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  1. 1821
    “…The root of Rumex crispus L. has been shown to possess anti-gout and anti-diabetic properties, but the compounds responsible for these pharmaceutical effects have not yet been reported. …”
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    Antioxidant, Xanthine Oxidase, α-Amylase and α-Glucosidase Inhibitory Activities of Bioactive Compounds from Rumex crispus L. Root
  2. 1822
    “…BACKGROUND: Febuxostat is a novel, orally-administered, powerful, non-purine, xanthine oxidase inhibitor used for treating gout and ceaseless tophaceous gout. The drug exhibits low bioavailability (about 49%) which is ascribed to its dissolution rate-limited absorption. …”
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    Formulation and in vitro Evaluation of Fast Dissolving Tablets of Febuxostat Using Co-Processed Excipients
  3. 1823
    “…Eighty men patients with gout were selected to analyze the correlation between blood urate and thyroid function-related hormone levels. …”
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    Thyroid Hormone-Regulated Expression of Period2 Promotes Liver Urate Production
  4. 1824
    “…Considering that gout is not easily treated and cured, further studies are explored to prevent gout development through diet modification. …”
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    Effects of β-Carotin and Green Tea Powder Diets on Alleviating the Symptoms of Gouty Arthritis and Improving Gut Microbiota in C57BL/6 Mice
  5. 1825
    “…BACKGROUND: Tophaceous gout affecting the olecranon region can result in local discomfort, skin ulceration, secondary infection, and considerable disability if left untreated. …”
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    Operative management of gouty tophi in the region of the olecranon: a case series
  6. 1826
    “…Fifteen patients with gout, 16 patients with UAS, 17 UAS patients with gout, and 17 healthy subjects were enrolled and provided fecal samples. …”
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    Association of Gut Microbiota and Biochemical Features in a Chinese Population With Renal Uric Acid Stone
  7. 1827
    “…Tophi can also promote chronic inflammatory and erosive arthritis. 2015 ACR/EULAR Gout Classification criteria include clinical, laboratory, and imaging findings, where cases of gout are indicated by a threshold score of ≥ 8. …”
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    Identification of tophi in ultrasound imaging based on transfer learning and clinical practice
  8. 1828
    “…This study investigated the potential role of microRNA (miR)-223 in the mechanism of gout. METHODS: Wild-type (WT) and miR-223 knock-out (KO) mice were used to evaluate the phenotypes of gout models. …”
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    microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3
  9. 1829
    “…BACKGROUND: Gout is the most frequent inflammatory joint disease in the western world and has a proven genetic background. …”
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    Empfehlungen der Österreichischen Gesellschaft für Rheumatologie und Rehabilitation zu Ernährung und Lebensstil bei Gicht und Hyperurikämie – Update 2022
  10. 1830
    “…Gouty panniculitis is a rare manifestation of gout. Clinically, it is characterized by indurated subcutaneous nodules in nonjoint areas. …”
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    Gouty Panniculitis with Ulcerations in a Patient with Multiple Organ Dysfunctions
  11. 1831
    “…Gout is a condition that affects over 8 million Americans. …”
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    An Optical Urate Biosensor Based on Urate Oxidase and Long-Lifetime Metalloporphyrins
  12. 1832
    “…Tophus is a characteristic manifestation of gout entering the chronic phase, which usually deposits in the joints of the extremities, skin mucosa, etc. …”
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    Multilevel Lumbar Stenosis Caused by Large Tophi Involving Both Spinal Canal and Posterior Spinal Elements: A Rare Case Report and Literature Review
  13. 1833
    “…The relationship between hyperuricemia, gout, and renal disease has been investigated for several years. …”
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    Hyperuricemia and Progression of Chronic Kidney Disease: A Review from Physiology and Pathogenesis to the Role of Urate-Lowering Therapy
  14. 1834
    “…Of the 38 charts, 37 cited a gout diagnosis (35 charts) or use of a gout medication (2 charts). …”
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    Conducting Research on the Internet: Medical Record Data Integration with Patient-Reported Outcomes
  15. 1835
    “…Methods and Results: MiR-223 was detected among 122 acute gout patients (AG), 118 intercritical gout patients (IG), and 125 healthy subjects (HC). …”
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    MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome
  16. 1836
    “…Despite many treatment options for gout, there is a substantial need for alternative treatments for patients unresponsive to current therapies. …”
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    The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice
  17. 1837
    “…RATIONALE: Gout occurs mainly in joints, but rarely in the spine. …”
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    Gouty spondylodiscitis with lumbar vertebral body retrolisthesis: A case report
  18. 1838
    por Zhang, Jihui, Lei, Hongwei, Li, Xiu
    Publicado 2021
    “…Gout is a common and complex form of arthritis that has brought great inconveniences to the normal lives of patients. …”
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    The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis
  19. 1839
    “…AIM: To evaluate the effect of empagliflozin on uric acid (UA) levels, antigout medication and gout episodes in the EMPA‐REG OUTCOME trial (NCT01131676). …”
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    Empagliflozin and uric acid metabolism in diabetes: A post hoc analysis of the EMPA‐REG OUTCOME trial
  20. 1840
    “…Urate lowering therapy is the mainstay of treatment for chronic gout. Initial treatments of choice in gout include allopurinol, a purine analog which inhibits xanthine oxidase and decreases the production of uric acid as well as probenecid which increases the urinary excretion of uric acid. …”
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    Pegloticase Induced Hemolytic Anemia in a Patient With G6PD Deficiency
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