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Hepatitis B
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2
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1
Carcinogénesis química
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1
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1
Enfermedades transmisibles
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Hepatitis
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1
Hepatitis B.
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2081Hepatitis B virus genotypes circulating in Brazil: molecular characterization of genotype F isolatespor Mello, Francisco CA, Souto, Francisco JD, Nabuco, Leticia C, Villela-Nogueira, Cristiane A, Coelho, Henrique Sergio M, Franz, Helena Cristina F, Saraiva, Joao Carlos P, Virgolino, Helaine A, Motta-Castro, Ana Rita C, Melo, Mabel MM, Martins, Regina MB, Gomes, Selma A“…BACKGROUND: Hepatitis B virus (HBV) isolates have been classified in eight genotypes, A to H, which exhibit distinct geographical distributions. …”
Publicado 2007
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2082“…However, this model is not available for hepatitis B virus (HBV) infection. As the enhanced recruitment of virus-specific CTLs into the liver has been an important novel concept in the pathogenesis of hepatitis B, we develop a specific mathematical model analyzing the relationship between HBV and the CTL-mediated immune response, and the indicator of the liver cell damage, alanine aminotransferase (ALT). …”
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2083Publicado 1992“…Expression of hepatitis B surface antigen (HBsAg), the major envelope protein of the virus, in the absence of other viral proteins leads to its secretion as oligomers in the form of disk-like or tubular lipoprotein particles. …”
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2084por Makidon, Paul E., Bielinska, Anna U., Nigavekar, Shraddha S., Janczak, Katarzyna W., Knowlton, Jessica, Scott, Alison J., Mank, Nicholas, Cao, Zhengyi, Rathinavelu, Sivaprakash, Beer, Michael R., Wilkinson, J. Erby, Blanco, Luz P., Landers, Jeffrey J., Baker, James R.“…BACKGROUND: Hepatitis B virus infection remains an important global health concern despite the availability of safe and effective prophylactic vaccines. …”
Publicado 2008
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2085por Cheong, Jae Youn, Cho, Sung Won, Lee, Jung A, Lee, Kwang Jae, Wang, Hee Jung, Lee, Jong Eun, Kim, Jin Hong“…The reasons for the viral persistence of hepatitis B virus (HBV) infection are unknown, but are probably related to host immune factors. …”
Publicado 2008
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2086por Zhang, H W, Yin, J H, Li, Y T, Li, C Z, Ren, H, Gu, C Y, Wu, H Y, Liang, X S, Zhang, P, Zhao, J F, Tan, X J, Lu, W, Schaefer, S, Cao, G W“…BACKGROUND AND AIMS: The major risk factors for acute hepatitis B (AHB) in China and the viral factors determining the progression from acute to chronic hepatitis B remain largely unknown. …”
Publicado 2008
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2087por Li, Lie, Oropeza, Claudia E., Sainz, Bruno, Uprichard, Susan L., Gonzalez, Frank J., McLachlan, Alan“…The host cellular factors that promote persistent viral infections in vivo are, in general, poorly understood. Utilizing the hepatitis B virus (HBV) transgenic mouse model of chronic infection, we demonstrate that the nuclear receptor, hepatocyte nuclear factor 4α (HNF4α, NR2A1), is essential for viral biosynthesis in the liver. …”
Publicado 2009
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2088
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2089“…BACKGROUND/AIMS: Chronic hepatitis B is a serious global health problem. Liver biopsy is currently recommended as the gold standard for the evaluation of the degree of fibrosis in patients with chronic hepatitis B. …”
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2090por Liaw, Yun-Fan, Leung, Nancy, Kao, Jia-Horng, Piratvisuth, Teerha, Gane, Edward, Han, Kwang-Hyub, Guan, Richard, Lau, George K. K., Locarnini, Stephen“…Large amounts of new data on the natural history and treatment of chronic hepatitis B virus (HBV) infection have become available since 2005. …”
Publicado 2008
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2091por Yeh, Chau-Ting, Kuo, Chia-Jung, Lai, Ming-Wei, Chen, Tse-Ching, Lin, Chun-Yen, Yeh, Ta-Sen, Lee, Wei-Chen“…The aim of this study was to investigate the significance of CD133 expression in HCC in an area endemic for hepatitis B virus (HBV) infection to gain insights on this issue. …”
Publicado 2009
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2092por Deng, Lei, Li, Guoqiang, Xi, Lisen, Yin, Aihong, Gao, Yun, You, Wei, Wang, Xuehao, Sun, Beicheng“…BACKGROUND: Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. …”
Publicado 2009
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2093por Ma, Yan, Yu, Jun, Chan, Henry L. Y., Chen, Yang-chao, Wang, Hua, Chen, Ying, Chan, Chu-yan, Go, Minnie Y. Y., Tsai, Sau-na, Ngai, Sai-ming, To, Ka-fai, Tong, Joanna H. M., He, Qing-Yu, Sung, Joseph J. Y., Kung, Hsiang-fu, Cheng, Christopher H. K., He, Ming-liang“…Hepatitis B virus (HBV) infection is a global public health problem that plays a crucial role in the pathogenesis of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. …”
Publicado 2009
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2094por Bae, Si Hyun, Yoon, Seung Kew, Jang, Jeong Won, Kim, Chang Wook, Nam, Soon Woo, Choi, Jong Young, Kim, Boo Sung, Park, Young Min, Suzuki, Seiji, Sugauchi, Fuminaka, Mizokami, Masashi“…Hepatitis B virus (HBV) is one of the major causative agents of chronic liver diseases in Korea. …”
Publicado 2005
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2095por Sivakumar, S. M., Sukumaran, N., Murugesan, R., Shanmugarajan, T. S., Anbu, J., Sivakumar, L., Anilbabu, B., Srinivasarao, G., Ravichandran, V.“…The present study was aimed to replace the alum type adjuvant for hepatitis B vaccine. The hepatitis B vaccine was encapsulated in poly (DL-lactide-co-glycolide) microspheres by solvent evaporation technique. …”
Publicado 2008
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2096por Scott-Algara, Daniel, Mancini-Bourgine, Maryline, Fontaine, Hélène, Pol, Stanislas, Michel, Marie-Louise“…We previously reported the induction or reactivation of T cell responses in chronic hepatitis B patients vaccinated with a DNA encoding hepatitis B envelope proteins during a phase I clinical trial. …”
Publicado 2010
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2097por Schmitz, André, Schwarz, Alexandra, Foss, Michael, Zhou, Lixin, Rabe, Birgit, Hoellenriegel, Julia, Stoeber, Miriam, Panté, Nelly, Kann, Michael“…Virtually all DNA viruses including hepatitis B viruses (HBV) replicate their genome inside the nucleus. …”
Publicado 2010
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2098Chronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directionspor Ahn, Sang Hoon, Chan, Henry L. Y., Chen, Pei-Jer, Cheng, Jun, Goenka, Mahesh K., Hou, Jinlin, Lim, Seng Gee, Omata, Masao, Piratvisuth, Teerha, Xie, Qing, Yim, Hyung Joon, Yuen, Man-Fung“…Recent guidelines of the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association for the Study of the Liver 2008 update of the “Asian-Pacific consensus statement on the management of chronic hepatitis B” offer comprehensive recommendations for the general management of chronic hepatitis B (CHB). …”
Publicado 2010
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2099
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2100“…Peginterferon offers the advantage of higher sustained response rates in both hepatitis B early antigen (HBeAg)-positive and HBeAg-negative patients, at the price of considerable side effects and high costs. …”
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