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1841por Davidsson, Lisa, Dahlstrand Rudin, Agnes, Sanchez Klose, Felix Peter, Buck, Alicia, Björkman, Lena, Christenson, Karin, Bylund, Johan“…Gout is an inflammatory disease caused by monosodium urate (MSU) crystals. …”
Publicado 2020
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1842por He, Yikun, Dai, Chaoran, Shen, Jiaying, Chen, Qianwen, Gao, Jiandong, Pan, Xin, Gan, Jing“…BACKGROUND: The prevalence rates of gout worldwide have increased annually. Acute gouty arthritis (AGA) accounts for a large proportion of gout patients and causes severe physical and mental pain in patients. …”
Publicado 2022
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1843por Lee, Hsin-Pai, Huang, Shi-Ying, Lin, Yen-You, Wang, Hui-Min, Jean, Yen-Hsuan, Wu, Shu-Fen, Duh, Chang-Yih, Wen, Zhi-Hong“…An acute gout attack manifests in the joint as dramatic inflammation. …”
Publicado 2013
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1844“…They are pathognomonic for gout, the most common inflammatory arthritis in the United States, with an estimated lifetime prevalence of 4%. …”
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1845por Park, Ji-Eun, Yeom, Zia, Park, Keun-Tae, Han, Eun Hye, Yu, Heui Jong, Kang, Hyo Seok, Lim, Young-Hee“…The prevalence of gout is increasing worldwide, and control of serum uric acid level has been regarded as one of the therapeutic methods for gout. …”
Publicado 2018
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1846“…BACKGROUND: Gout is a monosodium urate deposition disease which is prevalent worldwide. …”
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1847“…Gout is a type of serious arthritis that is caused by hyperuricemia. …”
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1848por Kan, Yuhe, Zhang, Zhikun, Yang, Kunhao, Ti, Mengru, Ke, Yongqi, Wu, Li, Yang, Jingkui, He, Yujian“…Excessive intake of beer could increase serum uric acid levels, leading to high risk of gout, which was previously attributed to high purine content in beer. …”
Publicado 2019
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1849“…Our results show that low levels of serum testosterone levels may cause gout and T2D, while higher than normal levels of testosterone may result in RA and depression. …”
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1850por Gainche, Maël, Ogeron, Clémence, Ripoche, Isabelle, Senejoux, François, Cholet, Juliette, Decombat, Caroline, Delort, Laetitia, Berthon, Jean-Yves, Saunier, Etienne, Caldefie Chezet, Florence, Chalard, Pierre“…Filipendula ulmaria is a plant commonly used for the treatment of several pathologies, such as diarrhoea, ulcers, pain, stomach aches, fevers, and gout. Our study focused on the use of F. ulmaria for the treatment of gout disease. …”
Publicado 2021
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1851LC-MS-based metabolomics reveals the mechanism of anti-gouty arthritis effect of Wuwei Shexiang pillpor Lang, Jirui, Li, Li, Quan, Yunyun, Tan, Ruirong, Zhao, Jinbiao, Li, Min, Zeng, Jin, Chen, Shilong, Wang, Ting, Li, Yong, Zhao, Junning, Yin, Zhujun“…Wuwei Shexiang Pill (WSP) is a Tibetan traditional medicine, which has been demonstrated to exhibit potent anti-inflammatory and anti-gout effects. However, the specific pharmacological mechanism is not elucidated clearly. …”
Publicado 2023
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1852“…OBJECTIVE: Gout is the most common inflammatory arthritis associated with interleukin-1β (IL-1β) accumulation during exacerbation. …”
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1853“…BACKGROUND: Gout is a common type of inflammatory arthritis caused by the deposition of monosodium urate crystals in the joints and surrounding tissues. …”
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1854por Kannangara, Diluk RW, Ramasamy, Sheena N, Indraratna, Praveen L, Stocker, Sophie L, Graham, Garry G, Jones, Graham, Portek, Ian, Williams, Kenneth M, Day, Richard O“…INTRODUCTION: Hyperuricemia is the greatest risk factor for gout and is caused by an overproduction and/or inefficient renal clearance of urate. …”
Publicado 2012
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1855por Jin, Hye Mi, Kim, Tae-Jong, Choi, Jung-Ho, Kim, Moon-Ju, Cho, Young-Nan, Nam, Kwang-Il, Kee, Seung-Jung, Moon, Jang Bae, Choi, Seok-Yong, Park, Dong-Jin, Lee, Shin-Seok, Park, Yong-Wook“…Immunohistochemistry was performed on formalin-fixed gout tissues with anti–SHIP-1 antibody. A C57BL/6 J male mouse model of gout was used to analyze the expressions of miR-155, SHIP-1, and inflammatory cytokines. …”
Publicado 2014
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1856“…Cox regression produced adjusted hazard ratios (HR) for UA level as continuous and categorical (low, medium, high) predictor for cardiovascular events (CVE) and mortality. Gout was defined as a patient’s self-reported history of gout. …”
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1857por Nyborg, Andrew C., Ward, Chris, Zacco, Anna, Chacko, Benoy, Grinberg, Luba, Geoghegan, James C., Bean, Ryan, Wendeler, Michaela, Bartnik, Frank, O’Connor, Ellen, Gruia, Flaviu, Iyer, Vidyashankara, Feng, Hui, Roy, Varnika, Berge, Mark, Miner, Jeffrey N., Wilson, David M., Zhou, Dongmei, Nicholson, Simone, Wilker, Clynn, Wu, Chi Y., Wilson, Susan, Jermutus, Lutz, Wu, Herren, Owen, David A., Osbourn, Jane, Coats, Steven, Baca, Manuel“…In some people, uric acid levels rise above the solubility limit resulting in crystallization in joints, acute inflammation in response to those crystals causes severe pain; a condition known as gout. Treatment for severe gout includes injection of non-human uricase to reduce serum uric acid levels. …”
Publicado 2016
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1858“…The aim of this study was to verify the protective effects of PEL against gout and explore its underlying mechanism through network pharmacology and animal experiments. …”
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1859por Zhao, Sizheng Steven, Bowes, John, Barton, Anne, Davey Smith, George, Richardson, Tom“…OBJECTIVES: Using Mendelian randomisation (MR), we examined whether childhood body size affects risk of rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), gout and systemic lupus erythematosus (SLE) after accounting for the effect of adult body size. …”
Publicado 2022
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1860por Hill, Catherine L., Appleton, Sarah L., Black, Julie, Hoon, Elizabeth, Rudd, Rima E., Adams, Robert J., Gill, Tiffany“…The prevalence of self-reported arthritis, gout, and osteoporosis was 25.2%, 4.9%, and 5.6%, respectively. …”
Publicado 2015
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