome remodelling
  13. 1593
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    Changes in Acetyl CoA Levels during the Early Embryonic Development of Xenopus laevis
  14. 1594
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    Prostate cancer metastasis-driving genes: hurdles and potential approaches in their identification
  15. 1595
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    Precision medicine meets the DNA damage response in pancreatic cancer
  16. 1596
    “…BACKGROUND: Long-term gout treatment is based on reducing serum urate levels using urate-lowering therapy (ULT). …”
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    Urate-lowering therapy following a treat-to-target continuation strategy compared to a treat-to-avoid-symptoms discontinuation strategy in gout patients in remission (GO TEST Finale): study protocol of a multicentre pragmatic randomized superiority trial
  17. 1597
    Publicado 2008
    Libro
    Cuando viajan las estrellas [videograbación]
  18. 1598
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    Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?
  19. 1599
    por Bampfield, R. W.
    Publicado 1821
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    Some Observations on the Use of Colchicum, Tending to Prove That Gout Can Be Cured by Smaller Doses of That Medicine Than Are Exhibited by Those Who Not Only Reprobate the Use of What They Prescribe, but Deny It Any "Specific Virtue:" with Some Cursory Objections to the Gastro-Hepatic Pathology
  20. 1600
    “…INTRODUCTION: There is inconsistent association between urate transporters SLC22A11 (organic anion transporter 4 (OAT4)) and SLC22A12 (urate transporter 1 (URAT1)) and risk of gout. New Zealand (NZ) Māori and Pacific Island people have higher serum urate and more severe gout than European people. …”
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    Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects
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