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15081“…Patients with chronic hepatitis B (CHB, n=193) and non-CHB (n=111) were stratified by four liver stiffness measurement (LSM) thresholds. …”
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15082Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpointpor Schmidt, Nathalie M., Wing, Peter A. C., Diniz, Mariana O., Pallett, Laura J., Swadling, Leo, Harris, James M., Burton, Alice R., Jeffery-Smith, Anna, Zakeri, Nekisa, Amin, Oliver E., Kucykowicz, Stephanie, Heemskerk, Mirjam H., Davidson, Brian, Meyer, Tim, Grove, Joe, Stauss, Hans J., Pineda-Torra, Ines, Jolly, Clare, Jury, Elizabeth C., McKeating, Jane A., Maini, Mala K.“…Here, we show that ACAT inhibition has antiviral activity against hepatitis B (HBV), as well as boosting protective anti-HBV and anti-hepatocellular carcinoma (HCC) T cells. …”
Publicado 2021
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15083por Paik, James M., Golabi, Pegah, Younossi, Youssef, Saleh, Nazaneen, Nhyira, Annan, Younossi, Zobair M.“…Our aim was to assess the CLD burden within the United States between 2007 and 2017 based on the most common causes of CLD: hepatitis B virus, hepatitis C virus (HCV), alcoholic liver disease (ALD), and nonalcoholic fatty liver disease (NAFLD). …”
Publicado 2021
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15084por Bogers, S.J., Hulstein, S.H., Schim van der Loeff, M.F., de Bree, G.J., Reiss, P., van Bergen, J.E.A.M, Geerlings, S.E.“…METHODS: Seven ICs were selected: tuberculosis (TB), malignant lymphoma, hepatitis B, hepatitis C, cervical/vulvar carcinoma/intraepithelial neoplasia grade 2+ (CC/CIN2+, VC/VIN2+), and peripheral neuropathy (PN). …”
Publicado 2021
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15085“…Experimental R(1) measurements in the 61 nucleotide human hepatitis B virus encapsidation signal ε RNA labeled with [U-(13)C/(15)N]-ATP or [2-(13)C]-ATP corroborate these simulations. …”
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15086por Budroni, Sonia, Buricchi, Francesca, Cavallone, Andrea, Bourguignon, Patricia, Caubet, Magalie, Dewar, Vincent, D’Oro, Ugo, Finco, Oretta, Garçon, Nathalie, El Idrissi, Mohamed, Janssens, Michel, Leroux-Roels, Geert, Marchant, Arnaud, Schwarz, Tino, Van Damme, Pierre, Volpini, Gianfranco, van der Most, Robbert, Didierlaurent, Arnaud M., Burny, Wivine“…We compared antibody avidity maturation, antibody/memory B cell/CD4(+) T cell response durability, and recall responses to non-adjuvanted fractional-dose antigen administered 1-year post-immunization (Day [D]360), between hepatitis B vaccines containing Adjuvant System (AS)01(B), AS01(E), AS03, AS04, or Alum (NCT00805389). …”
Publicado 2021
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15087por Surana, Pallavi, Hercun, Julian, Takyar, Varun, Kleiner, David E, Heller, Theo, Koh, Christopher“…METHODS: Clinical, biochemical and histologic laboratory data from treatment naive chronic viral hepatitis B (HBV), C (HCV), and D (HDV) patients at the NIH Clinical Center from 1985-2019 were collected and subjects were randomly divided into training and validation cohorts. …”
Publicado 2021
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15088por Grosser, Gary, Müller, Simon Franz, Kirstgen, Michael, Döring, Barbara, Geyer, Joachim“…Na(+)/taurocholate cotransporting polypeptide NTCP is a hepatic bile acid transporter and the cellular entry receptor for the hepatitis B and D viruses. Its intestinal counterpart, apical sodium-dependent bile acid transporter ASBT, is responsible for the reabsorption of bile acids from the intestinal lumen. …”
Publicado 2021
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15089“…To understand the characteristic of changes of serum metabolites between healthy people and patients with hepatitis B virus (HBV) infection at different stages of disease, and to provide reference metabolomics information for clinical diagnosis of liver disease patients. 255 patients with different stages of HBV infection were selected. 3 mL blood was collected from each patient in the morning to detect differences in serum lysophosphatidylcholine, acetyl-l-carnitine, oleic acid amide, and glycocholic acid concentrations by UFLC-IT-TOF/MS. …”
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15090por Asemota, Joseph, Oladunjoye, Olubunmi, Babalola, Atinuke, Nwosu, Ugonna, Liu, Po-Hong S, Oladunjoye, Adeolu O, Castro-Webb, Nelsy, Miksad, Rebecca A“…Results: Compared to non-Hispanic White patients (n=89), Hispanic HCC patients (n=59) were more likely to have chronic hepatitis C infection (69.5% vs. 38.2%, p < 0.01), alcoholic liver disease (37.3% vs. 21.4%, p = 0.04) and were less likely to have chronic hepatitis B infection (6.8% vs. 24.7%, p = 0.01), and private insurance (37.3% vs. 57.3%, p = 0.02). …”
Publicado 2021
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15091por Yang, Geunhyeok, Hwang, Shin, Ahn, Chul-Soo, Kim, Ki-Hun, Moon, Deok-Bog, Ha, Tae-Yong, Song, Gi-Won, Jung, Dong-Hwan, Park, Gil-Chun, Hong, Seung-Mo“…RESULTS: Mean age of the patients was 42.6±11.4 years and there were 30 (75.0%) females. Hepatitis B and C virus infection was present in 8 patients (20.0%) and 1 patient (2.5%), respectively. …”
Publicado 2021
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15092por Wigg, Alan J, Narayana, Sumudu K, Hartel, Gunter, Medlin, Linda, Pratt, Greg, Powell, Elizabeth E., Clark, Paul, Davies, Jane, Campbell, Kirsty, Toombs, Maree, Larkin, Michael, Valery, Patricia C“…The distribution of cofactors was also significantly different for Indigenous Australians including higher prevalence of alcohol misuse, hepatitis B, and diabetes and more frequent presence of multiple HCC cofactors (all p < 0.001). …”
Publicado 2021
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15093por Huang, Jingjun, Huang, Wensou, Guo, Yongjian, Cai, Mingyue, Zhou, Jingwen, Lin, Liteng, Zhu, Kangshun“…RESULTS: A total of 249 patients with a single, hepatitis-B virus (HBV)-related HCC ≤ 5.0 cm who underwent RFA (HCC ≤ 3.0 cm) or TACE-RFA (HCC of 3.1-5.0 cm) were included. …”
Publicado 2021
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15094“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis demonstrated that ingredients affect networks mainly in nuclear receptor activity and G protein-coupled amine receptor activity; besides, fluid shear stress and atherosclerosis, human cytomegalovirus infection, and hepatitis B signaling pathways might be the principal therapy ways. …”
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15095“…KEGG analysis demonstrated that the predicted genes were enriched in the p53 signaling pathway and hepatitis B, etc. Through constructing a PPI network, the genes with the highest connectivity were identified as hub genes. …”
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15096por Farfour, Eric, Dimi, Svetlane, Chassany, Olivier, Fouéré, Sébastien, Valin, Nadia, Timsit, Julie, Ghosn, Jade, Duvivier, Claudine, Duracinsky, Martin, Zucman, David“…Etiologic diagnosis of STIs including hepatitis B, C, syphilis, was performed using a serological test, including a non-treponemal titer with a confirmatory treponemal assay for syphilis. …”
Publicado 2021
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15097por Esagian, Stepan M., Kakos, Christos D., Giorgakis, Emmanouil, Burdine, Lyle, Barreto, J. Camilo, Mavros, Michail N.“…Meta-regression analyses were performed to explore the effect of hepatitis B viral status, microvascular invasion, type of resection (anatomic vs. parenchymal-sparing), and tumor size on the outcomes. …”
Publicado 2021
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15098por Islam, Mohammad Manirul, Hossain, Fahima, Sakib, Najmuj, Zeba, Zebunnesa, Bhuiyan, A K M Israfil, Mamun, Mohammed A, Kaggwa, Mark Mohan, Yoshimura, Ken, Afrin, Sadia, Selim, Sheikh, Hossain, Moazzem“…The hemoglobinopathies were significantly associated with the individuals who had a family history of thalassemia and were not vaccinated against hepatitis B in the total sample. Although not statistically suggestive, the most considerable portion (87.3%) of the carriers was unmarried in the present findings. …”
Publicado 2021
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15099por Wang, Aili, Ji, Zhibin, Xuan, Rong, Zhao, Xiaodong, Hou, Lei, Li, Qing, Chu, Yunpeng, Chao, Tianle, Wang, Jianmin“…MiRNA target genes in significant pathways were significantly enriched in Hepatitis B (FDR = 9.03E-10) and Pathways in cancer (FDR = 4.2E-10). …”
Publicado 2021
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15100por Chen, Andre Tsin Chih, Payão, Fabio, Chagas, Aline Lopes, De Souza Melo Alencar, Regiane Saraiva, Tani, Claudia Megumi, da Conceição Vasconcelos, Karina Gondim Moutinho, de Souza Rocha, Manoel, de Andrade Carvalho, Heloisa, Hoff, Paulo Marcelo Gehm, Carrilho, Flair José“…Underlying liver disease was hepatitis C, hepatitis B and alcohol-related in, respectively, 50%, 23% and 19% of patients. …”
Publicado 2021
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