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  1. 1901
    “…More cohort studies are needed to determine an association between use of allopurinol and the probability of T2DM for individuals with gout and/or hyperuricemia.…”
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    Allopurinol Use and the Risk of Type 2 Diabetes Mellitus: A Meta-Analysis of Cohort Studies
  2. 1902
    “…INTRODUCTION: In phase-3 clinical trials, the interleukin (IL-1) blocker, rilonacept (IL-1 Trap), demonstrated efficacy for gout flare prevention during initiation of urate-lowering therapy. …”
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    Rilonacept in the treatment of acute gouty arthritis: a randomized, controlled clinical trial using indomethacin as the active comparator
  3. 1903
    “…BACKGROUND: Hyperuricemia and gout have become public health concerns; many important guidelines have recommended xanthine oxidase inhibitors (XOIs) as the first-line urate-lowering therapies (ULTs) to treat chronic gout with hyperuricemia. …”
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    Cardiovascular events in hyperuricemia population and a cardiovascular benefit-risk assessment of urate-lowering therapies: a systematic review and meta-analysis
  4. 1904
    “…Ultrasound to identify elementary lesions was assessed in 38 studies in OA, gout and CPPD. Its performance in OA was very variable, with better results in CPPD and gout. …”
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    Differential Diagnosis of Inflammatory Arthropathies by Musculoskeletal Ultrasonography: A Systematic Literature Review
  5. 1905
    “…BACKGROUND: Along with uric acid, which is the primary driving factor of gout, downstream inflammatory mediators have been shown to be involved in the pathogenesis of gouty arthritis flares. …”
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    Plasma adsorption in refractory chronic gouty arthritis flare: A case report
  6. 1906
    Libro
    Fisiología del gusto con una lectura de Roland Barthes
  7. 1907
    “…Elevated serum urate concentration is the primary cause of gout. Understanding the processes that affect serum urate concentration is important for understanding the etiology of gout and thereby understanding treatment. …”
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    Urate Handling in the Human Body
  8. 1908
    “…He had medical histories of type 2 diabetes, hyperlipidemia, hyperuricemia, and gout attack. He received favipiravir for compassionate use for 14 days. …”
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    Acute Gouty Arthritis During Favipiravir Treatment for Coronavirus Disease 2019
  9. 1909
    “…Recent epidemiological evidence has shown an increasing trend in the prevalence of hyperuricemia and gout in the Western world: a number of population-based studies estimate a prevalence of up to 21% for hyperuricemia and 1%–4% for gout. …”
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    An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia
  10. 1910
    “…BACKGROUND: Gout, a common medical condition that causes pain, can be treated by painkillers and anti-inflammatories. …”
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    Do etoricoxib and indometacin have similar effects and safety for gouty arthritis? A meta-analysis of randomized controlled trials
  11. 1911
    por Alqarni, Norah A., Hassan, Abdul H.
    Publicado 2018
    “…Predictors of ULT misuse included the percentage of patients having gout (1-10%: OR=5.40, p=0.047) or receiving ULT (>10-20%: OR=20.02, p=0.001)among patients seen in clinic, attendance of rheumatology conferences (OR=2.55, p=0.017), and having a close relative with hyperuricemia or gout (OR=2.45, p=0.026). …”
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    Knowledge and practice in the management of asymptomatic hyperuricemia among primary health care physicians in Jeddah, Western Region of Saudi Arabia
  12. 1912
    “…OBJECTIVE: We have conducted this study to evaluate clinical and laboratory findings and to gather and evaluate information that would be useful in clinical practice, such as demographics, joint involvement patterns, laboratory anomalies, treatments applied, and responses obtained in patients diagnosed with gout. METHODS: In our study, the demographic, clinical, and laboratory characteristics of 94 patients diagnosed with gout were evaluated. …”
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    Demographic, clinical, and laboratory features of Turkish patients with gouty arthritis: A prospective cohort study
  13. 1913
    “…Elevated uric acid (UA) is a key risk factor for many disorders, including metabolic syndrome, gout and kidney stones. Despite frequent occurrence of these disorders, the genetic pathways influencing UA metabolism and the association with disease remain poorly understood. …”
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    A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster
  14. 1914
    “…Gout is an inflammatory arthritis due to the joint deposition of monosodium urate (MSU) crystals. …”
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    Design and Biological Evaluation of Colchicine-CD44-Targeted Peptide Conjugate in an In Vitro Model of Crystal Induced Inflammation
  15. 1915
    “…METHODS: Japanese health insurance claims and medical check‐up data from October 2015 to March 2017 were analyzed to assess factors associated with target sUA achievement in gout and asymptomatic hyperuricemia and gouty arthritis in gout. …”
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    Factors associated with achieving target serum uric acid level and occurrence of gouty arthritis: A retrospective observational study of Japanese health insurance claims data
  16. 1916
    por Botson, John K., Peterson, Jeff
    Publicado 2022
    “…Pegloticase is used for treatment of refractory gout, which has failed maximal medical management, but only 42% of patients respond completely to treatment because of the presumed development of antidrug antibodies, which rapidly clear the pegloticase molecule. …”
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    Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series
  17. 1917
    “…AIM: Gout is the most common form of inflammatory arthritis in men. …”
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    Persistence with urate‐lowering therapy in Australia: A longitudinal analysis of allopurinol prescriptions
  18. 1918
    “…Hyperuricemia has long been established as the major etiologic factor in gout. In recent years, a large body of evidence has accumulated that suggests that hyperuricemia may play a role in the development and pathogenesis of a number of metabolic, hemodynamic, and systemic pathologic diseases, including metabolic syndrome, hypertension, stroke, and atherosclerosis. …”
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    Review of Hyperuricemia as New Marker for Metabolic Syndrome
  19. 1919
    “…Visceral urate deposition (visceral gout) is a common finding during post-mortem examination of poultry. …”
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    Visceral urate deposition in a little bittern (Ixobrychus minutus)
  20. 1920
    “…Gout is the most common form of inflammatory arthritis and is a multifactorial disease typically characterized by hyperuricemia and monosodium urate crystal deposition predominantly in, but not limited to, the joints and the urinary tract. …”
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    Online Artículo Texto
    Physiology of Hyperuricemia and Urate-Lowering Treatments
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