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  1. 1861
    “…Specifically, gout is associated with an accumulation of uric acid within the body resulting from dysregulated purine metabolism, causing recurrent paroxysmal inflammation in the joints. …”
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    Diagnosis and Treatment of Inflammatory Joint Disease
  2. 1862
    “…Gout is the most common arthritic disease in human but was long neglected and therapeutic options are not satisfying. …”
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    Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro
  3. 1863
    “…However, its effects on the inflammatory factors in the process of acute gout inflammation remain unknown. In the present study, we aimed to evaluate the effect of Huzhang Tongfeng granule on the expressions of Cyr61 and related inflammatory factors in both experimental gout models in vivo and in vitro. …”
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    Huzhang Tongfeng Granule Improves Monosodium Urate-Induced Inflammation of Gouty Arthritis Rat Model by Downregulation of Cyr61 and Related Cytokines
  4. 1864
    “…Recent genome-wide association studies have revealed some genetic loci associated with serum uric acid levels and susceptibility to gout/hyperuricemia which contain potential candidates of physiologically important urate transporters. …”
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    Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice
  5. 1865
    “…Gout is a painful and prevalent crystal deposition disease caused by the overproduction of Uric Acid (UA) in the body and the atypical deposition in human synovial joints as Monosodium Urate Monohydrate (MSUM). …”
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    Metal-Assisted and Microwave-Accelerated Decrystallization: An Alternative Approach to Potential Treatment of Crystal Deposition Diseases
  6. 1866
    “…The gosling gout, a newly emerged disease, has widely broken out in China since 2017. …”
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    Application of metagenomic sequencing toward rapid and sensitive diagnosis of goose avastrovirus infection in China
  7. 1867
    “…Gout is one of the most prevalent rheumatic diseases, globally. …”
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    Formulation and Evaluation of a Drug-in-Adhesive Patch for Transdermal Delivery of Colchicine
  8. 1868
    “…The use of uricosuric drugs to treat hyperuricemia in patients with gout is limited by prior urolothiasis or renal dysfunction. …”
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    Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics
  9. 1869
    “…BACKGROUND: Gout is independently associated with increased risk of type 2 diabetes mellitus (T2DM). …”
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    Associations between urate-lowering therapy and the risk of type 2 diabetes mellitus
  10. 1870
    “…BACKGROUND: Gout is a metabolic disease characterized by recurrent episodes of acute arthritis. …”
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    Severe erosive lesion of the glenoid in gouty shoulder arthritis: a case report and review of the literature
  11. 1871
    “…Five studies assessed alcohol consumption in gout, reporting a significant association between the number and type of alcoholic beverages and the occurrence of flares. …”
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    Smoking, alcohol consumption and disease-specific outcomes in rheumatic and musculoskeletal diseases (RMDs): systematic reviews informing the 2021 EULAR recommendations for lifestyle improvements in people with RMDs
  12. 1872
    “…CONCLUSION: Probiotic supplements may improve Hyperuricemia and gout, Inflammatory bowel disease arthritis, JIA, OA, Osteoporosis and Osteopenia, Psoriasis, RA, Spondyloarthritis. …”
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    Safety and efficacy of probiotic supplementation in 8 types of inflammatory arthritis: A systematic review and meta-analysis of 34 randomized controlled trials
  13. 1873
    “…BT stem extract could be used as an anti-hyperuricemia (gout) natural drug or cosmetic material. For further study, practical studies such as optimizing BT extraction and functional experiments for hyperuricemia (gout) and skin wrinkle improvement are considered necessary.…”
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    Strong inhibition of xanthine oxidase and elastase of Baccharis trimera (Less.) DC stem extract and analysis of biologically active constituents
  14. 1874
    “…Patients present with or without pain and thickened tendons. Gout is seen in patients with hyperuricemia. Coexistence of xanthoma and gout is extremely rare. …”
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    An Unusual Case of Xanthoma of Bilateral Achilles Tendon with Gouty Infiltration: A Rare Case Report
  15. 1875
    “…Given the shortcomings of the existing treatments for gout, we investigated whether the MA-MAEC technique can offer an alternative solution to the treatment of gout. …”
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    De-crystallization of Uric Acid Crystals in Synovial Fluid Using Gold Colloids and Microwave Heating
  16. 1876
    “…BACKGROUND: Karapxa decoction (KD) is a Traditional Uighur Medicine used for hepatitis, cholecystitis, gastralgia, oedema, gout and arthralgia. Because of its purported effect in gout, its effects were tested in hyperuricemic mice models induced by yeast extract paste or potassium oxonate, as well as its capacity to scavenge free radicals in vitro. …”
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    Traditional Uighur Medicine Karapxa decoction, inhibits liver xanthine oxidase and reduces serum uric acid concentrations in hyperuricemic mice and scavenges free radicals in vitro
  17. 1877
    “…Data was collected about fertility abnormalities in male patients with systemic lupus erythematosus, rheumatoid arthritis, dermatomyositis, ankylosing spondylitis, Behçet disease and gout. Two independent researchers carried out the search in online databases. …”
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    Male fertility potential alteration in rheumatic diseases: a systematic review
  18. 1878
    “…Gout is the most familiar inflammatory arthritis condition caused by the elevation of uric acid in the bloodstream. …”
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    Investigating the Potential of Transmucosal Delivery of Febuxostat from Oral Lyophilized Tablets Loaded with a Self-Nanoemulsifying Delivery System
  19. 1879
    “…The main goal of our study is the impact evaluation of complex urate-lowering therapy with the synbiotic addition on fecal microbiota and cytokine profile in patients with primary gout. During our study, 130 men (mean age 55.5 ± 9.4 years) with gout (duration 7.7 ± 7.1 years) were examined. …”
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    Impact of the Synbiotics and Urate-Lowering Therapy on Gut Microbiota and Cytokine Profile in Patients with Chronic Gouty Arthritis
  20. 1880
    “…Although gut dysbiosis had been demonstrated to be an important factor affecting hyperuricemia (HUA) and gout, little is known for its potential mechanistic connections. …”
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    Alteration of Gut Microbiome and Correlated Amino Acid Metabolism Contribute to Hyperuricemia and Th17-Driven Inflammation in Uox-KO Mice
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