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  1. 3741
    “…Secondary outcomes include incidence of hospital outbreaks, with and without sequencing data; actual and desirable changes to IPC actions; periods of healthcare worker (HCW) absence. Health economic analysis will be conducted to determine cost benefit of the intervention. …”
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    Protocol for the COG-UK hospital-onset COVID-19 infection (HOCI) multicentre interventional clinical study: evaluating the efficacy of rapid genome sequencing of SARS-CoV-2 in limiting the spread of COVID-19 in UK NHS hospitals
  2. 3742
    “…Consideration should be put toward development of a disease-specific preference-based measure for health economic evaluation. LEVEL OF EVIDENCE: 4.…”
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    Construct Validity of the EuroQoL–5 Dimension and the Health Utilities Index in Head and Neck Cancer
  3. 3743
    “…Data were adjusted for patient‐specific variables (demographic, disease‐specific) and health economic data (gross domestic product, health expenditure per capita). …”
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    Variations in end‐of‐life care practices in older critically ill patients with COVID‐19 in Europe
  4. 3744
    “…Streamlining the management of venous ulcers has broad health economic benefits. If it is found that TIRS is superior or non-inferior to AA, then a less expensive, less invasive injection can be offered as an alternative to AA in an attempt to encourage the healing of venous ulcers. …”
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    Axial ablation versus terminal interruption of the reflux source (AAVTIRS): a randomised controlled trial
  5. 3745
    “…Embedded within the trial will be a health economic evaluation to understand resource utilisation and implications of the intervention and a qualitative study of the experiences and insights of trial participants and clinicians. …”
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    The Acute VertEbRal AugmentaTion (AVERT) study: protocol for a randomised controlled, feasibility trial of spinal medial branch nerve block in hospitalised older patients with vertebral fragility fractures
  6. 3746
    “…Secondary outcomes include effects of the intervention on activities of daily living, mood and anxiety, vestibular function recovery, mobility measures, health economic effects, and the reliability of the Swedish VSS-SF translation. …”
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    Internet-based vestibular rehabilitation versus standard care after acute onset vertigo: a study protocol for a randomized controlled trial
  7. 3747
    “…We will invite service users to complete health economic measures at baseline, 3, 6, 9 and 12-month follow-up. …”
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    Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists
  8. 3748
    “…Secondary outcomes are depression at discharge (T1) and 6 months follow-up (T2) as well as anxiety, satisfaction with participation in social roles and activities, pain impairment, fatigue, sleep, health-related quality of life, self-efficacy, physical functioning, alcohol, personality and health economic-specific general quality of life and socioeconomic cost and benefits at T1-3. …”
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    Effectiveness and cost-effectiveness of a web-based routine assessment with integrated recommendations for action for depression and anxiety (RehaCAT+): protocol for a cluster randomised controlled trial for patients with elevated depressive symptoms in rehabilitation facilities
  9. 3749
    “…This study evaluates the efficacy and cost-effectiveness of an integrated care model combining Buprenorphine treatment of OUD with OPAT for SIRI (B-OPAT) compared with treatment as usual on key OUD, infectious disease, and health economic outcomes. B-OPAT expands and incorporates key elements of established clinical models, including inpatient initiation of buprenorphine for OUD, inpatient infectious disease consultation for SIRI, office-based treatment of OUD, and OPAT, and includes more frequent clinical outpatient visits than standard OPAT. …”
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    Design and protocol of the Buprenorphine plus Outpatient Parenteral Antimicrobial Therapy (B-OPAT) study: a randomized clinical trial of integrated outpatient treatment of opioid use disorder and severe, injection-related infections
  10. 3750
    “…(1) Background: Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) continues to cause profound health, economic, and social problems worldwide. The management and disinfection of materials used daily in health centers and common working environments have prompted concerns about the control of coronavirus disease 2019 (COVID-19) infection risk. …”
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    Ozone Eliminates SARS-CoV-2 from Difficult-to-Clean Office Supplies and Clinical Equipment
  11. 3751
    “…We used a modified version of the Consolidated Health Economic Evaluation Reporting Standards checklist to appraise the studies. …”
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    Direct medical costs of young-onset colorectal cancer: a worldwide systematic review
  12. 3752
    “…BACKGROUND: The current COVID-19 pandemic affects the entire world population and has serious health, economic and social consequences. Assessing the prevalence of COVID-19 through population-based serological surveys is essential to monitor the progression of the epidemic, especially in African countries where the extent of SARS-CoV-2 spread remains unclear. …”
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    High seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based study
  13. 3753
    “…In the six-month period following discharge, a health-economic evaluation will be carried out based on routine health insurance data (t3). …”
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    Reduction of care-relevant risks to older patients during and after acute hospital care (ReduRisk) – study protocol of a cluster randomized efficacy trial in a stepped wedge design
  14. 3754
    “…We employed an established health economic modeling and analytical framework to quantify cost-effectiveness and value of information. …”
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    Artificial Intelligence for Caries Detection: Value of Data and Information
  15. 3755
    “…BACKGROUND: The Coronavirus disease 2019 (COVID-19) has presented a major challenge to the health, economic, and social sectors of the entire world. …”
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    The impact of the COVID-19 pandemic on the mental health and academic performance of medical postgraduates
  16. 3756
    “…We aimed to analyse the value of ICU treatment of COVID‐19 from a patient‐centred health economic perspective. We prospectively included 49 patients with severe COVID‐19 and calculated direct medical treatment costs. …”
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    Intensive care unit resources and patient‐centred outcomes in severe COVID‐19: a prospective single‐centre economic evaluation
  17. 3757
    “…Additional secondary outcomes of interest include safety, the feasibility of province-wide implementation of the strategy into routine care, and health economic assessment from a patient and health systems perspective. …”
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    Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment (SMARTT): a study protocol for a phase IV pragmatic randomized controlled patient management strategy trial
  18. 3758
    “…While the tool was evaluated by potential users, more research is needed to further improve the tool, especially health-economic studies, to ensure efficient and cost-effective implementation of SDR-PEP.…”
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    Implementation approaches for leprosy prevention with single-dose rifampicin: A support tool for decision making
  19. 3759
    “…The study will consist of three parts: 1) an effectiveness evaluation, 2) a health-economic evaluation, and 3) a process implementation evaluation. …”
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    (Cost)-effectiveness and implementation of integrated community-based care for patients with severe mental illness: a study protocol
  20. 3760
    “…This is a background study to a broader health economic evaluation, seeking to document the costs of integrated case management of NTDs versus standard care in Liberia. …”
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    Financing care for Severe Stigmatizing Skin Diseases (SSSDs) in Liberia: challenges and opportunities
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